Clinical trials: Post Operative Atrial Fibrillation, open to volunteers
Atrial Fibrillation, Stroke
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who…
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Trial name
- PACES (NCT04045665)
- Testing
- Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy
- Where
- 106 sites in United States, Brazil and 3 more
- Volunteers
- 3,200 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Coronary Syndrome, Atrial Fibrillation
SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF
The goal of this randomized, double-blinded, controlled clinical trial is to investigate if treatment with an sodium-glucose cotransporter-2 inhibitor (SGLT2) during the unique time window before coronary artery bypass surgery…
- Trial name
- STENOTYPE (NCT05852704)
- Testing
- Dapagliflozin 10mg Tab
- Where
- 8 sites in Czechia, Denmark and 1 more
- Volunteers
- 800 people
- Sponsor
- Region Örebro County
Surgery, Cardiac, Atrial Fibrillation
Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Postoperative atrial fibrillation is quite common after cardiac surgery with up to 1 in 3 patients experiencing this abnormal heart rhythm.
- Trial name
- PATRONUS (NCT05543278)
- Testing
- Amiodarone
- Volunteers
- 242 people
- Sponsor
- Massachusetts General Hospital
Postoperative Atrial Fibrillation, Thoracic Surgery
Diagnosis of Atrial Fibrillation in Postoperative Thoracic Surgery Using a Smartwatch
Postoperative atrial fibrillation (POAF) occurs in approximately 20% of patients following thoracic surgery. Early diagnosis is essential to prevent complications such as heart failure, stroke, myocardial infarction, and…
- Conditions
- Postoperative Atrial Fibrillation, Thoracic Surgery, Smartwatches, Rhythm Monitoring
- Trial name
- THO-FA-WATCH (NCT06724718)
- Testing
- smartwatch, ECG
- Where
- France
- Volunteers
- 302 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Atrial Fibrillation, Atrial Flutter
Pericardiotomy in Cardiac Surgery
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Cardiac Events
- Trial name
- PRINCE (NCT06486636)
- Testing
- Left Posterior Pericardiotomy
- Where
- 19 sites in United States, Austria and 3 more
- Volunteers
- 1,400 people
- Sponsor
- Population Health Research Institute
Postoperative Atrial Fibrillation, Lung Surgery
Perioperative Statins to Prevent AFib After Lung Surgery
The goal of this clinical trial is to learn whether short-term treatment with atorvastatin can prevent new abnormal rapid heart rhythms after lung surgery in adults aged 60 years or older who are scheduled to have a lung segment…
- Trial name
- STAT-LUNG (NCT07727681)
- Testing
- Atorvastatin
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation, Cardiac Surgery
Diagnosis of Postoperative Atrial Fibrillation by a Smartwatch
The incidence of postoperative atrial fibrillation (POAF) after on-pump cardiac surgery remains high, at around 30%. POAF increases the risk of cardiac decompensation, stroke, acute myocardial infarction, and death, resulting in…
- Trial name
- FAWATCH (NCT05573633)
- Testing
- ECG, scanwatch
- Where
- France
- Volunteers
- 324 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Atrial Fibrillation, Atrial Fibrillation, Persistent
Electrical Cardioversion As a Predictor in Postoperative Preservation of Sinus Rhythm
The aim of this study is to evaluate benefits of electric cardioversion in the early and long-term postoperative period in patients after radiofrequency catheter isolation of pulmonary veins.
- Trial name
- NCT06654401
- Testing
- Transthoracic echocardiography, 24-hour ECG Monitor, Electroanatomic mapping
- Where
- Russia
- Volunteers
- 125 people
- Sponsor
- Saint Petersburg State University, Russia
Atrial Fibrillation, Atrial Arrhythmia
Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall…
- Conditions
- Atrial Fibrillation, Atrial Arrhythmia, Atrial Flutter, Atrial Tachycardia
- Trial name
- NCT05014802
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Left Atrial Appendage Thrombosis
The Left Atrial Appendage Closure by Surgery and the Incidence of Stroke in Patients Undergoing Open-heart Surgery.
This study aims to assess the efficacy and safety of prophylactic surgical closure of the left atrial appendage for stroke and cardiovascular death prevention in patients undergoing open heart surgery, regardless of their…
- Trial name
- NCT06172738
- Testing
- the left atrial appendage closure through surgery.
- Volunteers
- 100 people
- Sponsor
- Assiut University
Colchicine, Inflammation in Cardiac Surgery
Colchicine's Effect on Inflammatory Markers
This study wants to see if the medicine colchicine can help lower inflammation and reduce the chance of developing an irregular heartbeat (atrial fibrillation) after heart bypass surgery.
- Conditions
- Colchicine, Inflammation in Cardiac Surgery, Post Operative Atrial Fibrillation, Inflammatory Markers
- Trial name
- NCT07287345
- Testing
- Colchicine (Colcrys®)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ayesha Ather
Postoperative Atrial Fibrillation
Prophylactic Radiofrequency Left Atrial Posterior Wall Isolation to Prevent Atrial Fibrillation After Cardiac Surgery
The goal of this clinical trial is to learn if an epicardial radiofrequency left atrial posterior wall isolation (box lesion ablation) prevents atrial fibrillation after cardiac surgery.
- Trial name
- PROBOX (NCT06823778)
- Testing
- Radiofrequency ablation
- Where
- Russia
- Volunteers
- 216 people
- Sponsor
- Vasily I. Kaleda
Postoperative Atrial Fibrillation
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement
Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery.
- Trial name
- STARC (NCT05076019)
- Testing
- Atorvastatin 80mg
- Where
- Denmark
- Volunteers
- 266 people
- Sponsor
- Odense University Hospital