Clinical trials: Post Extraction Complication
Pain, Post-Operative Pain
Ibuprofen Extended-Release Dental Pain Study
The purpose of this study is to evaluate the efficacy and safety of multiple doses of Ibuprofen 600 mg Extended-Release Tablets in a study of dental pain following extraction of third molar teeth.
- Conditions
- Pain, Post-Operative Pain, Third Molar Extraction
- Trial name
- NCT00707057
- Testing
- Ibuprofen 600 mg Extended-Release Tablets
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- SCOLR Pharma, Inc.
Acute Pain
Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
This study aims to evaluate the analgesic efficacy of single and multiple doses of a new fixed dose combination of nefopam hydrochloride 30 mg and paracetamol 500mg taken orally in comparison to each single component.
- Trial name
- NCT04622735
- Testing
- nefopam hydrochloride 30mg / paracetamol 500mg X2, Paracetamol 500 Mg Oral Tablet X2, Nefopam HCl 30 MG Oral Tablet X2
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 321 people
- Sponsor
- Unither Pharmaceuticals, France
Acute Pain, Postoperative
This is a Study Evaluating the Efficacy and Safety of LTG-001 for Acute Pain After Surgical Removal of Impacted Third Molars
The goal of this clinical trial is to learn if LTG-001 works to treat pain after third molar removal surgery in adults. It will also learn about the safety of LTG-001.
- Trial name
- NCT06774625
- Testing
- LTG-001 High Dose, LTG-001 Mid Dose, LTG-001 Low Dose
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Latigo Biotherapeutics
Postoperative Complications, Cataract
Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery
The primary objective of this study was to investigate the efficacy of bromfenac sodium ophthalmic solution 0.09% for treatment of post-operative ocular inflammation in subjects who undergo cataract extraction and intraocular…
- Trial name
- NCT00198445
- Testing
- Bromfenac
- Where
- 39 sites in United States
- Volunteers
- 527 people
- Sponsor
- Bausch & Lomb Incorporated
Post-Operative Pain, Third Molar Extraction
Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction
This study involves approximately 200 patients designed to evaluate the efficacy and safety of intranasal (IN) morphine 7.5 mg and 15 mg, intravenous morphine (IV) 7.5 mg, immediate release oral (PO) morphine 60 mg or placebo in…
- Trial name
- NCT00390312
- Testing
- Intranasal Morphine 15 mg, Immediate Release Oral Morphine 60 mg, Intravenous morphine
- Volunteers
- 225 people
- Sponsor
- Javelin Pharmaceuticals
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Kidney Calculi
Stone Access and Removal (STAR) Study
The purpose of the study is to assess procedural completion, the post-operative stone clearance and the safety profile following robotic mini-Percutaneous Nephrolithotomy (PCNL) performed with the MONARCH Platform, Urology.
- Trial name
- STAR (NCT06330701)
- Testing
- Robotic-assisted mini-PCNL
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Auris Health, Inc.
Acute Pain, Postoperative Pain
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
The goal of the present phase IIb clinical trial was to compare the safety and efficacy of the fixed-dose combination etoricoxib-tramadol 120mg/100mg tablet (once a day, for three days) versus naproxen 220mg tablet plus tramadol…
- Trial name
- NCT05995912
- Testing
- etoricoxib-tramadol, Naproxen, Tramadol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Laboratorios Liomont
Postoperative Pain
Efficacy and Safety of ALGRX 4975 in the Treatment of Postoperative Pain After Gall Bladder Removal
Postoperative pain after gall bladder removal can be significant, mobility limiting and extend hospital stay. ALGRX 4975 is an ultra-pure form of capsaicin, which is a pain medicine that has the potential for long-term pain…
- Trial name
- NCT00133133
- Testing
- ALGRX 4975
- Where
- Serbia and Montenegro
- Volunteers
- 40 people
- Sponsor
- AlgoRx Pharmaceuticals
Acute Post Operative Pain, Third Molar Extraction Surgery
A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction
The study will test the investigational product gel against placebo (which contains no active ingredient) to determine if it is safe after wisdom tooth extraction. The main questions the study will answer are: 1.
- Trial name
- NCT06864884
- Testing
- ARC-001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Arcato Laboratories, Inc.
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Pain, Postoperative Pain
A Comparative Study of JNS013 in Participants With Post-Tooth-Extraction Pain
The purpose of this study is to evaluate the efficacy and safety of JNS013 with single oral dose administration in participants with pain after tooth-extraction of mandibular impacted wisdom tooth.
- Trial name
- NCT00737048
- Testing
- Tramadol Hydrochloride, Acetaminophen, Tramadol plus Acetaminophen
- Where
- 11 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Janssen Pharmaceutical K.K.
Pain
Dental Pain 3rd Molar Tooth Extraction GW842166
This phase IIa (proof of concept) study will be conducted as a multi-centre study within the European Union (EU). It will be conducted to a randomised, single blind, placebo- controlled, parallel group design with a positive…
- Trial name
- NCT00444769
- Testing
- GW842166
- Where
- 3 sites in Germany, Italy and 1 more
- Volunteers
- 112 people
- Sponsor
- GlaxoSmithKline
Acute Postoperative Pain, Dental Pain
A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
The primary objective of this trial is to assess the safety and tolerability of single, ascending doses of CYT-1010 in healthy male and female volunteers and in the treatment of acute postoperative pain after third molar…
- Trial name
- NCT07905105
- Testing
- CYT-1010
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cytogel Pharma, LLC
Surgery--Complications, Molar, Third
Probiotic Intervention After Surgical Removal of Mandibular Third Molars
Single-center, double-blind, randomized trial of probiotics L. plantarum KABP-051 (CECT7481) and L. brevis KABP-052 (CECT7480) taken twice daily for 7 days after surgical removal of both mandibular 3rd molars.
- Trial name
- NCT04203771
- Testing
- Probiotic AB-DENTALAC, Surgical removal of mandibular third molars at baseline, Ibuprofen
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Acute Pain
Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar
The study is aimed to evaluate the analgesic efficacy of TRAM.HCl/DKP.TRIS 75mg/25mg oral fixed drug combination in comparison with TRAM.HCl /paracetamol 75mg/650mg in the treatment of moderate to severe acute pain.
- Trial name
- DAVID (NCT02777970)
- Testing
- Tramadol Hydrochloride/Dexketoprofen Trometamol, Tramadol Hydrochloride/Paracetamol
- Where
- 18 sites in Hungary, Italy and 3 more
- Volunteers
- 654 people
- Sponsor
- Menarini Group