Clinical trials: Post Cataract Surgery
Cataract, Exfoliative Glaucoma
Measurement of Ocular Tensional Fluctuation by Triggerfish Lens Before and After Cataract Surgery in Patients With Exfoliative Glaucoma
Glaucoma is a very frequent disease in Brittany. In glaucoma the retinal ganglion cells and their axons slowly die with visible changes at the optic nerve head (cupping).
- Trial name
- TRIGGERFISH (NCT02658071)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Cataract
Comparison Between Low-Dose and High-Dose Nepafenac Sodium
In South Punjab, Pakistan, where tertiary hospitals manage a high cataract workload, data on nepafenac sodium to reduce this inflammatory response is not up to the mark.
- Trial name
- NCT07749027
- Testing
- Nepafenac sodium (High-dose ), Nepafenac sodium (Low-dose )
- Where
- Pakistan
- Volunteers
- 176 people
- Sponsor
- Muhammad Aamir Latif
Cataract, Age-related Cataract
Association Between Light Spectrum and Survival After Cataract Surgery
This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type…
- Conditions
- Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma
- Trial name
- NCT04187157
- Testing
- Blue-light filtering intraocular lens, Conventional intraocular lens
- Where
- United States
- Volunteers
- 10,192 people
- Sponsor
- University of Pittsburgh
Cataract Patients
Evaluation of Tear Film Lipid Layer Thickness Change After Cataract Surgery
This study will compare cataract patients before and after phacoemulsification. Evaluations will be performed before and 1 and 3 months following cataract surgery, including measurement of tear film lipid layer thickness, tear…
- Trial name
- NCT02567565
- Testing
- LipiView
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Cataract
Comparison of AC and PC Lenses After Vitreous Loss During ECCE
Objective: The standard definition of failure in cataract surgery is best corrected visual acuity of less than 20/40 at one year.
- Trial name
- NCT00453011
- Testing
- posterior chamber intraocular lens, anterior chamber intraocular lens
- Volunteers
- 1,202 people
- Sponsor
- VA Office of Research and Development
Cataract
Optimizing the Assessment of Refractive Outcomes After Cataract Surgery
The purpose of this study is to evaluate current available assessments (automated vs. manual) with which manifest refraction data and biometric variables are obtained to understand if data from an automated refractor can be…
- Trial name
- NCT02842151
- Testing
- Manifest refraction, ACRYSOF® IQ Monofocal IOL Model SN60WF, Topcon® KR-1W Wave-Front Analyzer
- Volunteers
- 162 people
- Sponsor
- Alcon Research
Microphthalmos With Congenital Cataracts
Long-term Postoperative Outcomes After Bilateral Congenital Cataract Surgery in Eyes With Microphthalmos
Cataract surgery in infantile eyes, which are microphthalmic, can be even more demanding. In addition, the frequent presence of other ocular and systemic anomalies such as nystagmus, glaucoma, amblyopia, and higher rate of…
- Trial name
- NCT01818037
- Testing
- Cataract surgery
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
The objective of the study was to evaluate the safety and efficacy of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of post-surgical inflammation and…
- Trial name
- NCT02736175
- Testing
- Dexamethasone
- Volunteers
- 438 people
- Sponsor
- Ocular Therapeutix, Inc.
Secondary Cataract Surgery, Aphakia
Comparison of Two Different Intraocular Lenses Implanted With Yamane Technique
In case of instability or rupture of capsular bag occurs during cataract surgery, Yamane technique is one of the options to fix intracocularlens' haptics.
- Conditions
- Secondary Cataract Surgery, Aphakia, Complicated Cataract Surgery
- Trial name
- NCT05912829
- Testing
- IOL Master 700, Casia-2, MS-39
- Where
- 2 sites in Austria
- Volunteers
- 50 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Presbyopia
Multifocal Intraocular Lens x Monovision x Hybrid Monovision After Bilateral Cataract Surgery
To compare refractive outcomes and patient's visual quality after bilateral cataract surgery when implanting multifocal intraocular lens, monofocal with monovision or hybrid monovision.
- Trial name
- NCT02595177
- Testing
- Cataract surgery with intraocular lens implantation.
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cataract, Intraocular Lens Implant
Quality of Life Evaluation After Cataract Surgery Using 4 Types of Intraocular Lens Implant Combinations
This is multicenter, prospective, comparative and randomized study focusing on the evolution of the quality of Life and Uncorrected Binocular Visual Acuity (UBVA) evaluation at 3 months after cataract surgery in patients who…
- Trial name
- ELVIRA4 (NCT05376917)
- Testing
- Zeiss CT Asphina / Zeiss CT Asphina, Zeiss AT Lara/ Zeiss AT Lisa Tri, Zeiss CT Asphina/ Zeiss AT Lara
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Cataract
Visual Outcomes After Cataract Surgery: Multifocal AcrySof® IQ ReSTOR® Intraocular Lenses Versus Monofocal Intraocular Lenses
The purpose of this study is to assess and compare visual outcomes of the AcrySof® IQ ReSTOR® +3.0 D intraocular lens (IOL) to a commercially available monofocal IOL in cataract patients.
- Trial name
- NCT01290068
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL, Monofocal IOL
- Volunteers
- 208 people
- Sponsor
- Alcon Research
Cataract, Age-related Cataract
Optometric Follow-up After Cataract Surgery
This study will investigate the effectiveness of an optometric follow up of cataract surgery versus an ophthalmic surgeon follow up. It will investigate patient satisfaction,safety and cost.
- Trial name
- NCT04163926
- Testing
- Intervention Group cataract follow up, Usual Care consultant follow up
- Sponsor
- Queen's University, Belfast
Refractive Errors
Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery
To determine if the intraocular pseudophakic contact lens (IOPCL), referred to as the AccuraSee, corrects residual refractive errors after cataract surgery using a plus powered lens in subjects with ocular pathology previously…
- Trial name
- NCT05113979
- Testing
- AccuraSee IOPCL with +3.0D add
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- OnPoint Vision Inc
Cataract Surgery, Ocular Infections
Efficacy of EPD-09-25 for Eyelid Hygiene Before and After Eye Surgery.
This is an interventional, open-label, two-arms clinical trial, randomized 1:1 (EPD treatment or no eyelid hygiene treatment) in patients scheduled for eye surgery (cataract surgery).
- Trial name
- NCT07418333
- Testing
- EPD Eyelid wipes
- Volunteers
- 100 people
- Sponsor
- VISUfarma SpA
Capsular Bag Distention Syndrome After Cataract Surgery
A Retrospective Study to Investigate Prevalence of Capsular Bag Distention Syndrome and Its Influencing Factors
To Investigate the Prevalence of Capsular Bag Distention Syndrome To Analyze Influencing Factors of Capsular Bag Distention Syndrome
- Trial name
- NCT01868217
- Volunteers
- 239 people
- Sponsor
- Evidence Based Cataract Study Group
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Glaucoma, Open-Angle
A Post-market Study Of Use Of The OMNI® Surgical System In Open Angle Glaucoma
To prospectively compare the clinical effect of the OMNI surgical system in eyes with Open Angle Glaucoma.
- Trial name
- NCT04616573
- Testing
- OMNI® Surgical System, iStent inject
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Sight Sciences, Inc.
Treatment of Ocular Inflammation Associated With Cataract Surgery
Study Title: Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (Nepafenac Ophthalmic Suspension) 0.3% QD With Extra (Pulse) Dose on Day of Surgery for Treatment of Ocular Inflammation Associated With Cataract Surgery in a Randomized, Single Masked Clinical Trial
Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (nepafenac Ophthalmic Suspension) 0.3% QD with extra (pulse) dose on day of surgery for Treatment of Ocular Inflammation Associated with Cataract…
- Trial name
- NCT03886779
- Testing
- Bromfenac, Nepafenac
- Volunteers
- 57 people
- Sponsor
- Silverstein Eye Centers
Ocular Inflammation and Pain After Cataract Surgery
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery Including a Corneal Endothelial Cell Sub-study
This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion.
- Trial name
- NCT04810962
- Testing
- APP13007, 0.05%
- Where
- 31 sites in United States
- Volunteers
- 370 people
- Sponsor
- Formosa Pharmaceuticals, Inc.