Clinical trials: Post Cataract Surgery
Senile Cataract
Corneal Endothelial Cell Loss After Phacoemulsification Compared With Extracapsular Cataract Extraction
the investigators will compare between the endothelial cell loss after phacoemulsification and extracapsular cataract extraction in management of senile cataract
- Trial name
- NCT03262285
- Testing
- phacoemulsification, extracapsular cataract extraction
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Cataract
Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing
This study compares two intraocular lenses, the Softec HD and the Tecnis Z9002, used to replace the natural crystalline lens after cataract extraction.
- Trial name
- NCT01249144
- Testing
- Intraocular Lens (IOL)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lenstec Incorporated
Cataract
No Drop Post-Op Cataract Surgery
This study evaluates the effect of Intraocular Phenylephrine/Ketorolac Infusion on Retinal Thickness and Macular Edema in Cataract Surgery.
- Trial name
- NCT03864133
- Testing
- Omidria
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Wake Forest University Health Sciences
Cataract, Phacoemulsification
Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery
To study correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.
- Trial name
- ECOCHI (NCT03972670)
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Cataracts
Endothelial Cell Loss After Phacoemulsification Intra and Supracapsular
Cataract is the clouding of the lens of the eye, which initially prevents clear vision and eventually progresses to blindness if left untreated.
- Trial name
- PERCEPOLIS (NCT02535819)
- Testing
- Subluxation, Divide and Conquer
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Ophthalmology
Optimizing the Ocular Surface With Systane COMPLETE Pre- and Post-operatively in Patients With Dry Eye Planning for Cataract Surgery: An Extension Study of Optimizing the Ocular Surface With Systane COMPLETE in Patients With Dry Eye Planning for Cataract Surgery
Compare the corneal astigmatism data before and after the use of Systane COMPLETE to evaluate its impact on predicting changes in postoperative residual astigmatism, as well as the effects of using or not using Systane COMPLETE…
- Trial name
- NCT06886373
- Testing
- Systane Complete
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- National Taiwan University Hospital
Dry Eye, Vision Disorders
Visual Quality Change of Eyes Implanted With Diffractive Multifocal Intraocular Lens After Cataract Surgery
In this study, the investigators examined the subjective visual quality including LogMAR uncorrected distance visual acuity (UCDVA), best corrected distance visual acuity (BCDVA),uncorrected intermediate visual acuity (UCIVA)…
- Conditions
- Dry Eye, Vision Disorders, Quality of Life
- Trial name
- NCT02234635
- Testing
- Diffractive multifocal IOLs group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wenzhou Medical University
Inflammation Eye
Bromfenac Versus Dexamethasone After Cataract Surgery
The aim of the study is to compare bromfenac to dexamethasone eye drops to control inflammation after cataract surgery. Inflammation in the anterior chamber of the eye will be measured by a Laser Flare Photometer (LFP).
- Trial name
- BVD (NCT03317847)
- Testing
- Bromfenac 0.09 % Ophthalmic Solution, Dexamethasone 0.1% ophthalmic suspension
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Cataract, Endophthalmitis
The Effect of Intracameral Cefuroxime on Post-op Fibrin in Pediatric Cataract Surgery
The study investigates whether placing an antibiotic inside the eye at the end of cataract surgery in children will reduce the amount of fibrin formation (fibrin formation can block the pupil and reduce vision).
- Trial name
- NCT00730938
- Testing
- cefuroxime
- Where
- Kenya
- Volunteers
- 45 people
- Sponsor
- Presbyterian Church East Africa Kikuyu Hospital
Inflammatory Reaction Due to Ocular Lens Prosthesis
Efficacy and Safety Study of IBI-10090 in Patients Undergoing Cataract Surgery
This study will test the efficacy and safety of IBI-10090 for the reduction of ocular inflammation after cataract surgery.
- Trial name
- NCT01048593
- Testing
- IBI-10090
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- ICON Bioscience Inc
Adverse Events
ReSure Sealant Post Approval Study
This is a prospective multicenter observational post-approval registry study that will collect post-approval data relative to the incidence of pre-specified Adverse Ocular Events for cataract surgery patients treated with the…
- Trial name
- Clinical PAS (NCT02310815)
- Testing
- ReSure Sealant
- Volunteers
- 626 people
- Sponsor
- Ocular Therapeutix, Inc.
Dry Eye
SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
Patient: Tear film issues resulting in poor visual outcomes are a major cause of dissatisfaction after cataract surgery. There is no universal best preoperative algorithm for managing the ocular surface prior to surgery.
- Trial name
- NCT07323264
- Where
- Singapore
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Louis Tong
Dry Eye
Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery
The objective of this study is to evaluate the efficacy of Diquafosol 3% in the management of dry eyes before and after cataract surgery.
- Trial name
- NCT04952987
- Testing
- Diquafosol
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Mun Wai Lee
Refractive Errors
Correction of Refractive Error Surprises After Cataract Surgery in Adults
A refractive surprise can be defined as the failure to achieve the intended postoperative refractive target or the presentation of unexpected and, unwanted post-operative refractive error.
- Trial name
- NCT06379477
- Testing
- Refractive surgeries
- Volunteers
- 63 people
- Sponsor
- Assiut University
Myopia, Hyperopia
Accuracy of IOLMASTER 700 Total Keratometry (TK)
This is a multicenter study to compare the accuracy of IOL calculations in post-laser vision corrected eyes that are about to undergo or have undergone cataract surgery.
- Conditions
- Myopia, Hyperopia, Cataract
- Trial name
- NCT05254587
- Testing
- IOLMASTER 700 TK
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- Advanced Vision Care
Intraocular Pressure Low
Effect of Hyaluronidase on Intraocular Pressure
The aim of this study is to evaluate effect of retrobulbar local anaesthesia after addition of hyaluronidase on IOP during cataract surgery
- Trial name
- NCT03266406
- Testing
- Hyaluronidase
- Volunteers
- 50 people
- Sponsor
- Assiut University
Lens Implantation, Intraocular
Wavefront Analysis and Contrast Sensitivity After Cataract Surgery With Akreos Advanced Optics Intraocular Lens Implantation
Purpose: To determine whether implantation of an intraocular lens (IOL) with a modified anterior and posterior aspherical surface (Akreos AO, Bausch \& Lomb,Inc) results in reduced ocular aberrations (spherical aberration) and in…
- Trial name
- NCT00863759
- Testing
- implantation of intraocular lens (IOL)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo
Ocular Inflammation and Pain
Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery
To evaluate the safety and efficacy of OTX-DP as a sustained release drug (dexamethasone) depot when placed in the canaliculus of the eyelid for the treatment of ocular inflammation and pain in subjects who have undergone…
- Trial name
- NCT01666210
- Testing
- OTX-DP (Dexamethasone punctum plug)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ocular Therapeutix, Inc.
Ocular Inflammation and Pain After Cataract Surgery
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery Including a Corneal Endothelial Cell Sub-study
This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion.
- Trial name
- NCT04810962
- Testing
- APP13007, 0.05%
- Where
- 31 sites in United States
- Volunteers
- 370 people
- Sponsor
- Formosa Pharmaceuticals, Inc.