Clinical trials: Post Operative Complications
Shoulder Arthroscopy
Continuous Cervical Erector Spinae Plane Block Versus Interscalene Nerve Block in Shoulder Arthroscopic Surgery
Shoulder arthroscopic surgery is associated with moderate to severe postoperative pain, which may hinder early mobilization and functional recovery.
- Trial name
- NCT07369271
- Testing
- Continuous Cervical Erector Spinae Plane Block, Continuous Interscalene Block, No intervention
- Where
- Taiwan
- Volunteers
- 165 people
- Sponsor
- National Cheng-Kung University Hospital
Phantom Limb Pain
Graded Motor Imagery in Phantom Limb Pain (GraMI Protocol)
The International Association for the Study of Pain defines phantom limb pain (PLP) as that pain referred to a part of the body that has been previously removed as if it were still present.
- Trial name
- GraMI (NCT05083611)
- Testing
- GraMI
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Vic - Central University of Catalonia
Postoperative Pain
Safety of Buprenorphine Transdermal System (BTDS) in Subjects With Acute Postoperative Pain After Total Knee Replacement
The objectives in this study are to evaluate: (1) efficacy of buprenorphine transdermal system (BTDS, Butrans™) on postoperative pain following total knee replacement surgery; (2) the impact of BTDS on functional rehabilitative…
- Trial name
- NCT00403234
- Testing
- Buprenorphine transdermal patch
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Purdue Pharma LP
Bladder Cancer
Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery
The current usage of antibiotic prophylaxis (AP) in radical cystectomy (RC) is aimed to reducing the incidence of surgical site infections and incidence of unnecessary prescribing of antibiotics.
- Trial name
- MACS (NCT05392634)
- Testing
- Meropenem 1000 mg, Amoxicillin+clavulanic acid 1200 mg or Cefuroksim 1500mg
- Where
- Russia
- Volunteers
- 98 people
- Sponsor
- N.N. Petrov National Medical Research Center of Oncology
Respiratory Complication
Effects of Conventional Physiotherapy and Thoracoabdominal Rebalancing in Post-operative of Myocardial Revascularization
When it comes to cardiovascular diseases, surgical or clinical treatment can be cited, and cardiac surgery is considered a complex and large treatment where it involves important organic repercussions that alter the physiological…
- Trial name
- NCT04631198
- Testing
- Thoracoabdominal rebalancing
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Nausea and Vomiting
Transdermal Nicotine in Female Patients at High Risk for Post Operative Nausea and/or Vomiting (PONV)
The purpose of this study is to see if the nicotine patch reduces post operative nausea and/or vomiting (PONV) among non-smoking patients who are at high risk of PONV.
- Trial name
- NCT00775749
- Testing
- transdermal nicotine patch
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Postoperative Nausea and Vomiting
Aprepitant Versus Gabapentin Prophylaxis for Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgeries
To evaluate the efficacy of pre-empetive administration of Aprepitant, Versus Gabapentin prophylaxis for reducing the incidence of postoperative nausea and vomiting in Laproscopic gynacological surgeries.
- Trial name
- PONV (NCT02525848)
- Testing
- dexamethasone, Gabapentin, Aprepitant
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Mild Cognitive Impairment
The Effect of Blood Pressure on the Postoperative Cognitive Dysfunction
Permanent and temporary cognitive impairment in the perioperative period is of great importance to patients. Hypoperfusion due to the intraoperative hypotension is often mentioned as a possible cause of postoperative cognitive…
- Trial name
- NCT02536885
- Testing
- Liberal group, Restrictive group
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Hradec Kralove
Incisional Hernia, Ileostomy - Stoma
Effect of Duramesh™ on Hernia Formation After Ileostomy Closure
Diverting ileostomy is frequently utilized to protect high-risk anastomoses, though it is not shown to reduce the leak rate it may reduce the severe consequences of an anastomotic leak.
- Trial name
- NCT06511414
- Testing
- duramesh, Control
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Northwestern University
Breast Cancer Related Lymphedema, Breast Cancer-Related Arm Lymphedema
The Effects of Upper Extremity Lymphedema on Posture, Upper Extremity Functions, and Quality of Life
This study aims to examine the effects of lymphedema extremity on upper extremity function, posture and quality of life in patients who develop upper extremity lymphedema after unilateral breast cancer.
- Trial name
- NCT05776433
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Chronic Postsurgical Pain, Acute Post Operative Pain
Prediction of Chronic Postsurgical Pain in Adults
This research will be a prospective single-centre observational cohort study in Denmark spanning approximately one year. The objective of this study is to develop a clinically applicable and generalizable prediction model for…
- Trial name
- NCT04866147
- Testing
- Cardiothoracic surgery, Breast surgery, Gastrointestinal surgery
- Where
- 2 sites in Denmark
- Volunteers
- 1,522 people
- Sponsor
- University of Aarhus
Postoperative Cognitive Dysfunction
Correlations of Epigenetic Changes With POCD in Surgical Patients
Postoperative cognitive dysfunction (POCD) is a subtle cognitive dysfunction, especially postoperative memory impairment lasting for weeks or months. The underlying pathophysiological mechanism of POCD remain unclear.
- Trial name
- NCT02965235
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Central South University
Anesthesia, Nausea and Vomiting, Postoperative
Effect of Acupuncture on Postoperative Nausea and Vomiting
In this study, the hypothesis that bilateral acupuncture needling at the Neiguan (PC6) point during the intraoperative period, in addition to the 0.15 mg/kg dose of ondansetron (5-HT3 antagonist) frequently used for postoperative…
- Trial name
- NCT06669676
- Testing
- acupuncture, No acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Post Operative Pain
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
A double-blind randomized control study to compare the efficacy of dexmedetomidine versus ketamine as an adjuvant in combination with bupivacaine ultrasound-guided ESP block in patients scheduled for cardiothoracic surgeries with…
- Trial name
- NCT05552391
- Testing
- Bupivacaine, Ketamine Hydrochloride, Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kasr El Aini Hospital
Rebound Pain, Total Knee Arthroplasty
Heart Rate Variability as a Predictor of Rebound Pain Following Total Knee Arthroplasty
This study aims to investigate whether heart rate variability (HRV), a marker of autonomic nervous system activity, can predict the occurrence of rebound pain after total knee arthroplasty (TKA).
- Conditions
- Rebound Pain, Total Knee Arthroplasty, Postoperative Pain, Chronic, Heart Rate Variability
- Trial name
- NCT06977191
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Konya City Hospital
Kidney Stones
Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy
Here is a patient-friendly, ClinicalTrials.gov-compliant Brief Summary written in plain language, avoiding technical jargon as much as possible while remaining accurate.
- Trial name
- BLOCK-PCNL (NCT07359391)
- Testing
- Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Rectum Cancer, Faecal Incontinence
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023.
- Conditions
- Rectum Cancer, Faecal Incontinence, Faecal Incontinence with Faecal Urgency, Low Anterior Resection Syndrome
- Trial name
- NCT06601985
- Testing
- J-pouch anastomosis, direct anastomosis
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai 10th People's Hospital
Postoperative Delirium (POD)
Perioperative Dezocine Administration and Postoperative Delirium in Elderly Cardiac Surgery Patients
Postoperative delirium (POD) is a common complication in elderly patients undergoing cardiac surgery and is associated with prolonged hospitalization, increased morbidity, and poor recovery.
- Trial name
- NCT07768150
- Testing
- Dezocine, Normal Saline (NS)
- Where
- 2 sites in China
- Volunteers
- 640 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Smoking Cessation, Perioperative/Postoperative Complications
Perioperative Smoking Cessation Interventions
To assess impact of behavioral economic principles of precommitment, implementation intentions, and social contracting on smoking cessation for patients undergoing surgery.
- Trial name
- NCT03222908
- Testing
- Intervention1: Contract Agreement, Intervention2: Implementation Intentions
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
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