Clinical trials: Post Dural Puncture Headache
Plasma Rich Fibrin, Epidural
Plasma Rich Fibrin Epidural Injection by Racz Catheter Versus Epidural Blood Patch in Postdural Puncture Headache
This study aims to evaluate plasma-rich fibrin epidural injection by Racz catheter and epidural blood patch in Post dural puncture headache.
- Conditions
- Plasma Rich Fibrin, Epidural, Racz Catheter, Epidural Blood Patch
- Trial name
- NCT06790745
- Testing
- Epidural blood patch, Plasma rich fibrin epidural injection by Racz catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Postdural Puncture Headache
Sphenopalatine Ganglion Block for Postdural Puncture Headache in the Emergency Department
This study evaluates sphenopalatine ganglion block (SPGB) for the treatment of postdural puncture headache (PDPH) in the emergency department (ED).
- Trial name
- NCT02517931
- Testing
- Sphenopalatine Ganglion Block
- Where
- United States
- Sponsor
- University of Arkansas
Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Predictive Value of ONSD and NIRS for PDPH
Currently, there is no reliable and effective method available in clinical practice to predict the development of PDPH. Early prediction and prevention of PDPH would reduce the incidence of postoperative complications, thereby…
- Trial name
- NCT07729449
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ordu University
Lumbar Puncture
Ultrasound-assisted vs Palpation-guided Lumbar Punctures
The goal of this randomized clinical trial is to determine whether ultrasound-assisted lumbar puncture improves first-needle insertion success compared with the standard palpation technique in adults undergoing a clinically…
- Trial name
- NCT07824284
- Testing
- Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- The Cooper Health System
PDPH
Prophylactic Intrathecal Normal Saline for Prevention of Post Dural Puncture Headache in Women Undergoing Cesarean Section Under Spinal Anesthesia
The rates of cesarean section are increasing worldwide despite ten to fifteen percent of World Health Organization recommendation and from which 80-90% of cesarean sections are performed with spinal anesthesia.
- Trial name
- PDPH (NCT04393766)
- Testing
- Normal Saline
- Where
- Ethiopia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Dilla University
Cesarean Section Complications
Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery
The Optic Nerve Sheath Diameter (ONSD), measured non-invasively by bedside ultrasound, is a well-established surrogate for intracranial pressure (ICP), as the optic nerve sheath is continuous with the intracranial dura mater and…
- Trial name
- NCT07360756
- Testing
- Study Cohort (Single Cohort)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Al-Azhar University
Post-Dural Puncture Headache
Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients
The purpose of this trial is to study the efficacy and efficiency of sphenopalatine ganglion block for management of post dural puncture headache in obstetric patients
- Trial name
- NCT04793490
- Testing
- Sphenopalatine ganglion block, paracetamol
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Post-Dural Puncture Headache
Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.
Post-dural puncture headache (PDPH) is a common and debilitating complication of spinal anesthesia in pregnant patients undergoing cesarean sections, with an incidence ranging from 0.5% to 2% (1).
- Trial name
- NCT06824025
- Testing
- lidocaine group ( nebulized lidocaine + saline) total volume 4 ml
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Minia University
Post Dural Puncture Headache
Caffeine Versus Placebo for Spinal Headaches
Caffeine will be studied against placebo in patients with positional headache after a lumbar puncture (aka "spinal headache").
- Trial name
- NCT00809627
- Testing
- Caffeine, saline
- Where
- United States
- Sponsor
- United States Naval Medical Center, Portsmouth
Pregnancy, Headache
The Effect of Patient Position on Postdural Puncture Headache
We aimed to investigate the association between the position in which spinal anesthesia was performed and postdural puncture headache occurrence.
- Trial name
- NCT02122419
- Testing
- lateral, sitting
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postdural Puncture Headache
Prediction of Post-dural Puncture Headache in Parturients Undergoing Elective Caesarean Section
The parturients are at particular risk of post dural puncture headache (PDPH) because of their sex, young age, and the widespread application of spinal and epidural anesthesia.
- Trial name
- NCT03464253
- Testing
- Performance of the transcranial Doppler (TCD)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Headache
Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache
Postdural puncture headache (PDPH) is a potential complication after spinal anesthesia caused by traction on pain-sensitive structures from low cerebrospinal fluid pressure (intracranial hypotension) following a leak of…
- Trial name
- NCT05108688
- Testing
- Mirtazapine, Sumatriptan
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Ain Shams University
Postdural Puncture Headache, Sphenopalatine Ganglion Block
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia.
- Trial name
- NCT02181205
- Testing
- bupivacaine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Post-lumbar Puncture Headache, Backache
What Needle Diameter Should Physician Use When They Perform Lumbar Puncture ? A Randomized Controlled Trial
This study is intended to help guide the choice of needle diameter when performing a lumbar puncture. Smaller spinal needles have been shown to decrease rate of adverse events such as post-lumbar puncture headache and hearing…
- Trial name
- NCT01481922
- Testing
- whitacre 24 gauge, whitacre 22 gauge
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- McGill University
Central Nervous System Infections, Pseudotumor Cerebri
A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control
This study will compare the VerTouch device to the conventional palpation technique for performing diagnostic and therapeutic neuraxial procedures.
- Conditions
- Central Nervous System Infections, Pseudotumor Cerebri, Neurological Disorder, Cancer
- Trial name
- NCT04796935
- Testing
- Tactile Imaging (VerTouch), Control (palpation)
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- IntuiTap Medical, Inc
Headache
Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache
We hypothesized that; intrathecal administration of neostgmine in spinal anesthesia may have a beneficial role in reduction of the incidence or severity of PDPH.
- Trial name
- NCT04905953
- Testing
- Neostigmine
- Where
- Egypt
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postdural Puncture Headache
Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache
The purpose of this study is to compare a pain block in the midface, versus the traditional, more invasive, therapeutic epidural patch for the treatment of headaches
- Trial name
- NCT03112720
- Testing
- Epidural Blood Patch, Sphenopalatine Ganglion Block
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Post-Dural Puncture Headache
Pathophysiological Mechanisms and Implication of Treatment in Postural Puncture Headache
To improve treatment for post dural puncture headache, its pathophysiology needs to be explored. Dural puncture alters CNS dynamics; using advanced MRI, we aim to investigate PDPHs pathophysiology explained by brain movement…
- Trial name
- PDPH (NCT06253754)
- Testing
- MRI examination
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Umeå University
Theophylline, Sumatriptan
Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache
The aim of this study is to compare the safety and efficacy of theophylline, sumatriptan, and gabapentin in the treatment of post-dural puncture headache.
- Conditions
- Theophylline, Sumatriptan, Gabapentin, Post-Dural Puncture Headache
- Trial name
- NCT07515456
- Testing
- Theophylline, Sumatriptan, Gabapentin
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University