Clinical trials: Post Acute Sequelae of COVID-19
COVID-19, Musculoskeletal Pain
Musculoskeletal Pain in Long COVID
Long COVID is a new disease, with musculoskeletal pain being one of the common presenting symptoms. This longitudinal study will explore the long COVID musculoskeletal pain aetiology, pathophysiology, impact on function and…
- Trial name
- MUSLOC (NCT05358119)
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Leeds
Long Covid19, Neuropsychiatric Symptom
Acupuncture for Post COVID-19 Condition (Long COVID) Neuropsychiatric Symptoms
In this study, a 12-week pragmatic, randomized, double-blinded clinical trial will be conducted to evaluate the efficacy of acupuncture for the treatment of long Covid neuropsychiatric symptoms and provide reference for clinical…
- Conditions
- Long Covid19, Neuropsychiatric Symptom, Acupuncture
- Trial name
- NCT06633666
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Hong Kong Baptist University
COVID-19
Fascial Tissue Response to Manual Therapy: Implications in Long COVID-19
According to the World Health Organization (WHO), as of mid-September 2022, more than 21 million Brazilians have recovered from COVID-19.
- Trial name
- NCT06348186
- Testing
- Guidebook, Guidebook and Myofascial Reorganization® (RMF).
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
Long COVID, Long Covid19
RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))
This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management…
- Conditions
- Long COVID, Long Covid19, Long Covid-19
- Trial name
- NCT06404073
- Testing
- Structured Pacing, Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Post COVID-19 Syndrome, Functional Inspiratory Muscle Training
Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome
This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome.
- Conditions
- Post COVID-19 Syndrome, Functional Inspiratory Muscle Training, Core Stabilization
- Trial name
- NCT07051954
- Testing
- Core Stabilization, Functional Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Post-Acute COVID-19 Syndrome
Cognitive Rehabilitation Therapy for COVID-19
Cognitive dysfunction, psychiatric symptoms, functional impairment, and disability following COVID-19 negatively impact Veterans' community functioning and quality of life, contribute to significant human suffering, and are…
- Trial name
- CCT-COVID (NCT06086379)
- Testing
- Compensatory Cognitive Training for COVID-19, Holistic Cognitive Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development
Long COVID
Cognitive Impairment and Return to Work in Long COVID
This retrospective, single-center observational study investigates the relationship between cognitive performance and return to work in patients with Long COVID.
- Trial name
- REWORK-COV (NCT07881029)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hopitaux de Saint-Maurice
Long COVID
Health-related Quality of Life and Long COVID
Background: Long COVID is estimated to affect 1.7 million people in the UK. One way of assessing the impact of long COVID is to measure quality-of-life through a standard questionnaire, which can then be used to understand the…
- Trial name
- OpenPROMPT (NCT05552612)
- Where
- United Kingdom
- Volunteers
- 7,574 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Post-COVID-19 Syndrome, Long COVID
Magnesium and Vitamin D Combination for Post-COVID Syndrome
The goal of this double-blind randomized controlled clinical trial is to determine the efficacy of the administration of magnesium chloride + vitamin D as an adjuvant in the treatment of post-Coronavirus Disease (COVID) syndrome.
- Conditions
- Post-COVID-19 Syndrome, Long COVID, Vitamin D Deficiency, Magnesium Deficiency
- Trial name
- NCT05630339
- Testing
- Magnesium chloride, Vitamin D
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Post-COVID Condition, Fatigue Symptom
Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in improving severe fatigue in non-hospitalized adults with symptomatic Post-COVID Condition (PCC) (also called Long COVID).
- Trial name
- CLEAR-LC (NCT06597396)
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Beth Israel Deaconess Medical Center
Post-COVID-19 Syndrome
Rehabilitation Therapy for Post COVID 19 Chronic Fatigue Syndrome
The aim of this study is to investigate the effect of intensive combined rehabilitation therapy in form of Graded Exercise Therapy (GET) , Cognitive Behavioral Therapy (CBT) to treat patients with post COVID19 chronic fatigue…
- Trial name
- NCT05534997
- Testing
- intensive combined rehabilitation therapy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Post-COVID-19 Syndrome, Fatigue Post Viral
Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19 Syndrome
Evaluation of the short- and medium-term effect of a yoga intervention in addition to routine care compared to health education in addition to routine care on fatigue in patients with post covid syndrome.
- Trial name
- YoFaPoCo (NCT05890599)
- Testing
- Yoga Therapy, Health Education
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
COVID-19
Impact of Long COVID-19 on the Health and Quality of Life of Military Personnel (Active or Retired) and Their Families
Severe and sometimes irreversible sequelae are observed in people who have developed a severe form of COVID-19 (pulmonary, cardiovascular, renal, neurological sequelae among others).
- Trial name
- IMP@LA (NCT05200832)
- Testing
- Online questionnaire, Semi-structured interview
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
COVID-19, Long COVID-19
Effects of Physiotherapy Via Telerehabilitation in Patients With COVID-19
This study aims to evaluate the effects of Physiotherapy Via Video Calls on Cardiopulmonary Functions, Physical Function, Cognitive Function, Activity Daily Livings, and Quality of Life in Patients With COVID-19.
- Conditions
- COVID-19, Long COVID-19, Cardiopulmonary Function, Physical Function
- Trial name
- NCT06251011
- Testing
- Exercise training
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Chulabhorn Hospital
Long COVID, Long COVID-19 Syndrome
Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
Post-Covid syndrome, also known as long Covid, is a clinical condition in which patients experience long term symptoms after Covid-19 infection. Treatment options for post-Covid are not effective.
- Conditions
- Long COVID, Long COVID-19 Syndrome, Long Covid19, Long Covid 19
- Trial name
- QoL COVID HBOT (NCT06159309)
- Testing
- Hyperbaric oxygen therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Rutger Lalieu
COVID-19
Exercise Interventions in Post-acute Sequelae of Covid-19
The COVID-19 pandemic severely impacted the medical system both directly but also through incomplete recovery from the virus in the form of post-acute sequelae of COVID-19 (PASC).
- Trial name
- NCT06065033
- Testing
- Exercise
- Where
- United States
- Sponsor
- University of Virginia
Long-COVID
Long-term COVID and Rehabilitation
The proposed focuses on improving both morbidity and mortality in older Veterans and those recovering from COVID-19 by developing rehabilitation therapies to augment vascular endothelial function by combating the oxidative stress…
- Trial name
- NCT05373043
- Testing
- Mitoquinone
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
COVID-19
Prevalence of Long COVID-19 in the Canary Islands
With more than 246 million people diagnosed with coronavirus 2019 (COVID-19) around the world, many of whom have required medical attention for past 23 months, greater emphasis is being placed on post-acute care of COVID-19…
- Trial name
- NCT05228691
- Testing
- Evaluation and Education
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- University of Las Palmas de Gran Canaria
COVID-19
Neuro-inflammation and Post-infectious Fatigue in Individuals With and Without COVID-19
Neuroinflammation can be an important regulator of long COVID, specifically fatigue and cognitive complaints. There is evidence that peripheral inflammation and neuro-inflammation are involved in fatigue and cognitive complaints…
- Trial name
- COVFATI (NCT05371522)
- Testing
- [18F]DPA-714 positron emission tomography (PET) scan
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Long COVID, Myocardial Injury
Resonance Breathing Training for Long Covid-related Myocardial Injury
An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury
- Trial name
- NCT06379672
- Testing
- Resonance breathing
- Volunteers
- 70 people
- Sponsor
- Chengdu Sport University