Clinical trials: Post Acute COVID 19 Syndrome
Persistent COVID-19, Quality of Life
Vascular Structure, Vascular Function and Vascular Aging in Adults Diagnosed With Persistent COVID
The ICOPER study aims to analyze the structure, vascular function, vascular aging and determining factors in 300 adults diagnosed with Persistent Covid in the field of Primary Health Care.
- Conditions
- Persistent COVID-19, Quality of Life, Lifestyles, Arterial Stiffness
- Trial name
- ICOPER (NCT05819840)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis
We are studying the effect of a mind-body treatment for people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with or without Long COVID (LC).
- Trial name
- MILES (NCT06933173)
- Testing
- Dynamic neural retraining system
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Alberta
Post-COVID-19 Syndrome, Fatigue Post Viral
Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19 Syndrome
Evaluation of the short- and medium-term effect of a yoga intervention in addition to routine care compared to health education in addition to routine care on fatigue in patients with post covid syndrome.
- Trial name
- YoFaPoCo (NCT05890599)
- Testing
- Yoga Therapy, Health Education
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
SARS-CoV-2 Infection, COVID-19
An Open-label, Clinical Feasibility Study of the Efficacy of Remdesivir for Long-COVID.
Following an infection with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV2), one in ten people will experience persisting symptoms, or develop symptoms which can last for months and even years.
- Trial name
- ERASE-LC (NCT05911906)
- Testing
- Remdesivir
- Where
- 4 sites in United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Derby
Diaphragm Injury, Pathology
Effects of Mechanical Ventilation on the Diaphragm in COVID-19 Intensive Care Patients. A Post-mortem Pathology Study
The diaphragm is the fundamental muscle of the respiratory system. The diaphragmatic dysfunction is present in 60% of critical patients at hospital admission and up to 80% after prolonged mechanical ventilation and difficult…
- Conditions
- Diaphragm Injury, Pathology, COVID-19 Acute Respiratory Distress Syndrome, Ventilation Therapy; Complications
- Trial name
- NCT05191433
- Where
- 2 sites in Italy
- Volunteers
- 41 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Long Covid19, Fatigue Syndrome, Chronic
Effects of Cacao Flavonoids in Long COVID-19 Patients (FLALOC)
The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo to evaluate the effect of daily consumption of a cacao supplement on inflammation, endothelial damage, handgrip strength…
- Trial name
- FLALOC (NCT06064838)
- Testing
- Flavonoids
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Guillermo Ceballos Reyes
Post-Acute COVID-19 Syndrome
Role of OMT in the Management of the Persistent Post-COVID-19 Symptoms
The goal of this observational study is to determine the feasibility of conducting a large-scale study on the effect of using osteopathic manipulative treatment (OMT) to treat patients with post-COVID-19 symptoms.
- Trial name
- ROMPS (NCT06016543)
- Testing
- osteopathic manipulative treatment (OMT)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- A.T. Still University of Health Sciences
Long COVID, Post-COVID-19 Condition
A Study of Human Umbilical Cord Blood (REGENECYTE) Infusion in Patients With Post-COVID Condition
REGENECYTE (HPC, Cord Blood) for treatment in patients with post-COVID.
- Conditions
- Long COVID, Post-COVID-19 Condition, Post-COVID Syndrome, Post-COVID Condition
- Trial name
- NCT07184385
- Testing
- REGENECYTE
- Volunteers
- 60 people
- Sponsor
- StemCyte, Inc.
Post-Acute COVID-19 Syndrome
Enhanced External Counterpulsation to Treat Long COVID-19 Fatigue
The goal of this double blind, outcome-assessor blind, randomized controlled trial, is to compare the effectiveness of external encounter counterpulsation (EECP) versus sham procedure in participants with long COVID-19 fatigue.
- Trial name
- EXPECT (NCT05668039)
- Testing
- Enhanced external counterpulsation
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Sheba Medical Center
COVID-19, Long COVID
BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients
This is a randomized, double-blinded, placebo-controlled, two-arm study to evaluate the safety and efficacy of BIO 300 Oral Suspension (BIO 300) as a therapy to improve lung function in patients that were hospitalized for severe…
- Conditions
- COVID-19, Long COVID, Pulmonary Fibrosis, Post-acute Respiratory Complications of COVID-19
- Trial name
- NCT04482595
- Testing
- BIO 300 Oral Suspension
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Humanetics Corporation
Covid19, Long COVID-19
Pilot Study Into LDN and NAD+ for Treatment of Patients With Post-COVID-19 Syndrome
Pilot study into low dose naltrexone (LDN) and NAD+ for treatment of patients with post-COVID-19 syndrome.
- Conditions
- Covid19, Long COVID-19, Post-COVID-19 Syndrome
- Trial name
- NCT04604704
- Testing
- Naltrexone, NAD+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- AgelessRx
Gastrointestinal Post Acute COVID-19 Syndrome
The Clinical Significance of Gut Permeability in Gastrointestinal Post Acute COVID-19 Syndrome
Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) and the associated coronavirus disease 2019 (COVID-19) have been spreading all around the world for past 3 years.
- Trial name
- NCT05612087
- Testing
- Confocal laser endomicroscopy
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Long COVID-19, Acute COVID-19
Long COVID-19 Cutaneous Signatures: An ARPA Funded Research Project
This is a prospective, longitudinal study involving 300 participants for a single visit to compare Long COVID-19 neurocutaneous biosignatures with those of other disorders affecting the sensory and autonomic nervous system.
- Conditions
- Long COVID-19, Acute COVID-19, Postural Orthostatic Tachycardia Syndrome (POTS), Diabetic Neuropathy
- Trial name
- LCCS (NCT07005947)
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- CND Life Sciences
Neurocognitive Disorders, Cognitive Dysfunction
A Pilot Randomized Controlled Trial: CoINTEGRATE
The purpose of this study is to examine the feasibility of comprehensive multimodal individually tailored Cognitive Behavioral Therapy (CBT), Cognitive Rehabilitation Therapy (CRT), and modifiable lifestyle sessions.
- Conditions
- Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis
- Trial name
- CoINTEGRATE (NCT05732285)
- Testing
- CRT, CBT, Modifiable lifestyle factors
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Covid19, LONG-COVID
Early and Late Complications of COVID-19
Coronavirus disease 2019 (COVID-19) is a serious respiratory disease that results from infection with a newly discovered coronavirus (SARS-COV-2). Unfortunately, COVID-19 is not only a short-term infection.
- Trial name
- NCT05018052
- Where
- Poland
- Volunteers
- 1,900 people
- Sponsor
- Michal Chudzik
COVID-19, COVID Long-Haul
Comprehensive Imaging Exam of Convalesced COVID-19 Patients
COVID-19 is a systemic inflammatory disease involving many organs including the lungs, vascular system liver and myocardium that lead to severe pathologies.
- Trial name
- NCT05920616
- Testing
- Magnetic Resonance Imaging, Ultra-High Resolution Computed Tomography (CT) Scan
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Johns Hopkins University
Long COVID, Distress Tolerance
Long COVID-19 Intervention Using Digital Health & Technology
The current study seeks to pilot test the iENDURE (Enhancing Distress tolerance to Uplift motivation in Recovery) intervention among 10 participants with Long COVID (Coronavirus Disease) symptoms.
- Trial name
- LIGHT (NCT05616806)
- Testing
- iENDURE
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Long Covid19, Post COVID-19 Condition
All Eyes on PCS - Analysis of the Retinal Microvasculature in Patients With Post-COVID-19 Syndrome
The goal of this observational, prospective study is to in depth analyze the retinal microvasculature in patients with Post-COVID-19 Syndrome (PCS).
- Conditions
- Long Covid19, Post COVID-19 Condition, Endothelial Dysfunction
- Trial name
- NCT05635552
- Testing
- Dynamic retinal vessel analysis (DVA), Optical coherence tomography (OCT), Biochemistry and immune phenotyping
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Long COVID, Fatigue
Long COVID-19 Fatigue and Obstructive Sleep Apnea
Identify the relationship of obstructive sleep apnea (OSA) prevalence with post-COVID-19 fatigue that remains at least six months after acute disease
- Conditions
- Long COVID, Fatigue, Obstructive Sleep Apnea of Adult
- Trial name
- PostCoV2OSA (NCT05290350)
- Testing
- OSA
- Where
- 12 sites in Portugal
- Volunteers
- 300 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Long COVID
tDCS in the Management of Post-COVID Disorders
Different physical and mental morbidities such as pain, fatigue, depressed mood and cognitive impairment can be triggered by coronavirus infection.
- Trial name
- tDCS (NCT06074848)
- Testing
- Transcranial Direct Current Stimulation (tDCS), Motor Training, Cognitive Training
- Where
- 2 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- Universidade Federal de Pernambuco