Clinical trials: Post Operative Fluid Management
Postoperative Complications
Intraoperative Fluid Management Guided by Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries
This study investigates the role of respiratory variation in the internal jugular vein as a tool for intraoperative fluid management during abdominal surgeries under general anesthesia.
- Trial name
- NCT07041021
- Testing
- Respiratory variation of the Internal Jugular Vein (IJV)
- Where
- 2 sites in Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Liver Transplantation (LT), End-stage Liver Disease (ESLD)
Restrictive Fluid Management In Liver Transplantation (REFIL)
The goal of the REFIL-2 study is to evaluate the effectiveness of a low splanchnic blood volume restrictive fluid management strategy (a strategy that involves limiting fluid administration and prioritizing the use of medications…
- Trial name
- REFIL-2 (NCT07695363)
- Testing
- Low splanchnic blood volume restrictive fluid management strategy, Phlebotomy, Optimized cardiac output liberal fluid management strategy
- Where
- 4 sites in Canada
- Volunteers
- 866 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Other Complications of Esophagostomy
Outcome Study of Restrictive vs. Liberal Intraoperative Fluid Management Guided by PPV in Esophagectomy
The purpose of this study is to determine whether intraoperative restrictive fluid management guided by pulse pressure variation produces a better effect on the postoperative lung function, kidney function, inflammatory response…
- Trial name
- PPV (NCT01933451)
- Testing
- Intraoperative fluid therapy
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- National Taiwan University Hospital
Postoperative Nausea and Vomiting
Dextrose Containing Fluid and the Postoperative Nausea and Vomiting in the Gynecologic Laparoscopic Surgery
The investigators tested the hypothesis that administration of intravenous dextrose as a maintenance fluid in gynecologic laparoscopic surgery would reduce the incidence and severity of postoperative nausea and vomiting (PONV)…
- Trial name
- NCT03139383
- Testing
- dextrose solution, saline solution
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Enhanced Recovery After Surgery, Anesthesia
Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery
Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our…
- Conditions
- Enhanced Recovery After Surgery, Anesthesia, Surgery-Complications, Colorectal
- Trial name
- NCT06065696
- Testing
- Early mobilization, No early mobilization
- Where
- Indonesia
- Volunteers
- 343 people
- Sponsor
- Universitas Indonesia
Renal Transplant, DGF
Does Early Postoperative Fluid Management Affect Functional Delayed Graft Function After Living Donor Kidney Transplantation?
Fluid management in renal transplantation is of critical importance for optimizing graft function and minimizing complications such as delayed graft function (DGF) and acute kidney injury (AKI).
- Trial name
- NCT07392996
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Ankara University
Venous Congestion, Postoperative Care
Portal and Splenic Venous Pulsatility in Postoperative Critically Ill Patients
Venous congestion is common in critically ill postoperative patients and may be associated with adverse outcomes. Doppler ultrasound assessment of venous flow patterns, including portal venous pulsatility, is increasingly used to…
- Trial name
- PULSE-ICU (NCT07826481)
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Surgery--Complications
Goal-directed Therapy in Neurosurgery.
The purpose of the study is to assess feasibility of future large randomised controled study aimed on assessment of effect of goal-directed therapy on incidence of complications in neurosurgery compared to standard care.
- Trial name
- NCT04754295
- Testing
- Goal-Directed Therapy, STANDARD
- Where
- Czechia
- Volunteers
- 34 people
- Sponsor
- Brno University Hospital
Microcirculatory Diffusion, Microcirculatory Convection Capacity
Association of Microcirculation, Vexus Score and Femoral Vein Doppler in Patients on the ICU After Non-emergency Cardiac Surgery
The aim of the VeMic study is to explore if venous congestion is linked with microcirculatory impairment in elective cardiac surgery patients in the postoperative ICU stay.
- Conditions
- Microcirculatory Diffusion, Microcirculatory Convection Capacity, Venous Congestion, Postoperative Cardiac Surgery
- Trial name
- VeMic (NCT07052461)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Major Abdominal Surgery, Perioperative Haemodynamic Monitoring
Continuous Central Venous Oxygen Saturation Assisted Intraoperative Hemodynamic Management
Patients who are scheduled for: elective oesophageal tumour resection, total gastrectomy, pancreas resection, major vascular, total cystectomy will be recruited.To investigate effects of central venous pressure (CVP) and central…
- Conditions
- Major Abdominal Surgery, Perioperative Haemodynamic Monitoring, Perioperative Fluid Management, Perioperative Vasopressor Requirement
- Trial name
- NCT02337010
- Testing
- CeVOX, CVP, Fluid bolus
- Where
- Hungary
- Volunteers
- 79 people
- Sponsor
- Domonkos Trásy
Cerebrospinal Fluid Leak
Perioperative CSF Leak Management - an Opinion Study
Cerebrospinal fluid (CSF) leak is a rare condition. When it involves the ventral skull base, a surgical closure may be achieved using endoscopic skull base surgery techniques.
- Trial name
- NCT04124523
- Where
- France
- Volunteers
- 153 people
- Sponsor
- University Hospital, Montpellier
Remimazolam, Propofol
Remimazolam on the Incidence of Postoperative Acute Kidney Injury
We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the…
- Conditions
- Remimazolam, Propofol, Acute Kidney Injury, Hemodynamic Stability
- Trial name
- NCT07674719
- Testing
- Remimazolam (Byfavo), propofol
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Complications
Stroke Volume Variation vs Central Venous Pressure Guidance Fluid Management in Endovascular Aortic Repair
Hypothesis: Fluid management guided by stroke volume variation (SVV), compared with central venous pressure (CVP), guidance results in better clinical outcomes.
- Trial name
- NCT03218540
- Testing
- Fluid management protocol
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Khon Kaen University
Surgery Complications
Effects of GDHT (Goal Directed Hemodynamic Therapy) Using a Non-invasive Hemodynamic Monitoring in Elective Neurosurgery
This study aims to assess the safety and efficacy of GDHT using the non-invasive Starling™ SV System in elective neurosurgery. The tested group of patients (n=70) will be compared with a control group (n=70), where hemodynamic…
- Trial name
- NCHGDT (NCT07101991)
- Testing
- Standard monitoring, Goal-Directed Therapy
- Where
- Czechia
- Volunteers
- 140 people
- Sponsor
- Brno University Hospital
Peri-operative Fluid Management
Response to Varying the Rate of Administration of a Fluid Challenge
Administration of intravenous fluids is a key step in the management of the post-operative patient. Fluid management has been identified as one area that can affect rates of post-operative complications and outcomes.
- Trial name
- NCT03300323
- Testing
- IV fluid challenge administration
- Volunteers
- 40 people
- Sponsor
- St George's Healthcare NHS Trust
Coronary Artery Disease, Anemia
Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of MUF
It is hypothesized that on-line modified ultrafiltration (MUFF) post-cardiopulmonary bypass will result in improved patient outcomes over the 12-hour post-operative period as compared to control and off-line MUFF.
- Trial name
- MUF (NCT01864395)
- Testing
- Centrifugation Method, Online MUF, Offline MUF
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Saskatchewan
Postoperative Complication
Goal Directed Fluid Management Based on Non-invasive Monitoring
The purpose of this study is to evaluate whether goal directed fluid management using respiratory variations in the oxygen saturation by pulse oximetry (SpO2) waveform has potential to decrease postoperative complications and…
- Trial name
- NCT01883752
- Testing
- Goal-directed Therapy group
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- University of California, Irvine
Cardiac Arrest, Post Cardiac Arrest Syndrome
Lung-cOnservative Liquid VEntilation for the Induction of Ultra-Rapid COOLing After Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) affects over 356,000 individuals annually in the United States, with fewer than 10% surviving to hospital discharge, mirroring statistics from Europe.
- Trial name
- OverCool (NCT06798818)
- Testing
- Ultra-rapid therapeutic hypothermia induction by total liquid ventilation
- Where
- France
- Volunteers
- 24 people
- Sponsor
- ORIXHA
Acute Lung Injury (ALI), Acure Respiratory Distress Syndrome (ARDS)
Effect of Intraoperative Fluid Restriction on Postoperative Outcomes in Video-assisted Thoracic Surgery (VATS)
The objective of this study is to compare the effects of two intraoperative fluid regimens - restrictive versus liberal (standard)- on postoperative outcomes (e.g.
- Conditions
- Acute Lung Injury (ALI), Acure Respiratory Distress Syndrome (ARDS), Sepsis
- Trial name
- NCT00854386
- Testing
- liberal fluid administration, restrictive fluid administration
- Where
- 2 sites in Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Pain, Postoperative
Patient Controlled Administration of Liquid Acetaminophen
This is a proof of concept pilot study investigating the feasibility and acceptability of patient controlled oral medication administration, using the commonly used and low risk medication in the hospital, oral acetaminophen.
- Trial name
- NCT06498713
- Testing
- Acetaminophen 650 mg Oral Tablet, Acetaminophen 650mg Liquid, CADD pump
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University