Clinical trials: Post Cataract Surgery
Senile Cataract
Safety and Performance of Hydrophobic and Hydrophilic Intraocular Lenses After Bilateral Cataract Surgery
Subjects who had a bilateral age-related cataract surgery with the IOLs AT ELANA 841P and AT LISA tri 839MP will be contacted and invited to attend a postoperative visit more than one year after the surgery
- Trial name
- NCT06192901
- Where
- El Salvador
- Volunteers
- 8 people
- Sponsor
- Carl Zeiss Meditec AG
Glaucoma, Cataract
A Comparison of Three Different Formulations of Prednisolone Acetate 1%
Generic prednisolone acetate 1% is less effective than Pred Forte 1% or Econopred Plus 1%.
- Trial name
- NCT00345046
- Testing
- Pred Forte, EconoPred Plus, Prednisolone Acetate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Pharmacological Action
Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract Surgery
This study aims to evaluate the short-term effects and safety of prophylactic intra-vitreal injection of triamcinolone-moxifloxacin combination after cataract surgery.
- Trial name
- NCT05428683
- Testing
- intra-vitreal triamcinolone-moxifloxacin injection after cataract surgery as a prophylactic measures against post-operative endophthalmitis
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Emad Abdel Aal Saliem
Cataract, Pseudoexfoliation Syndrome
Bromfenac to Reduce Inflammation in Patients With Pseudoexfoliation Syndrome After Cataract Surgery
OBJECTIVE To evaluate the efficacy of bromfenac ophthalmic solution 0.09% for reducing postoperative inflammation in eyes with pseudoexfoliation syndrome (PEX) undergoing cataract surgery and receiving standard postoperative eye…
- Trial name
- REPEX (NCT02137161)
- Testing
- Dexamethasone+Tobramycin eye drop, Bromfenac eye drop
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Cataract
Quatera 700 vs. Centurion
Phacoemulsification is the most common treatment for cataract surgery in the developed countries and over the years it gained importance due to several factors: small incision, surgery performed under topical anesthesia - which…
- Trial name
- NCT06225362
- Testing
- Quatera 700, Centurion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract, Vitreoretinal Abnormality
Influence of Different Tamponade Eyes on IOL-capsular Complex
Cataract and vitreoretinal diseases often occur simultaneously or cataract is a predictable consequence of vitreoretinal surgery.A combined surgery called phacovitrectomy, has been proved to be comparably safe and effective…
- Trial name
- NCT05296486
- Testing
- phacovitrectomy surgery with silicone oil tamponade, phacovitrectomy surgery with gas tamponade, phacovitrectomy surgery with balanced saline solution tamponade
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Effect of Cataract Surgery on Corneal Endothelium; About 2 Techniques
Qualitative and Quantitative Endothelium Changes After Cataract Surgery: Ultrasound Phacoemulsification vs Nanolaser Technique
Purpose: The aim of this study was to evaluate corneal endothelial cell density and morphology, central corneal thickness, and best visual acuity using US phacoemulsification or Nanosecond laser technique.
- Trial name
- NCT05886283
- Testing
- phacoemulsification, utrasound phacoemulsification, nanolaser phacoemulsification
- Where
- Tunisia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
High Myopia, Capsular Tension Ring
Influence of Capsular Tension Ring on IOL-capsular Complex After Cataract Surgery in Patients With High Myopia: a Clinical Observation Based on SS-OCT
The IOL-capsular complex is formed after cataract surgery and intraocular lens (IOL) implantation.Early postoperative mechanical wrapping of the anterior and posterior capsules plays a significant role in preventing IOL…
- Trial name
- NCT05095194
- Testing
- Cataract surgery with IOL implantation and with/without capsular tension ring implatation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Wenzhou Medical University
Inflammation
Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery
This is a multicenter, double-masked, randomized, vehicle-controlled, parallel-comparison study conducted at sites in the United States (US) in subjects undergoing routine unilateral cataract extraction and lens replacement…
- Trial name
- NCT06164743
- Testing
- VVN461 Ophthalmic Solution 1.0%, VVN461 Ophthalmic Solution 0.5%, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 91 people
- Sponsor
- VivaVision Biotech, Inc
Cataract
Postoperative Outcome Verification of Discrepant Toric IOL Calculator Recommendations After Cataract Surgery
The goal of this observational study is to learn which toric lens calculator best predicts the astigmatism remaining after cataract surgery in adults who received a TECNIS DIU toric intraocular lens (IOL) at Klinik Hietzing…
- Trial name
- NCT07880249
- Testing
- Standardized Postoperative Outcome Visit, Toric IOL Calculator Pathways (Exposure)
- Volunteers
- 128 people
- Sponsor
- Vienna Hospital Association
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract
Post-Market Clinical Survey of Clareon® IOL AutonoMe™ in Japanese Subjects
This purpose of this survey study is to collect and describe clinical outcomes for the intraocular lens (IOL) delivery performance of Clareon® IOL AutonoMe™ when used in daily practice.
- Trial name
- NCT03824028
- Testing
- Clareon® IOL AutonoMe™ automated preloaded delivery system
- Where
- 3 sites in Japan
- Volunteers
- 384 people
- Sponsor
- Alcon Research
Cataract
Visual Acuity After the Combined Binocular Implantation of +2.5 Diopters and +3.0 Diopters ReSTOR Multifocal Intraocular Lenses.
The objective of this study is to assess the visual outcome after the combined binocular implantation of +2.5 D and +3.0 D apodized diffractive multifocal intraocular lenses.
- Trial name
- NCT02314572
- Testing
- Binocular cataract surgery with phacoemulsification and implantation of multifocal intraocular lenses
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Charite University, Berlin, Germany
Cataract
Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing
This study compares two intraocular lenses, the Softec HD and the Tecnis Z9002, used to replace the natural crystalline lens after cataract extraction.
- Trial name
- NCT01249144
- Testing
- Intraocular Lens (IOL)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lenstec Incorporated
Ocular Discomfort
A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery
The primary objective of this exploratory study is to assess preliminary efficacy and safety of rhNGF when administered as eye drops to patients after cataract and refractive surgery.
- Trial name
- NCT03035864
- Testing
- rhNGF, Vehicle
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Dompé Farmaceutici S.p.A
Inflammation Eye
Bromfenac Versus Dexamethasone After Cataract Surgery
The aim of the study is to compare bromfenac to dexamethasone eye drops to control inflammation after cataract surgery. Inflammation in the anterior chamber of the eye will be measured by a Laser Flare Photometer (LFP).
- Trial name
- BVD (NCT03317847)
- Testing
- Bromfenac 0.09 % Ophthalmic Solution, Dexamethasone 0.1% ophthalmic suspension
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
The Incidence and Risk Factors of Glaucoma After Congenital Cataract Surgery
Correlative Study on Incidence and Risk Factors of Glaucoma-related Adverse Event at Various Durations After Congenital Cataract Surgery
A retrospective chart review of 264 eyes from 177 patients was performed who underwent congenital cataract surgery before the age of 14 years.
- Trial name
- NCT04521907
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Wenzhou Medical University
Lens Implantation, Intraocular
Wavefront Analysis and Contrast Sensitivity After Cataract Surgery With Akreos Advanced Optics Intraocular Lens Implantation
Purpose: To determine whether implantation of an intraocular lens (IOL) with a modified anterior and posterior aspherical surface (Akreos AO, Bausch \& Lomb,Inc) results in reduced ocular aberrations (spherical aberration) and in…
- Trial name
- NCT00863759
- Testing
- implantation of intraocular lens (IOL)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo
Ocular Surface Disease, Dry Eye Syndromes
A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface
study the effect of different concentrations of benzalkonium chloride on the ocular surface of non-dry-eyed patients post cataract surgery.
- Trial name
- NCT06404541
- Testing
- Dexamethasone, tobramycin, netilimicin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Cataract, Phacoemulsification Cataract Surgery
Efficacy and Safety of PRO-155 Versus Nevanac in Post Phacoemulsification
The purpose of this study is to evaluate efficacy and safety of the ophthalmic solution PRO-155 in patients post phacoemulsification.
- Trial name
- NCT01657266
- Testing
- PRO-155, Nevanac
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Laboratorios Sophia S.A de C.V.