Clinical trials: Post Operative Atrial Fibrillation
Atrial Fibrillation
Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial Fibrillation
After surgery on the lungs or esophagus, 12-46% of patients experience an irregular heart rhythm called atrial fibrillation. Although usually transient, post-operative atrial fibrillation is associated with longer stay in…
- Trial name
- PREP-AF (NCT04392921)
- Testing
- Amiodarone
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Post-operative Atrial Fibrillation
Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery
Metoprolol is frequently administered to cardiac surgery patients to reduce the incidence of postoperative atrial fibrillation (PoAF).
- Trial name
- PREEMPTIVE (NCT03943927)
- Testing
- Guided Metoprolol Management
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Postoperative, Atrial Fibrillation
BRS and Outcomes in Cardiothoracic Surgery
The purpose of this study is to determine whether baroreceptor sensitivity (the ability of your body to change your heart rate and/or blood pressure in response to a situation) has any effect on how likely you are to suffer…
- Conditions
- Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
- Trial name
- NCT03243279
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Atrial Fibrillation, Coronary Artery Bypass Grafting
Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)
The purpose of this study is to determine whether postoperatively oral treatment with high dosis amiodarone for five days after intravenously admitted bolusinfusion will minimize the risk for development of atrial fibrillation…
- Trial name
- NCT00287209
- Testing
- Amiodarone
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Atrial Fibrillation, Atrial Flutter
Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery
Atrial Fibrillation (AF) is a common postoperative complication of cardiac surgery, occuring in approximately 25-30% of coronary artery bypass graft (CABG) patients and 35-40% of heart valve repair/replacement patients.
- Trial name
- NCT00953212
- Testing
- beta blockers, amiodarone, ascorbic acid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- MaineHealth
Myocardial Reperfusion Injury, Atrial Fibrillation
Inhaled Sevoflurane Compared to Intravenous Sedation Post Coronary Artery Bypass Grafting
Inhaled sevoflurane during coronary artery bypass grafting (CABG) reduces postoperative Troponin levels and may be associated with improved outcome.
- Trial name
- NCT00484575
- Testing
- Sevoflurane, propofol
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Persistent Atrial Fibrillation
Pulsed Field Ablation Versus Radiofrequency Ablation: Effects of Pulmonary Vein Isolation Combined With Left Atrial Posterior Wall Isolation on Postoperative Gastric Motility in Patients With Persistent Atrial Fibrillation
This is a single-center, prospective, matched cohort study comparing the effect of Pulsed Field Ablation (PFA) versus Radiofrequency Ablation (RF) on postoperative gastric motility in patients with persistent atrial fibrillation…
- Trial name
- PFA-GM (NCT07612241)
- Testing
- Pulsed Field Ablation, Radiofrequency Ablation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Post-operative Atrial Fibrillation, Cardiovascular Diseases
Association Between GalectiN-3 and pOSt-operative atrIal Fibrillation After Coronary Artery bypaSs Graft
The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG).
- Conditions
- Post-operative Atrial Fibrillation, Cardiovascular Diseases, Post-pericardiotomy Syndrome
- Trial name
- GNOSIS (NCT06768528)
- Testing
- Galectin-3 dosage
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Atrial Fibrillation (AF), Catheter Ablation
PROMBot-HSM-FA: Protocol for a Feasibility Study of a Chatbot Platform to Collect Patient-reported Outcomes After AF Ablation
The goal of this clinical trial is to learn if using a WhatsApp-based chatbot called PROMBot-FA can help people recover after atrial fibrillation ablation.
- Trial name
- PROMBot-HSM-FA (NCT07237178)
- Testing
- PROMBot-FA Chatbot-Supported Follow-Up, Standard Care (in control arm)
- Volunteers
- 76 people
- Sponsor
- Ana Rita Londral, PhD
Postoperative Delirium (POD), Postoperative Bleeding
GENECARD - the Use of Genetic, Epigenetic, Metabolomic, Proteomic and Microbiotic Markers, Image and Voice Biomarker Analyses, and Pre- and Intraoperative Clinical Data - to Predict Early Complications After Cardiac Surgery.
The goal of this observational cohort study is to prove whether genetic, epigenetic, transcriptomic, proteomic, metabolomic, imaging, voice, and clinical markers can improve prediction of early complications after cardiac surgery…
- Conditions
- Postoperative Delirium (POD), Postoperative Bleeding, Acute Kidney Injury, Atrial Fibrillation (AF)
- Trial name
- GENECARD (NCT07345403)
- Testing
- Multi-Omics Data and Clinical Data Collection
- Where
- Poland
- Volunteers
- 3,000 people
- Sponsor
- Medical University of Gdansk
Atrial Fibrillation
Amiodarone to Prevent Post-Operative Arrhythmias
Rapid heart rhythms originating from the upper heart chambers (atrial tachyarrhythmias) are very common after open-heart surgery.
- Trial name
- NCT00251706
- Testing
- amiodarone
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Calgary
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Atrial Fibrillation
Transcutaneous (Tragus) Vagal Nerve Stimulation for Post-op Afib
Patients undergoing cardiac surgery are at high risk of developing atrial fibrillation (AF), with estimated rates of 30-50% and occurs at approximately 2-4 days after surgery.
- Trial name
- STOP_AF (NCT04514757)
- Testing
- active tVNS
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of California, Los Angeles
Atrial Fibrillation
Post-operative Corticosteroid Treatment After Mitral Valve Surgery
The aim of the study is to intestigate whether three days intravenous corticosteroid management prevent atrial fibrillations in adults after mitral valve surgery.
- Trial name
- MitralPOCS (NCT03682393)
- Testing
- Hydrocortisone
- Where
- Finland
- Sponsor
- Kuopio University Hospital
Pulmonary Embolism, Atrial Fibrillation
Study to Find Out the Appropriate Initial Dose of the Anticoagulant Drug Phenprocoumon
Oral anticoagulation is often initiated in hospitalized patients. Although the therapeutic range of phenprocoumon is narrow, the individual drug demands unfortunately vary greatly between persons.
- Conditions
- Pulmonary Embolism, Atrial Fibrillation, Hip Replacement Postoperative, Knee Replacement Postoperative
- Trial name
- NCT00586287
- Testing
- Algorithm for phenprocoumon, Phenprocoumon
- Where
- Switzerland
- Volunteers
- 302 people
- Sponsor
- Cantonal Hospital of St. Gallen
Post-operative Atrial Fibrillation (POAF)
Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation
Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery and leads to worse outcomes. POAF is thought to be caused by the inflammatory state following cardiac surgery.
- Trial name
- NCT05991700
- Testing
- Freeze-Dried California Table Grape
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Michigan
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Atrial Fibrillation
Postoperative Atrial Fibrillation Suppression By Nerve Stimulation
The current study will evaluate the potential of stimulating the R.auricularis of the vagus nerve located at the Fossa triangularis to ameliorate or suppress AF in the study Population!
- Trial name
- NCT03533140
- Testing
- DUCEST Neurostimulator V Group A, DUCEST Neurostimulator V Group B
- Volunteers
- 42 people
- Sponsor
- Medical University of Vienna
Atrial Fibrillation
The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery-Extended Follow-Up
The purpose of the Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery (PALACS, NCT02875405) trial was to determine if performing posterior left pericardiotomy at the time of cardiac…
- Trial name
- PALACS-EF (NCT05903222)
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Weill Medical College of Cornell University
Atrial Fibrillation, Cardiac Surgery
Postoperative New-onset Atrial Fibrillation in Cardiac Surgery: DECS-PNAF Project
The DExamethasone for Cardiac Surgery - Postoperative New-onset Atrial Fibrillation (DECS-PNAF) project described in this protocol aims to elucidate how corticosteroids protect cardiac surgical patients from Postoperative…
- Trial name
- DECS-PNAF (NCT01143129)
- Testing
- Dexamethasone
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- UMC Utrecht