Clinical trials: Post Operative Complications
Esophageal Diseases, Esophagostomy Complication
Implementing Enhanced Recovery After Surgery (ERAS) Protocol in Patients Undergoing Minimal Invasive Esophagectomy
Detect impact of enhanced recovery after surgery (ERAS) on the outcomes of oesophageal surgery .
- Trial name
- NCT06243887
- Testing
- Enhanced Recovery After Surgery (ERAS) protocol in minimal invasive esophagectomy, standard of care approaches in minimal invasive esophagectomy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Diaphragm Issues, Neurosurgery
Post-neurosurgical Respiratory Muscle Dysfunction
Respiratory muscle dysfunction may contribute to the development of postoperative pulmonary complications. However, it prevalence in patients receiving neurosurgery is largely unknown.
- Conditions
- Diaphragm Issues, Neurosurgery, Pulmonary Complication
- Trial name
- NCT05951114
- Testing
- Maximum inspiratory/Expiratory manoeuvre for patients can follow the order
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Sanbo Brain Hospital
Inguinal Hernia Unilateral
Comparison of Quadro-Iliac Plane Block and Transversalis Fascia Plane Block for Open Inguinal Hernia Repair
This prospective observational cohort study aims to compare the postoperative analgesic effectiveness of the quadro-iliac plane block (QIPB) and transversalis fascia plane block (TFPB) in patients undergoing elective unilateral…
- Trial name
- NCT07864064
- Testing
- Quadro iliac Plane Block, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Vezirköprü State Hospital
Laparoscopic Cholecystectomy, Postoperative Nausea
The Effect of Cold Vapor on Nausea and Vomiting in the Early Postoperative Period After Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) was defined by the American Society of PeriAnesthesia Nurses (ASPAN) as nausea and/or vomiting in the first 24 hours after surgery and is among the most common complications after pain in…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT05302128
- Testing
- Cold vapor
- Volunteers
- 84 people
- Sponsor
- Istanbul Medeniyet University
Postoperative Pain, Gastrointestinal Motility Disorder
The Effect of Foot Reflexology After Cesarean Section
Standardized, quality and evidence-based nursing care after cesarean section is important to prevent or minimize complications that may occur after cesarean section.
- Trial name
- NCT05268328
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nülüfer Erbil
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Thoracic Paravertebral Block, Erector Spinae Plane Block, and in Combined Paravertebral-erector Spinae Block
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Thoracic Surgery, Video-Assisted, Thoracic Paravertebral Block, Erector Spinae Plane Block
- Trial name
- NCT04929665
- Testing
- Two different block and combination of these two blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Analgesia
Extended Delivery of Bupivacaine Study in Herniorrhaphy
This is a phase 4, randomized, open-label study of the efficacy, safety, and pharmacokinetics of bupivacaine administered as liposomal bupivacaine or continuous infusion via elastomeric pump following unilateral open inguinal…
- Trial name
- NCT04102267
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine HCl without epinephrine via continuous infusion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Anxiety Acute, Emergence Agitation
Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery
The goal of this clinical trial is to compare between the effect of nebulized dexmedetomidine and the effect of oral dispensable film (ODF) melatonin in controlling perioperative anxiety and post operative emergence agitation and…
- Trial name
- NCT05766436
- Testing
- Dexmedetomidine, Melatonin
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- nada moahmed aboelrouse
Postoperative Pain
An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours
To compare the incidence and severity of nausea in the study treatment groups, during the 18-hour period starting 6 hours after titration to pain relief; following confirmation of the assumption of non-inferiority between the two…
- Trial name
- NCT01082471
- Testing
- Morphine 6-glucuronide, Morphine
- Where
- 7 sites in Czechia, France and 4 more
- Volunteers
- 517 people
- Sponsor
- Paion UK Ltd.
Postoperative Nausea, Postoperative Vomiting
Intravenous Fluids After Laparoscopic Cholecystectomy
Perioperative intravenous fluid (IV) administration has been the standard procedure since 1832 and, is a widely used practice sometimes under inadequate criteria.
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Renal Function Abnormal, Hunger
- Trial name
- NCT03142464
- Testing
- Suspension of the IV fluids
- Volunteers
- 100 people
- Sponsor
- Federal University of Minas Gerais
Aortic Coarctation, Retrospective Studies
Prevalence and Risk Factors for Hypertension and Recoarctation in Patients Operated for Aortic Coarctation
Multicenter Retrospective Study Over a 14-Year Period From 2010 to 2024
- Conditions
- Aortic Coarctation, Retrospective Studies, Cohort Studies, Hypertension
- Trial name
- PRECOHA (NCT07499609)
- Where
- France
- Volunteers
- 901 people
- Sponsor
- Institut Saint Pierre
Kidney Cancer
Sunitinib Before or After Surgery in Treating Patients With Metastatic Kidney Cancer
RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00626509
- Testing
- sunitinib malate, adjuvant therapy, neoadjuvant therapy
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Gruppo Italiano Carcinoma Renale
Pain, Postoperative, Abdominal Surgery
Erector Spinae Plane Block Versus Oblique-Subcostal Transversus Abdominis Plane Block in Emergency Abdominal Surgery with Midline Incision
Most of the recommendations regarding pain management in emergency abdominal surgery are extracted from data from elective abdominal surgery.
- Conditions
- Pain, Postoperative, Abdominal Surgery, Emergency
- Trial name
- NCT06448299
- Testing
- TAPB, ESPB
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain
Gabapentin and Diclofenac Sodium Comparison for Post-Operative Pain Relief
Little is known about comparative efficacy of gabapentin and diclofenac sodium in managing post-operative pain. Therefore, this study was planned to compare the efficacy of gabapentin, and diclofenac sodium for post-operative…
- Trial name
- NCT07267182
- Testing
- Gabapentin 600mg, Diclofenac Sodium 100 MG
- Where
- Pakistan
- Volunteers
- 240 people
- Sponsor
- Muhammad Aamir Latif
Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury
Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery
Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury, Postoperative Complications, Risk Stratification
- Trial name
- NCT07598682
- Testing
- Early Postoperative Phenotype Classification
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Postoperative Pain, Obstetric Pain
Lidocaine Patches After Cesarean Section
The aim of this study is to investigate the impact of using lidocaine patches after cesarean section on pain control and opioid use in the immediate post-operative period.
- Conditions
- Postoperative Pain, Obstetric Pain, Opioid Use
- Trial name
- LPACS (NCT04443569)
- Testing
- Lidocaine patch
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Yale University
Newborn Morbidity, Oral Aversion
Sham Feeding Post-operative Infants
The purpose of this pilot study is to evaluate a feeding technique, sham feeding, to promote adequate oral skills in order to prevent oral aversion and/or poor oral skills due to the delay in oral feeds for surgical reasons.
- Conditions
- Newborn Morbidity, Oral Aversion, Gastroschisis, Bowel Obstruction
- Trial name
- NCT03350022
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Le Bonheur Children's Hospital
Renal Cell Carcinoma
A Study of Anti-PD1 (Nivolumab) Therapy as Pre- and Post-operative Therapy in Metastatic Renal Cell Cancer (ADAPTeR)
Single arm, open label, phase II trial. Participants to undergo biopsy of primary tumour followed by 8 weeks of nivolumab therapy followed by nephrectomy. Nivolumab to be continued post-operatively
- Trial name
- ADAPTeR (NCT02446860)
- Testing
- nivolumab
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Postoperative Pain After Breast Reconstruction With Abdominal Flap
Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction
The aim of this randomized, double-blind controlled trial is to determine the efficacy of transdermal fentanyl for the management of early postoperative pain in women undergoing mastectomy followed by immediate TRAM or DIEP flap…
- Trial name
- Fentanyl Patch (NCT01258296)
- Testing
- Fentanyl, Inactive patch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Postoperative Nausea and Vomiting
Effect of Ramosetron on Bowel Motility After Colorectal Resection
Ramosetron is effective in preventing postoperative nausea and vomiting. Several studies reported that ramosetron is also effective treatment diarrhea-predominant irritable bowel syndrome.
- Trial name
- NCT01427127
- Testing
- Ramosetron
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Kyunghee University Medical Center
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