Clinical trials: Post Cesarean Pain Management
Analgesia
Efficacy of Trans Abdominis Plane Block for Post Cesarean Delivery Analgesia
Relief from pain is part of the fundamental human right to health. (1) However, available evidence indicates an increasingly detailed understanding of the pathophysiology of pain and general inadequacy of its treatment.
- Trial name
- NCT06556381
- Testing
- TAP block
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- Qassim University
Cesarean Section, Postoperative Pain
Ketamine for Analgesia After Cesarean Section
In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.
- Trial name
- NCT04545801
- Testing
- 0.25 mg/kg of Ketamine, 20ml of normal saline solution
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Pain, Postoperative
Cesarean Delivery and Post-operative Pain Management With Local Anesthesia
The use of .5% Bupivacaine with epinephrine at the time of skin closure in cesarean deliveries will decrease post-op pain.
- Trial name
- NCT00298571
- Testing
- .5% bupivacaine with epinephrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Post-Dural Puncture Headache
The Influence of Needle Diameter on Post Dural Puncture Headache
The purpose of this study is to determine whether injection needle pen point type 'PP Gauge 25' should be recommended as a primary choice of needle (in stead of 'PP Gauge 27') for healthy pregnant women who at delivery (vaginal…
- Trial name
- NCT02827058
- Testing
- G25 pencil point needle, G27 pencil point needle
- Where
- 3 sites in Norway
- Volunteers
- 65 people
- Sponsor
- Helse Nord-Trøndelag HF
Pain, Cesarean Section
Intrathecal Hydromorphone for Pain Control After Cesarean Section
The use of intrathecal opioids for analgesia in the setting of cesarean section has become standard obstetric anesthesia practice. Currently, two opioids are commonly used. These opioids are fentanyl and morphine (Duramorph).
- Trial name
- NCT02096003
- Testing
- Intrathecal morphine, Intrathecal hydromorphone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Analgesia
Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block
The objective of this study is to compare the efficacy of transversalis fascia plane block using bupivacaine and ketamine versus bupivacaine alone for pain management after cesarean section under spinal anaesthesia.
- Trial name
- TFBP (NCT06935669)
- Testing
- Ketamine, Bupivacaine, Bupivacain
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cesarean Section, Pain, Acute
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
The investigators are comparing post operative analgesia provided for caesarean section patients, with the quadratus lumborum type 2 block and intrathecal morphine.
- Trial name
- NCT03267628
- Testing
- Intrathecal morphine as well as local anaesthetic in Blocks, Intrathecal morphine as well as saline in Block, Saline intrathecal as well as saline in Blocks
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr Willem Basson
Cesarean Section, Epidural; Anesthesia
Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor
The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia.
- Trial name
- NCT04074005
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Postoperative Analgesia, Cesarean Section
Postoperative Analgesia After Cesarean Section; Comparison Among Ultrasound Guided Erector Spinae, Quadratus Lumborum or Transversus Abdominis Plane Blocks
The aim of this prospective randomized controlled study is to compare the analgesic efficacy of the ultrasound-guided erector spinae plane block, ultrasound-guided quadratus lumborum plane block, and ultrasound-guided transversus…
- Conditions
- Postoperative Analgesia, Cesarean Section, Erector Spinae Block, Quadratus Lumborum Block
- Trial name
- NCT06451354
- Testing
- Erector spinae plane block (20 ml bupivacaine 0.25% in each side), Posterior Quadratus lumborum plane block (20 ml bupivacaine 0.25% in each side), Lateral Transversus abdominis plane block (20 ml bupivacaine 0.25% in each side)
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Kafrelsheikh University
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Pain, Postoperative, Obesity
TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia
Cesarean deliveries are the most commonly performed surgery in the United States and account for 32.9% of all births.8,9 The ASA recommends the use of neuraxial opioids of post-cesarean analgesia partly because respiratory…
- Conditions
- Pain, Postoperative, Obesity, Respiratory Insufficiency
- Trial name
- NCT03282669
- Testing
- Intrathecal Morphine, Intravenous hydromorphone
- Sponsor
- Northwestern University
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Other Chronic Postoperative Pain
High Pain Intervention in Cesarean Sections
In previous studies the investigators have seen that the severity of pain one day after cesarean delivery can predict the presence of pain and depression 2 months later.
- Trial name
- NCT01298778
- Testing
- Duramorph 150, Acetaminophen, Duramorph 300
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Postoperative, Opioid Use
Management Of Pain After Cesarean Trial
This is a double blinded randomized controlled trial to test the efficacy of a combination of acetaminophen and ibuprofen administered to patients on schedule compared to ibuprofen alone on the patient's reported pain score on…
- Trial name
- MOPAC (NCT03929640)
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Milton S. Hershey Medical Center
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Cesarean Section
Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section
The purpose of this randomized double-blind study is to evaluate in which anatomical layer (AF versus BF) continuous wound infusion of local anesthetics combined with NSAIDs through a multiorifice catheter has the best…
- Trial name
- NCT01160913
- Testing
- Continuous wound infusion, Continuous wound
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Association pour la Recherche et la Formation en Anesthésie Analgésie Réanimation
Labor Pain, Post-cesarean Delivery
Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia
Pharmacogenetics has allowed clinicians to identify associations between an individual's genetic profile and his/her response to drugs.
- Trial name
- NCT00418015
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cesarean Section Complications
The Efficacy of Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery:
This study aimed to compare bilateral ultrasound-guided TAP block with single-shot local anesthetic wound infiltration for analgesia after cesarean delivery performed under spinal anesthesia
- Trial name
- TAPBLOCK (NCT04874168)
- Testing
- TAP block
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Ain Shams University
Pain Management in Adult Females in Child Bearing Period Aging From 20 to 45 Years Who Are Scheduled for Elective Cesarean Section
Intrathecal Dexmedetomidine Versus Transversus Abdominus Plane Block (TAP) for Postoperative Analgesia After Cesarean Section.
Spinal anesthesia is the most commonly used technique for lower abdominal surgeries as it is very economical and easy to administer.
- Trial name
- NCT04969705
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postpartum Women
The Effects of Acupressure on Pain After Cesarean Section
Purpose: To examine the effect of Pericardium 6 and Large Intestine 4 acupressure on pain and analgesia consumption in women after cesarean section.
- Trial name
- NCT04337801
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Akdeniz University