Clinical trials: Post ERCP Pancreatitis
Post-ERCP Acute Pancreatitis
IV Ibuprofen for the Prevention of Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is an advanced endoscopic technique utilized to diagnose and treat pathologic conditions involving the ducts draining the liver and pancreas.
- Trial name
- NCT02241512
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Texas Southwestern Medical Center
Post-ERCP Acute Pancreatitis
7 cm vs. 5 cm Pancreatic Stents for the Prevention of Post-ERCP Pancreatitis in High-risk Patients
Acute pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). The incidence of post-ERCP pancreatitis (PEP) is estimated to be 10% to 15% in high-risk patients.
- Trial name
- NCT04145336
- Testing
- 5cm 5-Fr PDS, 7cm 5-Fr PDS, Indomethacin
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Air Force Military Medical University, China
Post-ERCP Acute Pancreatitis
Oral Losartan in Prevention of Post-ERCP Paancreatitis
Oral losartan given in the dose of 50 mg one hour before ERCP was studied in the prevention of post ERCP pancreatitis in 50 patients indicated for ERCP in comparison with another 50 patients underwent ERCP without receiving oral…
- Trial name
- NCT04049734
- Testing
- oral losatan
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Post-ERCP Pancreatitis
Rectal Indomethacin in the Prevention of Post-ERCP Pancreatitis
It is now established that indomethacin, a non-steroidal anti-inflammatory drug, at a dose of 100 mg, is effective in reducing the frequency and severity of pancreatitis (inflammation of the pancreas) after endoscopic retrograde…
- Trial name
- NCT01912716
- Testing
- high dose indomethacin, standard dose indomethacin
- Where
- 6 sites in United States
- Volunteers
- 1,037 people
- Sponsor
- Indiana University
Post-ERCP Acute Pancreatitis, Cholangitis
ERCP in Super-aged Patients Considering Difficult Cannulation: Challenges and Adverse Events
Today 11 percent of China's population is over the age of 65, and according to United Nations, it will take China just 20 years for the proportion of the elderly population to double to 25%.
- Trial name
- NCT03771547
- Testing
- ERCP
- Where
- China
- Volunteers
- 614 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Post-ERCP Acute Pancreatitis, Epinephrine
Effect of Papillary Epinephrine Spraying for the Prevention of Post-ERCP Pancreatitis in Patients Received Octreotide
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common complication with high costs, significant morbidity and even mortality.
- Trial name
- NCT03756116
- Testing
- Epinephrine sprayed on the papilla, Saline sprayed on the papilla
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Post-ERCP Pancreatitis
Pharmacological Prophylaxis of Post- Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The investigators aimed to perform a comparative study, evaluating the efficacy of three prophylactic approaches aiming to reduce the risk of post-ERCP pancreatitis, using pharmacologic agents with different mechanisms of action…
- Trial name
- NCT03708458
- Testing
- indomethacin suppository, N-acetylcysteine (NAC)
- Where
- Romania
- Volunteers
- 250 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Post-ERCP Acute Pancreatitis
Trial of Aggressive Hydration Versus Rectal Indomethacin for Prevention of Post-ERCP Pancreatitis
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a commonly performed endoscopic procedure used to treat pancreato-biliary pathology.
- Trial name
- AHRI-PEP (NCT03629600)
- Testing
- Lactated Ringer, Rectal Form Indometacin
- Where
- India
- Volunteers
- 352 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Post-ERCP Acute Pancreatitis
Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis is a well-known and sometimes life-threatening complication of ERCP. Both LR and rectal indomethacin have shown benefit in preventing post-ERCP pancreatitis.
- Trial name
- IND+LRPEP (NCT02641561)
- Testing
- Indomethacin, Lactated Ringer's Solution, Normal Saline
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Post-ERCP Acute Pancreatitis
Randomized Trial of Rectal Indomethacin and Papillary Spray of Epinephrine Versus Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
This research is being done to see if using a combination of rectal indomethacin and epinephrine spray during endoscopy, can prevent pancreatitis that may occur after ERCP (a type of gastrointestinal endoscopy).
- Trial name
- INDIEH (NCT02116309)
- Testing
- Rectal Indomethacin, Epinephrine
- Where
- 4 sites in United States, India
- Volunteers
- 948 people
- Sponsor
- Johns Hopkins University
Post-ERCP Acute Pancreatitis
Post-ERCP Pancreatitis Prevention by Stent Insertion
The presented study is designed to analyze the efficacy of pancreatic stent insertion in patients undergoing ERCP with accidental cannulation of the pancreatic duct.
- Trial name
- PEPSI (NCT01673763)
- Testing
- Stent insertion into the main pancreatic duct
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 169 people
- Sponsor
- Technical University of Munich
Post-ERCP Acute Pancreatitis
Lactated Ringer's Solution to Prevent Post-ERCP Pancreatitis
This is a randomized, double-blinded, controlled trial. This study is a head to head comparison of normal saline (NS) infusion versus Lactated Ringer's (LR) infusion in patients, with the primary outcome of post-ERCP pancreatitis…
- Trial name
- NCT03215862
- Testing
- Lactated Ringer, Normal Saline 0.9% Infusion Solution Bag
- Volunteers
- 242 people
- Sponsor
- University of South Florida
Post-ERCP Acute Pancreatitis, Pancreatic Duct Stricture
Short Term Pancreatic Stenting Registry
The purpose of this study is to document clinical utility and distribution of indications for short term pancreatic stenting, and stent type preference by indication at tertiary referral centers with expertise in pancreatic…
- Conditions
- Post-ERCP Acute Pancreatitis, Pancreatic Duct Stricture, Pancreatic Duct Stones, Pancreatic Duct Leakage
- Trial name
- NCT02262845
- Testing
- The Advanix™ Pancreatic Stent and NaviFlex RX Pancreatic Delivery System and Pushers
- Where
- 7 sites in United States, Germany and 2 more
- Volunteers
- 246 people
- Sponsor
- Boston Scientific Corporation
Post-ERCP Acute Pancreatitis
ENBD After Endoscopic Sphincterotomy Plus Large-balloon Dilation for Preventing PEP
Endoscopic retrograde cholangiopancreatography (ERCP) has become one of the most important techniques in the treatment of bile duct stones.
- Trial name
- NCT02830984
- Testing
- EST+LBD+ENBD, EST+LBD
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Anhui Provincial Hospital
Post-ERCP Acute Pancreatitis
Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) has been a well-recognized complication with significant morbidity and even mortality.
- Trial name
- NCT02839356
- Testing
- epinephrine, normal saline
- Where
- China
- Volunteers
- 670 people
- Sponsor
- Anhui Provincial Hospital
Post-ERCP Acute Pancreatitis
Incidence and Risk Factor of Post-ERCP Pancreatitis in Chronic Pancreatitis
The purpose of this study is to compare the incidence of post-ERCP pancreatitis (PEP) in chronic pancreatitis (CP) patients to that in biliary disease patients, to determine whether CP patients in early clinical stage have a…
- Trial name
- NCT02781987
- Testing
- chronic pancreatitis
- Volunteers
- 2,028 people
- Sponsor
- Changhai Hospital
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The purpose of this study is to assess whether peri-procedural administration of rectal indomethacin, compared to placebo, can reduce the incidence of post-ERCP pancreatitis.
- Trial name
- NCT01774604
- Testing
- Indomethacin
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Post-ERCP Acute Pancreatitis
A Prospective Trial of Aggressive Hydration Strategy to Reduce Post-ERCP Pancreatitis
Postendoscopic retrograde cholangiopancreatography pancreatitis is the most frequent and serious complication of ERCP procedures, occurring in approximately 5-15% of unselected patients.
- Trial name
- NCT02308891
- Testing
- lactated Ringer's solution (vigorous hydration arm), lactated Ringer's solution (standard hydration arm), endoscopic retrograde cholangiopancreatography (ERCP)
- Where
- 3 sites in South Korea
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Dankook University
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Acute pancreatitis is the most common and feared complication of ERCP, occurring after 1% to 30% of procedures. Since 2012, a multicenter RCT was published in NEJM, indomethacin use in high risk patients was considered a…
- Trial name
- Indomethacin (NCT02002650)
- Testing
- Pre-ERCP rectal Indomethacin, Post-operational Rectal Indomethacin
- Where
- 6 sites in China
- Volunteers
- 2,600 people
- Sponsor
- Air Force Military Medical University, China
Post ERCP Acute Pancreatitis
Indomethacin Decreases Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is now a widely accepted therapy for treating benign and malignant diseases of the pancreatobiliary tree.
- Trial name
- Indomethacin (NCT02110810)
- Testing
- Indomethacin, 2.6-g suppository of glycerin
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Instituto Mexicano del Seguro Social