Clinical trials: Post Covid Syndrome
Long COVID-19 Syndrome, Long COVID
Feasibility and Preliminary Efficacy of a Group-based Telerehabilitation Program in People With Post-COVID-19 Sequelae (TEPCO).
The goal of this study pilot randomized controlled study is to evaluate the feasibility of the study procedures and to compare the preliminary efficacy of a rehabilitation program given in a "remote" (telerehabilitation) or…
- Conditions
- Long COVID-19 Syndrome, Long COVID, Long COVID Syndrome
- Trial name
- TEPCO (NCT06952127)
- Testing
- Rehabilitation program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec
Post COVID-19 Condition
Pilot Open Label Use of the Hi-OXSR for the Treatment of Post COVID-19 Cognitive Dysfunction
During the worldwide COVID-19 pandemic a large number patients reported different functional complaints one month or later after recovery from the acute infection.
- Trial name
- Hi-OXSR (NCT06379620)
- Testing
- Hi-OxSR Sequential Rebreathing mask (oxygen concentrator)
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- University Health Network, Toronto
Long COVID-19, Post-COVID-19 Syndrome
Effects of a Home-Based Exercise Intervention in Subjects with Long COVID
The current Coronavirus Disease 2019 (COVID-19) pandemic is the most severe health crisis of the 21st century. This is not only due to the deaths caused by the disease.
- Trial name
- NCT06073002
- Testing
- home-based concurrent exercise
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- University of Vienna
Coronavirus Disease 2019 (COVID-19), Post-Exposure Prophylaxis
Hydroxychloroquine Post-Exposure Prophylaxis for Coronavirus Disease (COVID-19) Among Health-Care Workers
Background: The rapid spread and high infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) makes identifying an effective prophylaxis agent highly important.
- Trial name
- NCT04438837
- Testing
- Hydroxychloroquine
- Where
- Israel
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Post-Acute COVID-19 Syndrome, COVID-19
Long COVID-19 Rehabilitation & Recovery Research Program
The purpose of the study is to assess the physiologic, immunologic, and mental health effects of an exercise and pulmonary rehabilitation program on patients with Long COVID-19 (LC).
- Trial name
- LC Rehab (NCT05398692)
- Testing
- On Site Exercise Rehabilitation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Multiple Sclerosis, Long COVID
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
This study is for people who have multiple sclerosis, acute leukemia (in remission), or long-COVID and a Body Mass Index over 27 and may struggle with cognitive issues such as remembering information, concentrating, or making…
- Conditions
- Multiple Sclerosis, Long COVID, Long Covid19, Obese
- Trial name
- NCT06171152
- Testing
- Liraglutide Pen Injector [Saxenda], Medication Diary
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
COVID-19
Mechanisms Underlying Cardiovascular Consequences Associated With COVID-19 and Long COVID
AIM 1. Characterize cardiovascular phenotypes of long COVID by cardiopulmonary, meta-bolic, and cardiac mechanical/physiological responses to exercise and microvascular vasomotor function. AIM 2.
- Trial name
- NCT06427512
- Where
- United States
- Sponsor
- Columbia University
Post COVID-19 Condition, Post-COVID-19 Syndrome
The COPE Study: Pilot Intervention to Improve Symptom Self-management and Coping in Adults With Post COVID-19
This project is a randomized controlled pilot trial using mixed methods to examine the feasibility, acceptability, and initial effects of a telemedicine group-based intervention designed to improve symptom management and coping…
- Trial name
- NCT05658536
- Testing
- 6-Week Self-Management Group
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Washington
Long COVID
Biosound Therapy as a Treatment for Long COVID Patients
This study aimed to explore the impact of the Biosound Therapy Systerm on long COVID symptoms while determining feasibility of a future full-scale Randomized Controlled Trial.
- Trial name
- NCT05848401
- Testing
- Biosound Therapy System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Anxiety Relief Center
Post-acute COVID-19 (PACS), or "long COVID" Syndrome
Impact of Monoclonal Antibody Treatment on Post-Acute COVID-19 Syndrome
Use the Intermountain real-world MAb-treatment registry and control group to prospectively evaluate PACS symptoms at least 60 days after initial COVID-19 diagnosis.
- Trial name
- MAbPACs (NCT05013723)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Intermountain Health Care, Inc.
Kidney Transplant Recipients, Liver Transplant Recipients
COVID Protection After Transplant-Immunosuppression Reduction
This study will enroll individuals who have: Completed primary series of mRNA COVID-19 vaccine, and An antibody response ≤ 2500 U/mL measured at least 30 days after the last dose of vaccine.
- Trial name
- CPAT-ISR (NCT05077254)
- Testing
- Pfizer-BioNTech COVID-19 Vaccine 2023-2024, Moderna COVID-19 Vaccine 2023-2024, SOC IS Regimen
- Where
- 15 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Post-COVID Condition, Long COVID
Long-Term Health Effects of Previous Coronavirus Disease 2019 (COVID-19) in Patients Undergoing Preoperative Anesthesia Evaluation
The Coronavirus Disease 2019 (COVID-19) pandemic has resulted in persistent health problems in a significant proportion of individuals after recovery from the acute infection.
- Conditions
- Post-COVID Condition, Long COVID, Sequelae of COVID-19
- Trial name
- NCT07435805
- Testing
- Post-COVID Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Long COVID, Breathlessness
Long COVID and Post-exertional Pulmonary Diffusion
Aim of investigators was to study whether abnormalities of lung diffusing capacity for nitric oxide (DLNO) and carbon monoxide (DLCO) in long COVID may have a clinical impact in relation to exercise intolerance.
- Conditions
- Long COVID, Breathlessness, Exercise Intolerance, Alveolar Lung Disease
- Trial name
- Long_COVID_Ex (NCT05430503)
- Testing
- Lung volumes, spirometry and standard single-breath DLCO were measured at rest while combined DLNO and DLCO were measured at rest and post-exercise
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Long COVID
Qigong for Post Acute Sequelae of COVID-19 Infection
The purpose of this study is to conduct a pilot feasibility study of a combination of external and internal qigong on health-related quality of life in individuals with prolonged symptoms following COVID-19 infection.
- Trial name
- NCT05675995
- Testing
- Qigong
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Long COVID, Long COVID Syndrome
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation
The goal of this clinical trial is to test whether a type of rapid outpatient brain stimulation that uses magnetic fields, called accelerated intermittent theta burst stimulation (iTBS), can treat symptoms such as brain fog…
- Conditions
- Long COVID, Long COVID Syndrome, Long COVID-19 Syndrome, PASC
- Trial name
- MANIFEST (NCT06940609)
- Testing
- accelerated intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Long COVID, Post Acute Sequelae of COVID-19
PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 have long-term symptoms that affect the brain.
- Trial name
- NCT06920628
- Testing
- 11C-PS13
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Long COVID, Chronic Fatigue Syndrome
Telerehabilitation for Post COVID-19 Condition
Telerehabilitation is a great alternative to offering care during a global pandemic. 85% of patients with COVID-19 report persistent symptoms up to 8 months after the infection.
- Trial name
- Telecovie (NCT05973136)
- Testing
- Telerehabilitation program based on cardiorespiratory principles
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Université de Sherbrooke
Post-Acute COVID19 Syndrome, Fatigue
Feasibility Study of Adhera® Fatigue Digital Program for Patients With Long COVID-related Fatigue
Adhera® Fatigue Digital Program (or AFDP) is a digital health program based on behavioral and emotional change techniques that provides personalized physical and emotional self-management support for patients with long…
- Trial name
- COVIDAI (NCT05631171)
- Testing
- Adhera® Fatigue Digital Program
- Where
- 2 sites in Spain
- Volunteers
- 58 people
- Sponsor
- Adhera Health, Inc.
Post-COVID-19 Syndrome
Prednisolone and Vitamin B1/6/12 in Patients With Post-Covid-Syndrome
This is a multicenter, randomized, placebo controlled, double-blind phase III trial with four parallel groups studying studying the feasibility of RCT in primary care as well as the effectiveness of treatment with prednisolone…
- Trial name
- PreVitaCOV (NCT05638633)
- Testing
- Prednisolone 20 mg/ 5 mg, Vitamin B compound (100mg B1, 50 mg B6, 500 µg B12)
- Where
- 3 sites in Germany
- Volunteers
- 321 people
- Sponsor
- Wuerzburg University Hospital
Long COVID
Neurobiological Underpinnings of Neuropsychological Consequences in Long COVID
Objectives: To describe the standardized evaluation of the psychological and cognitive function of long COVID patients and their evolution, to compare immunological and HPA-axis related biomarkers between long COVID patients and…
- Trial name
- Cov-N-Psy (NCT06279936)
- Testing
- Neuropsychological battery, Surveys and symptom severity questionnaires, Blood withdrawal
- Where
- Belgium
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen