Clinical trials: Post Mastectomy Pain Syndrome
Post-mastectomy Pain Syndrome, Myofascial Pain Syndrome
Trigger Point Injections for Post-Mastectomy Pain Syndrome
Post-Mastectomy Pain Syndrome (PMPS) is a chronic pain that persists for more than three months after a surgical breast procedure. It has 11-70% incidence in patients that underwent a breast surgery.
- Conditions
- Post-mastectomy Pain Syndrome, Myofascial Pain Syndrome, Trigger Point Pain, Myofascial, Breast Cancer
- Trial name
- NCT04267315
- Testing
- Trigger point injection, Subcutaneous saline injection, Comprehensive Rehabilitation program
- Where
- 2 sites in Brazil
- Volunteers
- 72 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Axillary Web Syndrome, Post-mastectomy
Effects of Muscle Energy Techniques With and Without Manual Axial Distraction in Post-Mastectomy Patients With Axillary Web Syndrome
This randomized controlled trial aims to evaluate the effects of muscle energy techniques with and without manual axial distraction among post-mastectomy patients with axillary web syndrome.
- Trial name
- MET MAD PM AWS (NCT07266623)
- Testing
- Muscle energy technique + Manual axial distraction, Muscle energy technique
- Volunteers
- 58 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Chronic Pain
Does Pecs II Block Reduce the Incidence of Post Mastectomy Pain Syndrome (PMPS)? A Cross Sectional Study
Post mastectomy pain syndrome (PMPS) is a chronic pain condition that develops after breast cancer surgery. The objective of this study was to determine if Pecs II block administered prior to general anesthesia (GA) reduced the…
- Trial name
- PMPS (NCT04095897)
- Testing
- Pecs II Block
- Where
- Malaysia
- Volunteers
- 288 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Chronic Postoperative Pain
Preoperative Erector Spinae Plane Block Versus Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome
Breast cancer is considered the commonest malignancy affecting women with an incidence exceeding one million cases per year. Although it has a favorable prognosis with improved lines of treatment, some complications may still…
- Trial name
- NCT06036979
- Testing
- Paravertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Chronic Pain, Pain Measurement
Relationship of Intra-Epidermal Nerve Fibre Density (IENFD) and Structure to Chronic Post-Mastectomy Pain Syndrome (PMPS)
This is a retrospective, observational study which will utilise the Edinburgh Cancer Research Centre's Tissue Bank to provide samples for IENFD testing in those who have undergone mastectomy surgery for breast cancer.
- Conditions
- Chronic Pain, Pain Measurement, Mastectomy, Postoperative Pain
- Trial name
- NCT02919891
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Post Mastectomy Pain Syndrome
Comparison Between Pregabalin and Acetaminophen for the Treatment of Post-Mastectomy Pain Syndrome
The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing…
- Trial name
- NCT07567924
- Testing
- Pregabalin, Acetaminophen
- Where
- Pakistan
- Volunteers
- 158 people
- Sponsor
- Subas Ali
Breast Neoplasms, Pain, Postoperative
Persistant Post-mastectomy Pain in Breast Cancer : Incidence and Risk Factors
Post Mastectomy Pain Syndrome (PMPS) is a major complication of breast surgery responsible for depression and disability. The project consists of a prospective cohort on patients going for oncological breast surgery at National…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04676438
- Where
- 2 sites in Morocco
- Volunteers
- 722 people
- Sponsor
- Moroccan Society of Surgery
Breast Neoplasms, Pain, Postoperative
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic, Post-Mastectomy Chronic Pain Syndrome
- Trial name
- USB22 (NCT05494281)
- Testing
- Serratus Anterior Plane Block with local anesthetic, Serratus Anterior Plane Block with saline solution
- Where
- Morocco
- Volunteers
- 94 people
- Sponsor
- Moroccan Society of Surgery
Stellate Ganglion, Radiofrequency Ablation
Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syndrome
The aim of this study is to evaluate the efficacy of the combination of Ultra Sound (US) guided radiofrequency stellate ganglion block (SGB) and radiofrequency Thoracic Paravertebral block (TPVB) comparing to US-guided SGB or…
- Conditions
- Stellate Ganglion, Radiofrequency Ablation, Complex Regional Pain Syndromes, Mastectomy
- Trial name
- NCT06033456
- Testing
- Radiofrequency stellate ganglion block using ultrasound guidance (SGB), Radiofrequency thoracic (T2, T3) paravertebral block under fluoroscopic guidance (TPVB), Combined radiofrequency of stellate ganglion block plus thoracic T2, T3 paravertebral block
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- National Cancer Institute, Egypt
Post-Mastectomy Chronic Pain Syndrome
Dex & Mastectomy Pain
Chronic post-surgical pain is a common complication following mastectomy and represents a significant source of long-term morbidity.
- Trial name
- NCT07556952
- Testing
- Dexamethasone (intravenous), Normal Saline (0.9% NaCl)
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Dexamethasone, Glucocorticoids
High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy
The aim of this study is to investigate the effect of a single preoperative high-dose steroid injection on complications in the immediate postoperative phase after breast cancer surgery, with removal of the breast (mastectomy).
- Conditions
- Dexamethasone, Glucocorticoids, Mastectomy, Breast Cancer
- Trial name
- DEX-MAS (NCT03125941)
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Amantadine, Duloxetine
Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
- Conditions
- Amantadine, Duloxetine, Pregabalin, Mastectomy
- Trial name
- NCT07421427
- Testing
- Pregabalin, Pregabalin + Amantadine, Pregabalin + Duloxetine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Post-Mastectomy Neuropathic Pain Syndrome
Serratus Plane Block (SPB) Versus Capsaïcine Versus Botox-A for Chronic Neuropathic Pain in Post-mastectomy Syndrome
The goal of this phase II clinical trial is to study the effectiveness of a treatment with Serratus Plane Block (SPB) or Botox-A in comparison with capsaicin for the control of chronic neuropathic pain of post-mastectomy syndrom…
- Trial name
- SERCABOT (NCT06807164)
- Testing
- Capsaicin 8% Patch, Serratus Plane Block, Botulinum Toxin A
- Where
- France
- Sponsor
- Centre Oscar Lambret
Chronic Pain
Physical Exercise, Motor Activity and Depression in Post-mastectomy Pain Syndrome
Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli.
- Trial name
- NCT06123559
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Post-mastectomy Pain Syndrome
Stellate Ganglion Destruction With Alcohol Versus Thermal Ablation for Chronic Post Mastectomy Pain
Group A: SGB with alcohol injection by ultrasound guidance and C7 level confirmation by fluoroscopy. Group B: Thermal RF; thermal RF neurolysis will be applied with a time of 60 seconds at 80º C, and then will be repeated twice .
- Trial name
- NCT05771103
- Testing
- thermal Radiofrequency neurolysis of Stellate ganglion
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Pulsed Radiofrequency, Shoulder Individual Nerves Brachial Plexus
Pulsed Radiofrequency of Shoulder Individual Nerves Versus Brachial Plexus in Management of Chronic Post Mastectomy Shoulder Pain
this study aims to assess the role of pulsed radiofrequency of the brachial plexus or pulsed radiofrequency of shoulder individual nerves in the management of post-mastectomy shoulder pain.
- Conditions
- Pulsed Radiofrequency, Shoulder Individual Nerves Brachial Plexus, Chronic, Post Mastectomy
- Trial name
- NCT07002944
- Testing
- Brachial plexus pulsed radiofrequency, Sholder individual nerves pulsed radiofrequency, Control
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Post-mastectomy Pain Syndrome
Comparison of Kinesiotaping and Graded Exposure Therapy on Kinesiophobia in Post-Mastectomy Patients
The aim of this research is to compare the effect of Comparison of Kinesiotaping and Graded exposure therapy on Kinesiophobia in Post-Mastectomy patients. The sample size was 30.
- Trial name
- NCT06658314
- Testing
- Experimental interventional group 1(Kinesiotaping), Experimental interventional group II (Graded exposure therapy)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Post-mastectomy Pain Syndrome
Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome
Chronic postoperative pain is an entity that is usually neglected by anesthetists, but several studies show that the choice of anesthetic technique may interfere with this prevalence.
- Trial name
- NCT03965442
- Testing
- Control, Esmolol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Hospital de Base
Pain Syndrome, Mastectomy
Postmastectomy Pain Syndrome in an Indian Cancer Hospital
Breast cancer is the most common cancer in women in India and accounts for 27% of all cancers in women. Incidence rises in early thirties, peaks at 50-64 years. Approximately 48% are below 50 years of age.
- Conditions
- Pain Syndrome, Mastectomy, Quality of Life
- Trial name
- NCT03067922
- Testing
- Non interventional study
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Tata Memorial Centre
Post-Mastectomy Chronic Pain Syndrome
Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Post-mastectomy pain due to nerve injury leads to long-term opioid use and diminished quality-of-life. The investigators on this study will evaluate the regenerative peripheral nerve interface (RPNI), a novel surgical approach to…
- Trial name
- RPNI (NCT04530526)
- Testing
- Regenerative Peripheral Nerve Interface
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan Rogel Cancer Center