Clinical trials: Post Menopausal, open to volunteers
Post-menopause, Pre-menopause
VEDA Study (DHEA vs Estradiol)
This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause.
- Conditions
- Post-menopause, Pre-menopause, Sexual Function, Menopause
- Trial name
- NCT07574216
- Testing
- DHEA ovals, Estradiol 0.01% Vag Cream
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Post Menopausal Osteoporosis
Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis
Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality.
- Trial name
- NUTRANACRE (NCT05571514)
- Testing
- Mother-of-pearl, Calcium Carbonate
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Menopause Related Conditions, Exercise Training
Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLE (NCT07617454)
- Testing
- Estrogel, Physical exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Coronary Artery Disease (CAD), Menopause
Serum Endogenous Estrogens, Estrogen Receptors, and Sirtuin-1 and -3 After Resveratrol Supplementation
Atherosclerotic coronary artery disease (CAD) is a leading cause of mortality among postmenopausal women. Resveratrol, a phenolic compound with antioxidant properties, may influence lipid metabolism, endothelial function, and…
- Conditions
- Coronary Artery Disease (CAD), Menopause, Hormones
- Trial name
- RESEARCH (NCT07865377)
- Testing
- Trans-resveratrol, 1000 mg daily for 90 days
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- InCor Heart Institute
Obesity, Menopause Hot Flashes
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
The purpose of this study is to determine the effect of tirzepatide on vasomotor symptoms and on measures of biological aging.
- Trial name
- NCT07218445
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoporosis in Post-menopausal Women
A Clinical Study on the Effect of Discontinuing Alendronate in Postmenopausal Women With Osteoporosis After a Treatment Period Without Fractures
The goal of this clinical trial is to study the effects of discontinuation of Alendronate treatment for three years. The participants are postmenopausal women with osteoporosis, who have had a treatment period without fractures.
- Trial name
- ALEXIS (NCT06864130)
- Testing
- Alendronate 70mg weekly
- Where
- 7 sites in Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Hypertension, Oedema
A Clinical Study Comparing Ankle Swelling Caused by Two Different Blood Pressure Medications, Levamlodipine and Amlodipine, in Post-menopausal Women With Mild High Blood Pressure.
High blood pressure is often treated with a medication called Amlodipine, but it can cause uncomfortable ankle swelling, especially in women.
- Trial name
- TERESA (NCT07618806)
- Testing
- Amlodipine
- Volunteers
- 344 people
- Sponsor
- Zentiva, k.s.
Post Menopausal, Osteoporosis
EFFECT OF CIRCUIT TRAINING ON BONE MINERAL DENSITY IN POST MENOPAUSAL PERIOD
This study will be conducted to determine the effect of circuit training on bone mineral density in post menopausal period.
- Trial name
- CWT and BMD (NCT06950463)
- Testing
- Group A (control group): It will be consisted of twenty two post menopausal women who will receive daily dosage of vitamin D3 supplement (600 IU/day) (Schleicher et al., 2016), for 6 week, 1-Dumbbells (set B08Z7SY6SP ,Gymbit , made in China) :They will be used for the treatment procedures of circuit training for all postmenopausal women in group B. Its surface is coated with vinyl fo
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hormone, Cardiovascular
Cardiometabolic and Hormonal Adaptations to 4-Month Zumba Training in Overweight/Obese Women
This study aims to evaluate the effects of a 4 month Zumba training program on cardiometabolic, hormonal, inflammatory, hepatic, renal, and functional parameters in overweight and obese women.
- Conditions
- Hormone, Cardiovascular, Obesity & Overweight
- Trial name
- NCT07264348
- Testing
- Zumba training
- Volunteers
- 73 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Hormone Receptor Positive Early Breast Cancer
A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer
The study aims to compare the amount of the drug letrozole that gets into the bloodstream after multiple doses of the quarterly injection Letrozole SIE, versus multiple doses of the standard oral daily tablet of letrozole…
- Trial name
- SIE-1 (NCT07401381)
- Testing
- US-sourced oral Femara® + Letrozole SIE, EU sourced oral Femara® + Letrozole SIE
- Where
- 21 sites in United States, Serbia and 1 more
- Volunteers
- 120 people
- Sponsor
- Rovi Pharmaceuticals Laboratories
Neck Pain
Effect of Sensory Motor Training for Neck Muscles on Hand Grip Strength in Post-menopausal Fibromyalgia Neck Pain.
This study will be conducted to investigate the effect of sensory motor training for neck muscles on hand grip strength in post-menopausal fibromyalgia neck pain.
- Trial name
- NCT07624188
- Testing
- Neuro dynamic nerve gliding exercises, Sensory motor neck training
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Gynecological Oncology, Gynecology
Yoga in Women With Surgical Menopause After Gynecological Cancer
This randomized controlled trial investigates the effects of yoga on quality of life, sleep quality, and spiritual well-being in women who have entered surgical menopause after gynecological cancer surgery.
- Conditions
- Gynecological Oncology, Gynecology, Oncology, Surgical Menopause
- Trial name
- NCT07141953
- Testing
- Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Dokuz Eylul University
Post-menopause
Beetroot Juice: a Natural Aid for Boosting the Health Benefits of Exercise in Post-menopausal Women?
Menopause and ageing bring several changes to women's health, partly due to a decline in the hormone estrogen. This reduction affects multiple systems in the body, including muscles and bones, and also influences the production…
- Trial name
- BEETBOOST (NCT07572877)
- Testing
- Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Western Norway University of Applied Sciences
Cardiovascular Kidney Metabolic Syndrome, Type 2 Diabetes
Food and Fitness With Medicine (FFWM)
Food and Fitness with Medicine (FFWM) is a 24-week randomized controlled trial (RCT) enrolling 200 post-menopausal women (PMW) with stage 2 cardio-kidney metabolic (CKM) syndrome and type-2 diabetes (T2D) within 6 weeks of…
- Trial name
- FFWM (NCT07027995)
- Testing
- Exercise is Medicine (EIM), Culinary Education, Food is Medicine
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Ohio State University
Muscle Mass and Strength, Menopause
Significance of Estrogen Status for Muscle Function, Physical Fitness, and Physiological Health Parameters - a Comparison of Age-matched Groups of Women Before and After Menopause.
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLEX (NCT07649356)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Osteoporosis in Post-menopausal Women
Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMD
Osteoporosis is associated with a high risk of fractures, disability, loss of independence, and excess mortality. Zoledronic acid is an established first-line treatment in Sweden, but many patients at high fracture risk remain at…
- Trial name
- STRONG-HIP (NCT07772609)
- Testing
- Romosozumab, Zoledronic Acid 5 MG in 5 ML Injection, Calcium 500 mg and Vitamin D3 800 IU
- Where
- 9 sites in Sweden
- Volunteers
- 216 people
- Sponsor
- Sahlgrenska University Hospital
Menopause
Brazilian Registry of Menopausal Health
The Brazilian Registry of Menopausal Health is a national study aimed to better understand the health and quality of life of participants aged 35 to 65 who are in the menopausal transition or postmenopausal phase, including…
- Trial name
- EMBRACE (NCT07005648)
- Where
- Brazil
- Volunteers
- 1,592 people, healthy volunteers welcome
- Sponsor
- Science Valley Research Institute
Menopause
Menopausal Symptoms Probiotic Study
In this study, we want to investigate if the active product consisting of a probiotic blend can potentiate the recirculation of active oestrogens into the bloodstream and help to mitigate menopause symptoms, which are closely…
- Trial name
- NCT06446869
- Testing
- Gyntima Menopause
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Community Pharmacology Services Ltd
Breast Cancer
Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer.
The purpose of the study is to to compare low dose of exemestane (babyexe) versus low dose of tamoxifen (babytam) in terms of change of quality of life from baseline to 12 months.
- Trial name
- BabyTears (NCT06364267)
- Testing
- Tamoxifen 10 MG, Exemestane 25 MG
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Andrea DeCensi