Clinical trials: Post Operative Complications
Postoperative Nausea and Vomiting, Postoperative Pain, Acute
The Correlation Between Intraoperative End Tidal Carbon Dioxide, Perfusion Index and Pulse Variability Index on Postoperative Nausea Vomiting and Pain
Postoperative pain, which is frequently encountered in laparoscopic operations, has been examined in different studies with end tidal CO2 (end tidal carbon dioxide), total insufflated gas amount and PI (Perfusion index)…
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Acute, End Tidal Carbon Dioxide, Perfusion Index and Pleth Variability Index
- Trial name
- NCT06865378
- Testing
- Carbon dioxide (CO2) gas insufflation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Naime Yalçın
Rib Fracture, Postoperative Pain
SPSIP vs ESP Block for Analgesia After Rib Fracture Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) block and the Erector Spinae Plane (ESP) block in patients undergoing surgical…
- Conditions
- Rib Fracture, Postoperative Pain, Thoracic Trauma
- Trial name
- NCT07553208
- Testing
- Erector Spinae Plane Block (ESP), Serratus Posterior Superior Intercostal Plane (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Postoperative Pain
Predictors of Postoperative Pain
The purpose of the study is to prove that pain scores generated from painful stimuli applied preoperatively may help identify the inter-individual variability in pain perception.
- Trial name
- NCT01449318
- Testing
- Thermal Sensory Analyzer (Senselab)
- Where
- 2 sites in Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Postoperative Delirium (POD), Peripheral Arterial Disease
Effect of Preoperative Ultrasound-Guided Stellate Ganglion Block on Postoperative Delirium in Older Adults Undergoing Elective Peripheral Endovascular Intervention
This randomized controlled trial will evaluate whether preoperative ultrasound-guided stellate ganglion block reduces the incidence of postoperative delirium in adults aged 60 years or older undergoing elective peripheral…
- Trial name
- NCT07848113
- Testing
- ropivacaine
- Volunteers
- 168 people
- Sponsor
- Assiut University
Knee Osteoarthritis, Persistent Postsurgical Pain
Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain
Chronic knee pain remains a disabling disease despite current treatment strategies. There is an increase in the prevalence of osteoarthritis (OA) of the knee in the general population, presently affecting approximately 450,000…
- Conditions
- Knee Osteoarthritis, Persistent Postsurgical Pain, Chronic Knee Pain
- Trial name
- COGENIUS (NCT05407610)
- Testing
- Conventional Radiofrequency ablation of the genicular nerves, Cooled Radiofrequency ablation of the genicular nerves
- Where
- 15 sites in Belgium, Netherlands
- Volunteers
- 400 people
- Sponsor
- Ziekenhuis Oost-Limburg
Postoperative Pulmonary Complications (PPCs), Cardiac Surgery in Adult Patient
Sigh Ventilation in Cardiac Surgery
The purpose of this trial is to investigate whether sigh ventilation strategy, combining sigh breaths, low tidal volume, and moderate PEEP levels, protects against major pulmonary complications within the first 7 postoperative…
- Trial name
- NCT07024420
- Testing
- Sigh Breaths, Low Tidal Volume, Moderate PEEP
- Where
- China
- Volunteers
- 686 people
- Sponsor
- Zhongda Hospital
Postoperative Pain After Laparoscopic Liver Resection
Intraoperative Continuous Lidocaine Infusion in Laparoscopic Liver Surgery
The goal of this clinical trial is to learn about effect of intraoperative continuous lidocaine infusion on postoperative pain, gut function and insulin resistance in patients undergoing laparoscopic liver surgery in adults.
- Trial name
- ICLIL (NCT07012889)
- Testing
- lidocaine infusion
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Pain, Postoperative
Association of Preoperative Pain With Moderate to Severe Acute Pain After Laparoscopic Cholecystectomy.
Despite advancement in perioperative pain management, more than half of the patients still report moderate-severe pain after surgery.
- Trial name
- NCT05543668
- Where
- Nepal
- Volunteers
- 195 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Opioid Use, Postoperative Pain
Comparison of Postoperative Analgesia Methods in Elective Cesarean Section Surgeries
Since many intravenous anesthetic agents administered to the mother can cross the placental barrier and cause fetal side effects, multimodal analgesia strategies with peripheral nerve blocks are preffered with greater safety in…
- Trial name
- NCT06425718
- Testing
- Postoperative Pain Management Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Arthroplasty, Replacement, Hip
Multimodal Analgesic Regimen for Total Hip Arthroplasty: An Initiative to Minimize Postoperative Opioid Use
This study examines whether patients undergoing total hip replacement surgery can manage their pain effectively while using fewer opioid pain medications. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07672808
- Testing
- Standard Multimodal Analgesic Regimen with Opioid Prescription, Opioid-Reduced Multimodal Analgesic Regimen with Printed Prescription
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
TAP Block, Cholecystectomy, Laparoscopic
Does the Transversus Abdominis Plane(TAP) Block Effectively Manage Pain After Laparoscopic Cholecystectomy?
The study is about managing pain after laparoscopic gallbladder surgery. Pain after surgery is very common and can affect recovery, delay normal activities, and increase the length of hospital stay.
- Trial name
- NCT07800624
- Testing
- TAP Block
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Surgical Site Infection, Sternal Wound Infection
Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation.
- Trial name
- SWAG (NCT04592328)
- Testing
- Bacterial cultures taken during surgery.
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative
Remote Assessment of Pain and Recovery Quality After Surgery Using a Digital Form: A Pilot Study
After surgery, doctors need to know how patients are doing, especially in the first hours after they leave the recovery room. This can be hard to track once patients go to a regular hospital room, and some symptoms - like pain or…
- Conditions
- Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative, Postoperative Nausea and Vomiting, Recovery of Function (G11.427.698.620)
- Trial name
- NCT07794267
- Testing
- Digital web-based postoperative follow-up form
- Where
- Brazil
- Volunteers
- 213 people
- Sponsor
- Hospital de Base
Epidural Anesthesia, Catheterisation
Epidural Catheter Placement Techniques by Anesthesia Residents: Success and Complications
This prospective observational study aims to evaluate the impact of epidural catheter placement techniques - loss of resistance (LOR) and hanging drop (HD) - on first-attempt success rates and procedural complications among…
- Conditions
- Epidural Anesthesia, Catheterisation, Education, Postoperative Pain
- Trial name
- EPİ-TECH (NCT07573007)
- Testing
- epidural catheter placement
- Where
- Turkey (Türkiye)
- Volunteers
- 440 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Postoperative Delirium, Elderly Patients
The Effects of Subanesthetic S-ketamine on Postoperative Delirium and Cognitive Function in the Elderly Undergoing Non-cardiac Thoracic Surgery
Postoperative delirium (POD) is a common and distressing complication after thoracic surgery. S-ketamine has neuroprotective properties as a dissociative anesthetic.
- Trial name
- SKED (NCT05242692)
- Testing
- S-ketamine, Dexmedetomidine
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Urinary Tract Infection
Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
This is a study of patients undergoing gynecologic surgery who require post-operative catheterization to determine if prophylactic antibiotic treatment decreases the risk of post-operative urinary tract infection in these…
- Trial name
- STOPP UTI (NCT01450800)
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Duke University
Pain, Postoperative
Postoperative Analgesic Efficacy of Adjuvant Quadratus Lumborum Block in Open Inguinal Hernia Surgery
Evaluation of Postoperative Analgesic Efficacy of Adjuvant Use in Quadratus Lumborum Blocks
- Trial name
- NCT06664164
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, ANTERİOR QUADRATUS LUMBORUM BLOCK WİTH ADJUVANT
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Cohort Studies
The Relationship Between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients
This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the the relationship between Preoperative Anxiety and Postoperative Delirium in Elderly Chinese Patients: a…
- Trial name
- NCT06861764
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Surgical Site Infection, Obesity
SUpPress SSI - Single Use Negative Pressure Wound Therapy (NPWT) to Reduce Surgical Site Infections
Our goal is to provide data that will give surgeons and hospitals clear recommendations on the use of NPWT for Cesarean section, abdominal hysterectomy and colon surgeries in patients with diabetes and/or obesity.
- Conditions
- Surgical Site Infection, Obesity, Diabetes, Cesarean Section Complications
- Trial name
- SUpPressSSI (NCT03816293)
- Testing
- Negative Pressure Wound Therapy
- Where
- 5 sites in United States
- Volunteers
- 3,680 people
- Sponsor
- University of Illinois Chicago
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