Clinical trials: Post Dural Puncture Headache
Post-Dural Puncture Headache, Low Pressure Headache
Non-Luer Butterfly Needle With One-way Valve for the Epidural Blood Patch: Does it Alter Blood Clotting?
The Department of Health recommends using equipment which prevents wrong route drug administration. However, the epidural blood patch requires equipment that connects to the intravenous and epidural route.
- Trial name
- NCT03420352
- Testing
- Thromboelastography
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Post-Dural Puncture Headache
Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture
The purpose of this study is to evaluate Neostigmine and Glycopyrrolate to treat post-dural puncture headache (PDPH) to reduce the proportion of postpartum women with a PDPH requiring epidural blood patch (EBP) who developed a…
- Trial name
- NCT05116930
- Testing
- Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic
Post-Dural Puncture Headache
Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical Surgeries
Post-dural puncture headache (PDPH) or spinal (or post-spinal) headache is one of the most common side effects of spinal anesthesia, with an incidence of 6-36%.
- Trial name
- NCT06729047
- Testing
- normal Saline, Neostigmine, Ketorolac
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Assiut University
Post-Dural Puncture Headache, Cesarean Section Complications
Effects of MET on PPDH, Neck Pain and Disability After Cesarean Section
The goal of this clinical trial is to determine the effect of Muscle Energy Techniques on post dural puncture headache, neck pain and disability after Cesarean Section. .
- Trial name
- NCT05834140
- Testing
- Traditional Physical Therapy, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Postdural Puncture Headache
Examination of Postdural Puncture Headache Frequency, Predisposing Factors and Treatment
Post-dural puncture headache (PDPH) is one of the most important complications of neuraxial blocks and lumbar interventions for cerebrospinal fluid (CSF) examination.
- Trial name
- PDPH (NCT06394024)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mustafa Soner Ozcan
Postdural Puncture Headache
The Relationship Between Post Dural Puncture Headache and Joint Laxity
Post-spinal headache is divided into 3 according to the severity scale. It is divided into 3 groups as mild, moderate and severe according to the presence of symptoms such as nausea, vomiting, and dizziness that prevent daily…
- Trial name
- NCT05212194
- Testing
- examination
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University Research Hospital
Post-dural Puncture Headache
Aminophylline for Patients With Post-Dural Puncture Headache
Post-dural puncture headache (PDPH) is the most common complication of lumbar puncture. Its clinical manifestations are pain in the forehead and the occipital region, or diffuse headache.
- Trial name
- NCT02522013
- Testing
- Aminophylline, isotonic saline
- Where
- 4 sites in China
- Volunteers
- 126 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Headache
Treatment of Post-dural Puncture Headache in Postpartum Patients: Sphenopalatine Ganglion Block to Epidural Blood Patch.
The purpose of this research study is to compare the effectiveness of a sphenopalatine ganglion block to an epidural blood patch for post-dural puncture headache relief in randomized postpartum parturients over a 48 hour period.
- Trial name
- NCT02962427
- Testing
- Sphenopalatine ganglion Block, Epidural blood patch
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Colorado, Denver
Post Dural Puncture Headache
Comparison of Acetaminophen With Aminophylline and Aminophylline With Dexamethasone for Prophylaxis of PDPH in Patients With History of PDPH.
It is hypothesized that there is a difference between intravenously administered aminophylline with intravenous acetaminophen and intravenously administered aminophylline with dexamethasone for prevention of and reducing severity…
- Trial name
- PDPH (NCT07528118)
- Testing
- Inj Aminophylline 100mg with Inj Acetaminophen 1000mg in 100ml Normal Saline, Inj Aminophylline 100mg , with 0.1mg/kg Dexamethasone in 100ml Normal Saline
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Sargodha Medical College
Post-Dural Puncture Headache, Headache
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
This pilot randomised controlled trial compared sphenopalatine ganglion block (SPGB) using intranasal 2% lidocaine versus conservative management (bed rest and aggressive hydration) in patients who developed post-dural puncture…
- Trial name
- NCT07494383
- Testing
- Sphenopalatine ganglion block, Conservative management
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Pain, Headache
The Association Between Pain Catastrophizing Scale Score and Postspinal Headache
This study is aimed to elucidate the association between Pain Catastrophizing Scale Score and Postspinal Headache in Patients Underwent Cesarean Section With Spinal Anesthesia.
- Trial name
- NCT02727244
- Testing
- urgent or elective cesarean section
- Volunteers
- 300 people
- Sponsor
- Tokat Gaziosmanpasa University
Post-Dural Puncture Headache
Two Fluid Strategies for Prevention of Post-dural Puncture Headache
Postdural puncture headache (PDPH) is a common complication after cesarean delivery (CD). The role of peri-operative fluid therapy in prophylaxis against PDPH is unclear.
- Trial name
- NCT03475784
- Testing
- Restrictive fluid therapy, Liberal fluid therapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Anesthesia
Postdural Puncture Headache Relief With Aminophylline and SPGB
The purpose of the study is to compare Sphenopalatine ganglion block (SPGB) and aminophylline in the efficacy and safety management of PDPH.
- Trial name
- NCT05552404
- Testing
- conservative therapy, Aminophylline, trans nasal sphenopalatine ganglion block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post Dural Puncture Headache
Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients
Some patients develop headache after spinal anesthesia used during cesarean section. This condition is called post-dural puncture headache (PDPH). Early identification of patients at risk may improve patient care.
- Trial name
- NCT07497945
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Kocaeli University
Post-Dural Puncture Headache
Evaluation of Post-dural Puncture Headache in Female Patients Undergoing Obstetric and Non-obstetric Surgery
The goal of this observational study is to compare the incidence, severity, and potential risk factors for Post-dural Puncture headaches (PDPH) in obstetric and non-obstetric female patients undergoing spinal anesthesia.
- Trial name
- NCT06992063
- Testing
- Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Duzce University
Post-Dural Puncture Headache
Trans-nasal Sphenopalatine Ganglion Block Versus Ultrasound-guided Bilateral Greater and Lesser Occipital Nerve Block for Management of Post-Dural Puncture Headache.
Post-Dural Puncture Headache (PDPH) is a complication associated with spinal anesthesia. While conventional treatments are available, the Epidural Blood Patch (EBP) is considered the gold standard.
- Trial name
- TNSPGB /GALONB (NCT06705244)
- Testing
- Trans-nasal sphenopalatine nerve block, Greater and lesser occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Analgesia
Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin
The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects…
- Trial name
- NCT04662125
- Testing
- caffeine, paracetamol tablet, Oral prednisolone, oral pregabalin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postdural Puncture Headache
Sphenopalatine Ganglion Block for Postdural Puncture Headache
Background: Postdural puncture headache (PDPH), which is one of the complications of spinal anesthesia, is a condition that negatively affects the quality of life of patients, causes late mobilization and prolonged hospital stay.
- Trial name
- NCT04892290
- Testing
- Conservative Treatment for Postdural Puncture Headache
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sakarya University
Obstetric Anesthesia Problems, Headache
Post-dural Puncture Headache: A Retrospective Study
Neuraxial techniques are widely used in obstetric practice to provide analgesia and anesthesia. A common complication associated with neuraxial anesthesia is post-dural puncture headache (PDPH), resulting from unintentional or…
- Conditions
- Obstetric Anesthesia Problems, Headache, Epidural; Anesthesia, Headache
- Trial name
- NCT03790124
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Augusta University
Post-Dural Puncture Headache
Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.
This study will be conducted to better comprehend the effect of aminophylline in comparison to magnesium sulphate on preventing and/or treating PDPH.
- Trial name
- NCT06272916
- Volunteers
- 630 people
- Sponsor
- Assiut University