Clinical trials: Post Acute COVID 19 Syndrome
Post-Acute COVID-19 Syndrome, Lung Disease With Polymyositis
Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID-19
The goal of this clinical study is to evaluate the efficacy and safety of Longidaza®, lyophilisate for preparation of solution for injection, at a dose of 3000 IU compared to placebo in the treatment of adult patients with…
- Conditions
- Post-Acute COVID-19 Syndrome, Lung Disease With Polymyositis, Fibrosis, Lung Diseases, Interstitial
- Trial name
- NCT06383819
- Testing
- Longidaza®
- Where
- 30 sites in Russia
- Volunteers
- 392 people
- Sponsor
- NPO Petrovax
Long COVID-19, Acute COVID-19
Long COVID-19 Cutaneous Signatures: An ARPA Funded Research Project
This is a prospective, longitudinal study involving 300 participants for a single visit to compare Long COVID-19 neurocutaneous biosignatures with those of other disorders affecting the sensory and autonomic nervous system.
- Conditions
- Long COVID-19, Acute COVID-19, Postural Orthostatic Tachycardia Syndrome (POTS), Diabetic Neuropathy
- Trial name
- LCCS (NCT07005947)
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- CND Life Sciences
Postural Orthostatic Tachycardia Syndrome, COVID-19
Effects of Individual Tailored Physical Exercise in Patients With POTS After COVID-19 - a Randomized Controlled Study
Covid-19 has the potential to affect physical, cognitive and psychological functions in multiple ways. It has been clear that a significant proportion of patients with Covid-19 develop long-term symptoms.
- Conditions
- Postural Orthostatic Tachycardia Syndrome, COVID-19, Post COVID-19 Condition, Post-Acute COVID-19 Syndrome
- Trial name
- NCT05877534
- Testing
- Individual tailored exercise
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Post-Acute COVID-19 Syndrome
Enhanced External Counterpulsation to Treat Long COVID-19 Fatigue
The goal of this double blind, outcome-assessor blind, randomized controlled trial, is to compare the effectiveness of external encounter counterpulsation (EECP) versus sham procedure in participants with long COVID-19 fatigue.
- Trial name
- EXPECT (NCT05668039)
- Testing
- Enhanced external counterpulsation
- Where
- Israel
- Volunteers
- 32 people
- Sponsor
- Sheba Medical Center
COVID-19, Post-Acute COVID-19
Co-design of a Digital Health Solution to Monitor Persisting Symptoms Related to COVID-19 Using Voice
The UpcomingVoice project aims to co-design a digital health solution based on vocal biomarkers for screening and self-monitoring of frequently reported COVID-19-related symptoms with its end-users: 1) people with persisting…
- Trial name
- UpcomingVoice (NCT05546918)
- Testing
- survey, interviews and focus groups
- Where
- Luxembourg
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
COVID-19 Acute Respiratory Distress Syndrome, Cognitive Decline
Cognitive Functions After COVID-19
This study was aimed to evaluate the post-infection cognitive functions of adult individuals with COVID-19. 50 individuals with COVID-19 and 50 healthy control groups were included in the study.
- Trial name
- NCT04978246
- Testing
- Neuropsychometric Test
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medipol University
Post-Acute COVID-19 Syndrome, Dysautonomia
Post Covid-19 Dysautonomia Rehabilitation Randomized Controlled Trial
Dysautonomia in post-covid-19 condition appears to affect a significant number of patients, with reports raising the incidence up to 61%, having an overlap with myalgic encephalomyelitis/ chronic fatigue syndrome.
- Trial name
- LoCoDiRe-Dys (NCT05855356)
- Testing
- Rehabilitation, Standard of Care
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Evangelismos Hospital
Long COVID, Post-Acute COVID-19 Syndrome
A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid
Purpose: To decrease symptom burden, improve cognitive function, improve endurance, and decrease fatigue in subjects with post-acute sequelae of COVID-19 (PASC) or "long-hauler" COVID using amantadine.
- Trial name
- NCT06234462
- Testing
- Amantadine, Physical, Occupational, Speech Therapy, Provider Counseling
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
COVID-19
The Effects of a Multi-factorial Rehabilitation Program for Healthcare Workers Suffering From Post-COVID-19 Fatigue Syndrome
The SARS-CoV2 pandemic has kept the world in suspense for over a year now. Almost 100 million people around the world have contracted COVID-19 to date and over 2 million people have died of COVID-19 by the end of January 2021.
- Trial name
- NCT04841759
- Testing
- Exercise
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Post-COVID-19 Syndrome, Dyspnea
Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea
To evaluate the extent to which a 12-week respiratory rehabilitation program consisting of inspiratory and expiratory breathing exercises compared to expiratory breathing exercises alone will help to improve shortness of breath…
- Trial name
- NCT06091280
- Testing
- Respiratory Muscle Strength Trainers
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of South Florida
Post-acute Sequelae of SARS-COV-2 Infection
Effect of Apollo Wearable on Long COVID-19 Symptoms.
The purpose of this study is to examine how Apollo wearable use impacts symptoms and quality of life following long COVID.
- Trial name
- NCT06097442
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Board of Medicine
COVID-19
A Study to Understand How the Use of Paxlovid Affected Healthcare Use in People With Pre-existing Conditions.
This is a cohort study that will include Paxlovid (nirmatrelvir-ritonavir) treatment eligible for people with a positive SARS-CoV-2 diagnostic test and at least one COVID-19 symptom.
- Trial name
- NCT07090486
- Testing
- nirmatrelvir-ritonavir
- Where
- United States
- Volunteers
- 14,000 people
- Sponsor
- Pfizer
Covid19, Post-acute Covid-19 Syndrome
Physical Training in Patients With POTS After Covid-19
Covid-19 has the potential to affect physical, cognitive and psychological functions in multiple ways. It has been clear that a significant proportion of patients with Covid-19 develop long-term symptoms.
- Conditions
- Covid19, Post-acute Covid-19 Syndrome, Postural Orthostatic Tachycardia Syndrome
- Trial name
- POTS-ReCOV (NCT05094622)
- Testing
- Physical exercise program
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Long COVID
A Cross-sectional, Observational Study to Characterise Long COVID-19 in an Urban Sample of South African Adults
"Long-COVID'' (also known as post-COVID-19 syndrome, post-acute sequelae of COVID-19, or chronic COVID syndrome, used here as 'Long-COVID' for brevity), is a complex array of postconvalescence symptoms following SARS-CoV-2…
- Trial name
- ChaLOC (NCT05445713)
- Where
- 2 sites in South Africa
- Volunteers
- 400 people
- Sponsor
- University of Witwatersrand, South Africa
ME/CFS, Long COVID
LIFT: Life Improvement Trial
The LIFT will be conducted at Brigham and Women's Hospital (BWH) of Harvard Medical School, focusing on the effect of Pyridostigmine (Mestinon) and Low-Dose Naltrexone (LDN) in subjects aged 18-70 meeting the Canadian consensus…
- Conditions
- ME/CFS, Long COVID, PASC
- Trial name
- LIFT (NCT06366724)
- Testing
- Pyridostigmine, Low-Dose Naltrexone
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
COVID-19, Post-COVID-19 Syndrome
tDCS in Post-COVID Syndrome: Comparison of Two Targets
The main aim of this study is to compare the effect of two non-invasive neuromodulation targets in patients meeting WHO criteria for the post-COVID condition. A randomized, parallel, double-blind study will be conducted.
- Conditions
- COVID-19, Post-COVID-19 Syndrome, Post COVID-19 Condition
- Trial name
- NCT05753202
- Testing
- transcranial current direct stimulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital San Carlos, Madrid
Covid19, SARS CoV 2 Infection
COVID-19: A Scope Research on Epidemiology and Clinical Course
Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) 2 infection and the associated coronavirus disease 2019 (COVID-19) are the most recent international health threat challenging our ability to protect populations, to…
- Conditions
- Covid19, SARS CoV 2 Infection, Sequelae of; Infection
- Trial name
- COVID-Scope (NCT05046769)
- Where
- Portugal
- Volunteers
- 5,000 people
- Sponsor
- Instituto de Saude Publica da Universidade do Porto
Long COVID
Pain in Long COVID-19: The Role of Sleep
Pain is among the most frequently reported symptoms in Long COVID, along with sleep disturbances, fatigue, and cognitive impairments. Sleep plays a critical role in maintaining a pain-free state.
- Trial name
- NCT05606211
- Testing
- No intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Beth Israel Deaconess Medical Center
Depression, Post-COVID-19 Syndrome
Evaluation of DEPREXIL in Patients With Clinical Depression Through Psychological and Neuroendocrine Assessment
Clinical depression is a mood disorder that affects people of all ages with symptoms such as sadness, anger or frustration, appetite changes, difficulty concentrating and suicidal thoughts.
- Conditions
- Depression, Post-COVID-19 Syndrome, Depression Mild, Depression Moderate
- Trial name
- NCT06496087
- Testing
- DEPREXIL
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Catalysis SL
Long COVID
Effect of Lithium Therapy on Long COVID Symptoms
This study will assess low-dose lithium's effects on several different symptoms experienced by long COVID patients.
- Trial name
- NCT05618587
- Testing
- Lithium
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- State University of New York at Buffalo