Clinical trials: Post Covid Syndrome
Post-COVID Condition, Fatigue Symptom
Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in improving severe fatigue in non-hospitalized adults with symptomatic Post-COVID Condition (PCC) (also called Long COVID).
- Trial name
- CLEAR-LC (NCT06597396)
- Testing
- Abrocitinib
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Beth Israel Deaconess Medical Center
Long Covid
Antiviral Clinical Trial for Long Covid-19
The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants with Long Covid compared to placebo. Viral infection and viral reactivation have been documented in Long Covid.
- Trial name
- NCT06511063
- Testing
- tenofovir disoproxil/emtricitabine, Selzentry
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post COVID-19 Condition, Long COVID
Pycnogenol® in Post-COVID-19 Condition
To determine the effect of Pycnogenol® versus placebo on patient-reported health status in people with post COVID-19 condition.
- Trial name
- PYCNOVID (NCT05890534)
- Testing
- Pycnogenol®
- Where
- Switzerland
- Volunteers
- 153 people
- Sponsor
- University of Zurich
Long COVID, Chronic Pain
Characterization of Long Covid Pain in Primary Care
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Prevalence data and the underlying mechanisms of such pain are very limited in the scientific literature.
- Conditions
- Long COVID, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT05894642
- Testing
- 0
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Post-COVID-19 Syndrome, Post-COVID Syndrome
Post-COVID-19 Chronic Fatigue Syndrome
Fatigue is recognized as one of the most commonly presented long-term complaints in individuals previously infected with SARS-CoV-2.
- Trial name
- NCT05642923
- Testing
- Synthetic Vitamin B1
- Where
- Egypt
- Volunteers
- 528 people
- Sponsor
- ClinAmygate
Long COVID, Postural Orthostatic Tachycardia Syndrome
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can…
- Conditions
- Long COVID, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Myalgic Encephalomyelitis
- Trial name
- NCT05741112
- Testing
- Wearable device
- Where
- United States
- Volunteers
- 100,500 people
- Sponsor
- Scripps Translational Science Institute
Long COVID, Respiratory Disease
Cognitive Muscular Therapy for Patients With Long-COVID and Breathing Pattern Disorder
The aim of the study is to test a treatment known as "Cognitive Muscular Therapy (CMT)" for reducing breathlessness and improving autonomic function in patients with long-COVID.
- Trial name
- COMLOC (NCT06503913)
- Testing
- Cognitive Muscular Therapy, Breathing visualisation
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Salford
Covid 19
Study to Evaluate Benefits & Safety of Endourage Formula C™ Oral Drops in People With Post-Acute COVID-19 Syndrome.
This study will explore the contribution of CBD oral drops in persons experiencing symptoms of Post Acute COVID Syndrome or "PACS".
- Trial name
- "BAC-PAC" (NCT04828668)
- Testing
- Targeted Wellness Formula C™ Sublingual Drops - 1200mg - 30 mL (Formula C)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Endourage, LLC
Covid19, Corona Virus Infection
Clinical, Functional, Immunological and Genetic Factors on the Severity of the Course of Coronavirus Infection
The purpose of the program. To determine the clinical, functional, immunological, and genetic factors affecting the severity of the course of acute coronavirus infection COVID-19 and PostCovid syndrome, in order to develop…
- Trial name
- NCT04987853
- Testing
- Clinical and functional analysis, Neurological analysis, Immunological analysis:
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- National Research Center for Cardiac Surgery, Kazakhstan
PASC Post Acute Sequelae of COVID 19
Physiological and QoL Benefits of Qi-Gong in Post-acute Sequelae of Covid-19
The goal of this clinical trial is to determine whether Qi-Gong can improve physiological function and quality of life (QoL) in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC).
- Trial name
- QG-PASC (NCT06879925)
- Testing
- QI-GONG and control
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- POCHIWU
Long COVID, Long Covid19
RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management…
- Conditions
- Long COVID, Long Covid19, Long Covid-19
- Trial name
- NCT06404060
- Testing
- Personalized Cardiopulmonary Rehabilitation, Education
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Duke University
Post Acute COVID 19 Syndrome, Memory Impairment
HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)
The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with Post Acute Covid Syndrome (PACS).
- Conditions
- Post Acute COVID 19 Syndrome, Memory Impairment, Memory Dysfunction, Cognitive Dysfunction
- Trial name
- NCT06391489
- Testing
- HOBSCOTCH-PACS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Long COVID, Myocardial Injury
Resonance Breathing Training for Long Covid-related Myocardial Injury
An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury
- Trial name
- NCT06379672
- Testing
- Resonance breathing
- Volunteers
- 70 people
- Sponsor
- Chengdu Sport University
COVID-19, Long COVID
A Six-Month Follow-Up Study of Participants With Coronavirus Disease 2019 (COVID-19) Previously Enrolled in a RO7496998 (AT-527) Study
This study will evaluate the long-term sequelae of COVID-19 in patients diagnosed with COVID-19 who previously enrolled in a RO7496998 (AT-527) study (i.e.
- Trial name
- MEADOWSPRING (NCT05059080)
- Where
- 35 sites in Argentina, Belgium and 8 more
- Volunteers
- 72 people
- Sponsor
- Hoffmann-La Roche
Long COVID, Dysautonomia
Mindfulness in Post Acute Sequelae of SARS-CoV-2 Infection (PASC) Dysautonomia
The current pilot study will recruit participants experiencing new, returning, or ongoing symptoms related to COVID-19 illness for at least four weeks after being first infected with SARS-CoV-2.
- Trial name
- NCT05566379
- Testing
- Mindfulness - Mindful Awareness Practices ( MAPs)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Long COVID, Pain
Pain Relief With Integrative Medicine (PRIMe)?: Feasibility of Acupuncture for Long COVID
The goal of this preliminary study is to test methods and procedures to be used in a fully-powered trial to evaluate acupuncture treatment effectiveness.
- Trial name
- NCT06476496
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Washington
Fatigue, Post-Acute COVID-19 Syndrome
Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome
The complex clinical symptoms of post COVID syndrome, especially chronic fatigue, pose a major challenge to patients and to the health care system and are frequently refractory to therapeutic intervention.
- Trial name
- NCT05954325
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Hannover Medical School
Post-acute Sequelae of SARS-COV-2 Infection
Effect of Apollo Wearable on Long COVID-19 Symptoms.
The purpose of this study is to examine how Apollo wearable use impacts symptoms and quality of life following long COVID.
- Trial name
- NCT06097442
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Board of Medicine
Long COVID
Feasibility of Cannabidiol for the Treatment of Long COVID
This is an open label, phase 2 clinical trial to assess the feasibility of a cannabidiol (CBD) dominant medicinal cannabis for the treatment of Long COVID.
- Trial name
- NCT04997395
- Testing
- MediCabilis Cannabis sativa 50
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Bod Australia
Long Covid
Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER)
The purpose of this study is to better understand the biological changes associated with Long COVID and to identify laboratory tests (biomarkers) that may help diagnose the condition and measure how it changes over time.
- Trial name
- VIPER (NCT07770022)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco