Clinical trials: Post Operative Complications
Abdominal Wall Defect, Incisional Hernia
Change in Fascial Tension in Open Abdomens
The goal of this observational study is to quantitatively measure the change in tension of the abdominal wall over time in subjects with open abdomens using a tensiometer.
- Trial name
- NCT05579652
- Testing
- Abdominal tension measurement
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Miller
Esophageal Neoplasms, Esophagectomy
Effect of Neck Flexion on Esophagogastric Anastomotic Leakage After MIE
Esophageal cancer (EC) is the eighth most common cancer and the sixth leading cause of cancer deaths worldwide. Minimally invasive esophagectomy (MIE) is regarded as a safe and effective management for resectable EC.
- Conditions
- Esophageal Neoplasms, Esophagectomy, Anastomotic Leak
- Trial name
- NCT02418052
- Testing
- neck flexion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Vasoplegia, Hypotension
Hemodynamic Effects of Methylene Blue vs Hydroxocobalamin in Patients at Risk of Vasoplegia During Cardiac Surgery
This is a pilot study to determine the hemodynamic effects when hydroxocobalamin vs methylene blue is administered during cardiopulmonary bypass in patients at risk of vasoplegia by measuring mean arterial pressure (MAP)…
- Conditions
- Vasoplegia, Hypotension, Coronary Artery Disease, Cardiac Valve Disease
- Trial name
- NCT03446599
- Testing
- Hydroxocobalamin, Methylene Blue, Normal saline
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Postoperative Cognitive Dysfunction (POCD)
Intravenous Anesthesıa and Cognıtıve Functıon ın Spınal Surgery
The aim of this study is to investigate the effect of these two different intravenous infusion techniques [manuel controlled infusion (MCI) and Target controlled Infusion( TCI)] on POCD.
- Trial name
- NCT07701187
- Testing
- Manuel controlled infusion group
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Post Operative Pain
PENG Block in Comparison With Anesthetic Infiltration (PAI) After Hip Hemiarthroplasty
The goal of this intervention study is to compare the analgesic efficacy of pericapsular nerve group (PENG) block versus periarticular anesthetic infiltration (PAI) block in patients undergo hemiarthroplasty after spinal…
- Trial name
- NCT06677606
- Testing
- PENG block, PAI block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Thumb Basal Joint Osteoarthritis, Postoperative Pain
Journavx to Treat Pain After Thumb Basal Joint Arthroplasty
The purpose of this study is to find out how well suzetrigine, a newly FDA-approved non-opioid pain medication, works to relieve pain after thumb basal joint replacement surgery.
- Conditions
- Thumb Basal Joint Osteoarthritis, Postoperative Pain, Joint Replacement Surgery, Joint Replacement
- Trial name
- NCT07723352
- Testing
- suzetrigine 100mg, Acetaminophen
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Pain, Phantom, Pain, Neuropathic
Valproic Acid for the Prevention of Post-Amputation Pain
The objectives of this study are, to test the effectiveness of Valproic Acid (VPA) in the prevention of chronic neuropathic and post-amputation pain, as well as to further define the underlying inflammatory and epigenetic…
- Trial name
- NCT01928849
- Testing
- Valproic Acid, Cherry Syrup
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Emergency Surgery, Surgical Site Infections
Irrisept in Emergency General Surgery Patients
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Trial name
- NCT07048899
- Testing
- Chlorhexidine, Normal Saline
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Postoperative Nausea and Vomiting (PONV)
Implementing a Nurse-Driven Aromatherapy Protocol to Decrease the Effect of Postoperative Nausea and Vomiting
This is a quality improvement project that aims to assess the effect of nurse-driven administration of essential oil aromatherapy on postoperative nausea and vomiting (PONV) in patients while in the post-anesthesia care unit…
- Trial name
- NCT04822844
- Testing
- Lavender Essential Oil, Ginger Essential Oil
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Surgical Site Infection
Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections
Use of 2% chlorhexidine gluconate cloths pre-operatively and daily post-operatively jaw line to toes will decrease surgical site infections (SSI) by 30% when compared to patients who receive routine standard of care (use of…
- Trial name
- NCT02385708
- Testing
- 2% Chlorohexidine Gluconate Standard of Care, 2% Chlorohexidine Gluconate Chin to Toe
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Vanderbilt University
Postoperative Nausea and Vomiting
Comp Granisetron Midazolam Comb in Lap Children
Postoperative nausea and vomiting (PONV) is one of the most common complications of general anesthesia in pediatrics. Pediatric rates of nausea and vomiting are approximately double those of adult patients.
- Trial name
- NCT03483350
- Testing
- Granisetron, Midazolam
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain Score
Single Port Insufflation RCT
The goal of this clinical trial is to learn if decreasing insufflation pressure during minimally invasive single port robotic sacrocolpopexy improved postoperative pain without impacting surgeon intraoperative visualization.
- Trial name
- NCT06990750
- Testing
- 15 mmHg, 12 mmHg
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Chicago
Postoperative Pain, Video-Assisted Thoracoscopic Surgery
SPSIP Block vs SAP Block for Post-VATS Pain
Comparison of Superior Serratus Posterior Intercostal Plane Block and Serratus Anterior Plane Block for Pain Management Following Video-Assisted Thoracoscopic Surgery: A Prospective Observational Cohort Study Introduction…
- Trial name
- NCT07467291
- Testing
- Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Firat University
Elective Surgical Procedures, Postoperative Pain
Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Open Abdominal Aortic Aneurysm (AAA) repair is a high-risk surgical procedure accompanied by intense endocrine and metabolic responses to surgical stress, with subsequent activation of the inflammatory cascade, cytokine and…
- Conditions
- Elective Surgical Procedures, Postoperative Pain, Anesthesia, Opioid Use
- Trial name
- NCT04894864
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Crete
Postoperative Pain, Nerve Block
Effect of Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Ankle Surgery
Effect of perineural dexamethasone on the duration of popliteal nerve block after ankle/foot surgery
- Trial name
- NCT03332316
- Testing
- Dexamethasone Sodium Phosphate, Ropivacaine Hydrochloride Inj 2 mg/ml, Sodium Chloride 9mg/mL
- Where
- Finland
- Volunteers
- 84 people
- Sponsor
- Tampere University Hospital
Hernia, Inguinal, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Surgical intervention to treat a inguinal hernia is a very common pediatric surgical procedure, often performed using an inguinal incision.
- Trial name
- NCT03041948
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- 2 sites in Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Phantom Limb Pain, Chronic Pain
Prevention of Phantom Limb Pain After Transtibial Amputation
Phantom limb pain following amputation is a major problem. Current evidence how to best prevent phantom limb pain is equivocal because previous trials have included small numbers of patients, and tested heterogeneous patient…
- Conditions
- Phantom Limb Pain, Chronic Pain, Prevention
- Trial name
- PLATA (NCT01626755)
- Testing
- Sciatic name block
- Where
- 9 sites in United States, Austria and 3 more
- Volunteers
- 12 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pain, Postoperative
Methadone for Postoperative Pain
The aim of this study is to compare the efficacy of methadone versus morphine in dealing with postoperative pain, in laparoscopic cholecystectomy under total intravenous anesthesia (TIVA); Efficacy is defined in terms of the…
- Trial name
- NCT01833715
- Testing
- Morphine, Methadone, TIVA
- Where
- Chile
- Volunteers
- 86 people
- Sponsor
- Universidad de Valparaiso
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Cesarean Section, Postoperative Recovery
Enhanced Recovery Protocol Compliance and Quality of Recovery After Cesarean Delivery
This prospective observational study will evaluate whether adherence to enhanced recovery after cesarean delivery protocols is associated with postoperative recovery quality in women undergoing elective cesarean delivery under…
- Conditions
- Cesarean Section, Postoperative Recovery, Postoperative Pain
- Trial name
- ERAC-QoR (NCT07790471)
- Testing
- Assessment of Enhanced Recovery Protocol Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
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