Clinical trials: Post Operative Analgesia
Pain, Shoulder, Post Operative Pain
The Role of Neurofeedback Training and Pain Management in Post-operative Shoulder Rehabilitation
The primary aim is to compare the efficacy of neurofeedback training (NFT) and pain management protocol (PMP) in pain reduction, restoration of shoulder function, and improved cognitive performance as the post-operative…
- Trial name
- NCT05948007
- Testing
- Neurofeedback training, Pain management protocol
- Sponsor
- Chang Gung Memorial Hospital
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Post Operative Analgesia
Effect of Intraperitoneal Bupivacaine with Dexmedotomidine or Fentanyl for Post-Operative Analgesia Following Laparoscopy in Pediatric Patients
To compare analgesic effect of adding dexmedomedin or fentanyl to intraperitoneal bupivacain in pediatric patients undergoing laparoscopy.
- Trial name
- NCT06694207
- Testing
- Intraperitoneal Bupivacaine with Dexmedotomidine or Fentanyl
- Volunteers
- 80 people
- Sponsor
- Assiut University
Head and Neck Surgery, Maxillofacial Surgery
Impact of Nociception Level (NOL)-Guided Remifentanil Infusion on Intraoperative Arterial Pressure and Vasopressor Necessity
The aim of this study is to determine if Nociception Level (NOL)-guided Remifentanil analgesia, combined with Entropy-guided Propofol anesthesia, has a significant beneficial effect on the incidence of intraoperative hypotension…
- Trial name
- NCT04963036
- Testing
- Entropy and NOL-Guided Goal Directed Anesthesia, Standard of Care Group (Entropy and blinded NOL)
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Mixed Hemorrhoids, Milligan-Morgan Hemorrhoidectomy
Efficacy of Methylene Blue Plus Ropivacaine for Post-Hemorrhoidectomy Pain.
Revised Translation (Academic English): As one of the most prevalent anorectal disorders, mixed hemorrhoids continue to rely on the Milligan-Morgan hemorrhoidectomy as the gold-standard surgical approach.
- Conditions
- Mixed Hemorrhoids, Milligan-Morgan Hemorrhoidectomy, Methylene Blue
- Trial name
- NCT07164807
- Testing
- Methylene Blue (0.3%) with Ropivacaine Hydrochloride (0.75%), Methylene Blue (0.1%) with Ropivacaine Hydrochloride (0.75%)
- Where
- China
- Volunteers
- 177 people
- Sponsor
- The Affiliated Hospital of Putian University
Hindfoot Surgery, Analgesia
Postoperative Analgesia Using a Perineural Catheter Versus a Single Nerve Block in Rearfoot Surgery
Postoperative pain following hindfoot surgery is often severe and can persist for several days. It frequently leads to the use of systemic analgesics, particularly opioids, whose adverse effects are well known.
- Conditions
- Hindfoot Surgery, Analgesia, Perineural Catheter
- Trial name
- CATHORNOT (NCT07638514)
- Testing
- Phone contact, perineural catheter, Regional Anesthesia
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Laparoscopic Colecctomy
Ultrasound Guided Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection
The purpose of this study is to determine whether the transversus abdominis plane (TAP) blocks are effective in postoperative pain control of adult patients undergoing laparoscopic colectomy.
- Trial name
- NCT01423292
- Testing
- Ultrasound Guided Transversus Abdominis Plane (TAP) Block, bupivacaine
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- National Cancer Center, Korea
Nerve Block/Methods
Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients.
The goal of this clinical trial is to determine which regional block provides superior analgesia in pediatric patients undergoing thoracic surgery.
- Trial name
- NCT07796399
- Testing
- Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Appendicectomy, Postoperative Analgesia
Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block for Open Abendectomy Surgery
this aim of this study is to compare the analgesic effect of Erector spinae plane (ESP) block and lateral transversus abdominis plan (TAP) block in patients undergoing open appendectomy.
- Conditions
- Appendicectomy, Postoperative Analgesia, Regional Anaesthesia
- Trial name
- NCT07351253
- Testing
- Erector Spinae Plane Block, Transversus abdominis plane (TAP) block
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Cesarean Section, Spinal Anesthesia
Comparison of Three Different Doses of Intrathecal Morphine for Analgesia After Cesarean Section
In our study, It was aimed to determine the dose of morphine that provides the most effective analgesia with the least incidence of side effects in the postoperative period.
- Conditions
- Cesarean Section, Spinal Anesthesia, Postoperative Analgesia
- Trial name
- NCT05317572
- Testing
- 80 mcg intrathecal morphine, 120 mcg intrathecal morphine, 160 mcg intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Post-operative Pain, Acute, Opioid Use, Unspecified
Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain…
- Conditions
- Post-operative Pain, Acute, Opioid Use, Unspecified, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT06469177
- Testing
- Pain Coach App
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Post Operative Pain Control, PONV
Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients…
- Trial name
- NCT07513012
- Testing
- Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- King Edward Medical University
Postoperative Pain
The Ketamine for Acute Postoperative Analgesia (KAPA) Trial
Postoperative pain remains an important challenge for both patients and clinicians. Despite advances in pain management techniques, many patients continue to describe their pain as moderate to severe immediately after surgery.
- Trial name
- KAPA (NCT04646694)
- Testing
- Ketamine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Postoperative Pain
Efficacy of Extended-Release Liposomal Bupivacaine for Post-Operative Urogynecologic Surgery
To study post-operative efficacy of Exparel® for pain control in patients undergoing any Urogynecology surgery involving the posterior vaginal wall using a randomized, double-blinded placebo controlled trial.
- Trial name
- NCT02287246
- Testing
- Extended-Release liposomal bupivacaine (Exparel), Normal saline
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Modified Radical Mastectomy, Postoperative Analgesia
Mid-point Transverse Process to Pleura Block VS Serratus Anterior Plane Block for Postoperative Analgesia After Modified Radical Mastectomy
This study aimed to compare the analgesic efficacy of ultrasound-guided mid-point transverse process-to-pleura block versus serratus anterior plane block after unilateral modified radical mastectomy.
- Conditions
- Modified Radical Mastectomy, Postoperative Analgesia, Mid-point Transverse Process to Pleura Block, Serratus Anterior Plane Block
- Trial name
- NCT06625879
- Testing
- Serratus Anterior Plane Block (SAPB), Midpoint transverse process to pleura (MTP) block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Caudal Block for Postoperative Analgesia
Comparison of Optic Nerve Sheath Diameter in Children Receiving Caudal Block According to Anesthetic Agents: Total Intravenous Anesthesia vs. Volatile Anesthesia
Caudal block is commonly used for postoperative analgesia in paediatric patients. A higher volume (1.5 ml/kg) of local anaesthetic for caudal block has been reported to not only increase the level of cranial spread but also…
- Trial name
- NCT04415905
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Knee Replacement, Postoperative Pain
Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty
The concern for the opioid use in the total knee arthroplasty continues to rise in recent decades. Historically, the total knee arthroplasty consumed high doses opioids in the postoperative periods.
- Conditions
- Knee Replacement, Postoperative Pain, Opioid Use
- Trial name
- NCT04314505
- Testing
- Opioid-Sparing Protocol, Opioid-Based Patient Controlled Analgesia
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pain Management, Arthroplasty Total Hip Replacement
QLESP Block Versus PENG+LFCN Block for Total Hip Arthroplasty
Total hip arthroplasty (THA) is a common surgery to replace damaged hip joints, but many patients experience significant pain after surgery, which can delay recovery and increase the need for strong pain medications (opioids).
- Trial name
- QLESP (NCT07771829)
- Testing
- QLESP Block, PENG+LFCN Block, ropivacaine
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Huazhong University of Science and Technology
Postoperative Pain
Quadratus Lumborum Block vs Tranversus Abdominis Plane Block for Cesarean Section
The Quadratus Lumborum block (QLB) was first described by Blanco in 2007. The main advantage of QLB compared to the Transversus Abdominis Plane block (TAP) is the extension of local anesthetic agent beyond the TAP plane to the…
- Trial name
- NCT02489851
- Testing
- Quadratus Lumborum block, Tranversus Abdominis plane block
- Where
- United Arab Emirates
- Volunteers
- 76 people
- Sponsor
- Corniche Hospital
Post Operative Pain
Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management
This is a randomized controlled trial involving 170 opioid naive women ages 19-40 undergoing scheduled C-sections at Carilion Roanoke Memorial Hospital.
- Trial name
- NCT05360433
- Testing
- Oxycodone oral capsule
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic