Clinical trials: Post Myocardial Infarction
Myocardial Infarction
Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone With the NOGA System
Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters.
- Trial name
- SCARPACE (NCT04757168)
- Testing
- NOGA TM probe
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Acute Myocardial Infarction
A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction
The objective is to obtain initial information regarding the safety and efficacy of the use of Filgrastim in the setting of acute myocardial infarction.
- Trial name
- NCT00215124
- Testing
- Filgrastim
- Where
- United States
- Sponsor
- The Cleveland Clinic
Myocardial Infarction
THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction
The occurrence of no-reflow phenomenon after recanalization of the infarct related artery in acute myocardial infarction is described in up to 40% of cases.
- Trial name
- REOPEN-AMI (NCT00590070)
- Testing
- adenosine, nitroprusside
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Myocardial Infarction: Rehabilitation Phase
Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute MI
Ischemic heart disease remains the leading cause of death in the western world. The beneficial effects of cardiac rehabilitation on the evolution of ischemic heart disease are known, but the effects of rehabilitation on the…
- Trial name
- RIABILITOMICA (NCT06298513)
- Testing
- Cardiac rehabilitation
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Istituto Auxologico Italiano
Myocardial Infarction, Periodontal Diseases
Non-invasive Assessment of Inflammatory Markers MIP-1 Alpha and IL-6 in Saliva of Post Myocardial Infarction and Stage 4 Periodontitis Patients
Periodontitis is an immunoinflammatory disease caused by microorganisms leading to sequential loss of the supporting structures of periodontium, resulting in periodontal pocket formation, gingival recession eventually leading to…
- Trial name
- NCT05314192
- Testing
- salivary test
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ajman University
Myocardial Infarction
Trimethylamine N-oxide in Myocardial Infarction
Trimethylamine-N-oxide (TMAO) is produced from the metabolism of gut microbiota and is reportedly pro-atherogenic and associated with cardiovascular events.
- Trial name
- NCT03418285
- Volunteers
- 112 people
- Sponsor
- Yokohama City University Medical Center
Myocardial Infarction
Routine Angioplasty and Stenting After Fibrinolysis for Acute Myocardial Infarction
Background: In Canada, most patients with acute myocardial infarction (AMI) present to hospitals without cardiac catheterization facilities. Thrombolytic therapy remains the standard-of-care in these centres.
- Trial name
- NCT00164190
- Testing
- Routine Early Percutaneous Coronary Intervention after Thrombolysis
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Canadian Heart Research Centre
Psychological Distress, Type D Personality
Efficacy of Acceptance and Commitment Therapy for the Management of Quality of Life in Patients Post Myocardial Infarction
The present study aims to investigate the efficacy of acceptance and commitment therapy for the management of quality of life in patients post-myocardial infarction
- Conditions
- Psychological Distress, Type D Personality, Medication Adherence, Quality of Life
- Trial name
- NCT06548282
- Testing
- Acceptance and commitment therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Fatima Jinnah Women University
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital
Coronary Artery Disease, Acute Myocardial Infarction
LV Thrombus Pilot Study for Comparing Enoxaparin Vs. Warfarin
To prospectively evaluate the utility of enoxaparin vs. oral warfarin in reduction of echocardiographic indices of LV mural thrombus. The primary outcome is the presence of LV mural thrombus at 3.5 months.
- Trial name
- NCT00321009
- Testing
- Enoxaparin
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Corewell Health East
Myocardial Infarction
A Study to Evaluate the Impact of Long-term Digital Education vs Standard of Care on LDL-C Levels in Post Myocardial Infarction Patients
The purpose of this study was to demonstrate the impact of digital education on the cardiovascular risk factors in post-Myocardial Infarction patients and to generate evidence for broad implementation of the proposed education…
- Trial name
- DEDUCA-CZ (NCT06548555)
- Testing
- systematic educational intervention
- Where
- 5 sites in Czechia
- Volunteers
- 121 people
- Sponsor
- Novartis Pharmaceuticals
Left Ventricular Remodeling, Acute Myocardial Infarction
Danlou Tablets to Prevent Left Ventricular Remodeling
Danlou tablets are Chinese patent medicine which has been approved in China for the treatment of ischemic heart disease, but the evidence supporting its efficacy on cardiac remodeling remains unclear.
- Trial name
- NCT02675322
- Testing
- Danlou Tablets
- Volunteers
- 82 people
- Sponsor
- shuai Mao
STEMI
Short Course Low Dose Oral Colchicine After ST Elevation Myocardial Infarction(STEMI)
To Study Efficacy and safety oral colchicine 0.6 mg post ST Elevation myocardial infraction (STEMI)
- Trial name
- NCT06020300
- Testing
- Oral Colchicine 0.6 mg, Oral Pyridoxine 10 mg
- Where
- Malaysia
- Volunteers
- 64 people
- Sponsor
- National University of Malaysia
Coronary Artery Disease, Acute Coronary Syndrome
Colchicine in Patients Undergoing Coronary Artery Bypass Grafting After Acute Coronary Syndrome
The present study seeks to evaluate the effectiveness of the use of perioperative colchicine with regard to operative complications, in patients with acute coronary syndrome and indication for cardiac post-surgical…
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Coronary Artery Bypass, Myocardial Reperfusion
- Trial name
- COCAR (NCT05726019)
- Testing
- Colchicine
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
ST-elevation Myocardial Infarction (STEMI)
The Impact of Post Stenting Balloon Dilatation on Coronary Microcirculation in STEMI Patients Undergoing PPCI
This study aims to assess the impact of NC balloon post-dilatation on coronary microcirculation in patients with ST segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).
- Trial name
- POSTDILSTEMI (NCT02788396)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Myocardial Infarction, Death, Sudden, Cardiac
Assessment of Noninvasive Methods to Identify Patients at Risk of Serious Arrhythmias After a Heart Attack
This study evaluates the usefulness of noninvasive tests of the structure of the heart and the nervous system controlling the heart.
- Conditions
- Myocardial Infarction, Death, Sudden, Cardiac, Death
- Trial name
- NCT00399503
- Testing
- Spectral T Wave Alternans, Modified Moving Average T Wave Alternans, Baroreceptor Sensitivity
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- University of Calgary
Post-myocardial Infarction Ventricular Tachycardia
Facilitating Catheter Guidance to Optimal Site for VT Ablation
Each year in the UK, approximately 150,000 people have a heart attack when the blood supply to their heart is compromised. As a result, affected regions of the heart can become diseased and scarred.
- Trial name
- CPS (NCT03862989)
- Testing
- Radiofrequency catheter ablation
- Where
- United Kingdom
- Sponsor
- University of Exeter
ST Segment Elevation Myocardial Infarction, Left Ventricular Thrombus
Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant
Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events.
- Trial name
- EARLYmyo-LVT (NCT03764241)
- Testing
- Rivaroxaban, Vitamin K Antagonist
- Where
- China
- Volunteers
- 280 people
- Sponsor
- RenJi Hospital
Acute Myocardial Infarction
Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate in STEMI Patients
Prasugrel and ticagrelor, new P2Y12-ADP receptor antagonists, are associated with greater pharmacodynamic inhibition and reduction of cardiovascular events in patients with an acute coronary syndrome.
- Trial name
- ECCLIPSE-STEMI (NCT02929888)
- Testing
- Lysine Acetilsalicilate, Aspirin
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Myocardial Infarction
Mindful Movement Intervention for Post-MI Patients
This study evaluates the feasibility and acceptability of a 12-week Tai Chi intervention for patients who have recently had a heart attack and are not participating in a standard cardiac rehabilitation program.
- Trial name
- HeartChi (NCT02297737)
- Testing
- Tai Chi, Health Education
- Volunteers
- 75 people
- Sponsor
- San Diego Veterans Healthcare System