Clinical trials: Post Operative Nutrition, active
Morbid Obesity
Bougie Sleeve Trial
Staple-line leak is the most frequent and incapacitating complication after laparoscopic sleeve gastrectomy (LSG). The aim of this prospective randomized trial is to compare the staple-line leak rate after LSG according to the…
- Trial name
- BOUST (NCT02937649)
- Testing
- Laparoscopic sleeve gastrectomy using 48-Fr bougie, Laparoscopic sleeve gastrectomy using standard care bougie
- Where
- 12 sites in France
- Volunteers
- 1,658 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Site Infections, Depression
Incidence of Depression and Its Complications After Surgical Site Infection - ISODEP.
Surgical-site infection (SSI) in orthopedic surgery is a serious and frequent complication with many consequences on the patient's quality of life.
- Conditions
- Surgical Site Infections, Depression, Malnutrition
- Trial name
- ISODEP (NCT07125196)
- Testing
- Data collection and self-administered questionnaire
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux
Parenteral Nutrition, Nutritional Status
Effects of Preoperative Parenteral Nutrition With Omega-3 Fish Oil Lipid Emulsion on Postoperative Outcomes in Patients Undergoing Major Abdominal Surgery
The goal of this study is to explore if preoperative ω-3 fish oil lipid emulsion parenteral nutrition (PN) can improve postoperative outcomes in patients undergoing major abdominal surgery.
- Conditions
- Parenteral Nutrition, Nutritional Status, Major Abdominal Surgery
- Trial name
- NCT07878468
- Testing
- ω-3 fish oil lipid emulsion, Conventional lipid without ω-3 fish oil
- Where
- 7 sites in China
- Volunteers
- 158 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Pulpitis - Irreversible, Vitamin D Deficiency
Effect of Vitamin D on Postoperative Pain in Symptomatic Irreversible Pulpitis
Vitamin D deficiency (VDD) is a prevalent global health concern that has been linked to altered pain perception through its effects on inflammatory pathways, nociceptor activity, and neurotrophic signaling.
- Trial name
- NCT07579637
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Future University in Egypt
Tonsillectomy, Bleeding
Postoperative Care After Tonsillectomy
Tonsillectomy is one of the most common surgical procedures performed on both pediatric and adult patients; it is frequently associated with significant postoperative pain, difficulty swallowing, and the risk of complications…
- Conditions
- Tonsillectomy, Bleeding, Nutrition, Healing
- Trial name
- ARAP (NCT07792057)
- Testing
- Nutrition and Hydration
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- Hospital Felicio Rocho
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
Obesity, Postoperative Bariatric Surgery
Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery
This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia…
- Conditions
- Obesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy
- Trial name
- NCT06994780
- Testing
- dynamic compliance guided PEEP titration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Postoperative Nausea and Vomiting, Postoperative Pain
Postoperative Nausea, Vomiting and Pain After Bariatric Surgery - a National Registry Study
Around 4,000-5,000 bariatric (weight-loss) operations are performed in Sweden every year. Nausea, vomiting and pain are common immediately after these operations, cause considerable suffering and increase the intensity and length…
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Obesity, Morbid, Bariatric Surgery
- Trial name
- BAROSPOR (NCT07797374)
- Where
- 2 sites in Sweden
- Volunteers
- 30,000 people
- Sponsor
- Umeå University
Obesity, Postoperative Gastrointestinal Dysfunction
Effect of TAP Block on GI Function After Sleeve Gastrectomy Using PRO-diGI Scale and Perlas Score
This prospective clinical study aims to evaluate the effect of Transversus Abdominis Plane (TAP) block on postoperative gastrointestinal function in patients undergoing laparoscopic sleeve gastrectomy.
- Trial name
- TAP (NCT07168538)
- Testing
- TAP Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Perioeprative Muscle Loss
BCAA in Patients Undergoing Gastric Cancer Surgery
Older patients undergoing gastric cancer resection, at higher risk due to insufficient preoperative muscle mass, are more susceptible to SRML under surgical stress.
- Trial name
- NCT06340399
- Testing
- BCAA, patient not administered BCAA
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Sternal Wound Complications, Obesity (Body Mass Index >30 kg/m2)
Sternal Closure in High-BMI Patients: Cable vs Wire
This retrospective study compares two sternal closure techniques-standard stainless-steel wires and rigid cable systems-in adult patients with a body mass index (BMI) ≥30 who underwent open-heart surgery between January 1, 2020…
- Conditions
- Sternal Wound Complications, Obesity (Body Mass Index >30 kg/m2), Median Sternotomy, Cardiac Surgery
- Trial name
- NCT07097272
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Samsun University
Severe Obesity, Morbid Obesity Requiring Bariatric Surgery
Early Discharge With Hospital-at-Home After Bariatric Surgery and Economic Evaluation.
Bariatric surgery is the most effective treatment for severe obesity and its associated diseases. Advances in surgical techniques, enhanced recovery protocols, and multimodal perioperative care have made earlier hospital…
- Trial name
- BEHOME (NCT07782281)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Corporacion Parc Tauli
Obesity &Amp; Overweight
The Impact of Probiotics on Bariatric Treatment Outcomes
The planned study aims to assess whether probiotics improve the quality of life in patients during the early postoperative period following sleeve gastrectomy, and whether they influence the absorption of micro- and…
- Trial name
- PROBE (NCT07258732)
- Testing
- Probiotic, Diet
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Short Bowel Syndrome
Efficacy and Safety of PJ009 in Patients With Short Bowel Syndrome Requiring Parenteral Nutrition
The main aim of this clinical trial is to assess the efficacy and safety of PJ009 in patients aged ≥14 with short bowel syndrome (SBS) requiring parenteral nutrition.
- Trial name
- NCT06512584
- Testing
- PJ009
- Where
- 8 sites in China
- Volunteers
- 72 people
- Sponsor
- Chongqing Peg-Bio Biopharm Co., Ltd.
Pain Management, Overweight , Obesity
Safety and Analgesic Efficacy of the Biased μ-Opioid Receptor Agonist Tegileridine for Post-Operative Analgesia in Patients Undergoing Bariatric Surgery
This single-center, stratified randomized double-blind trial tests tegileridine, a new pain drug, for pain relief after weight-loss surgery. Researchers will compare tegileridine with standard opioid pain medicine.
- Conditions
- Pain Management, Overweight , Obesity, Respiration; Sleep Disorder
- Trial name
- NCT07844512
- Testing
- Tegileridine (tegileridine fumarate injection, IV), Sufentanil
- Volunteers
- 148 people
- Sponsor
- The First Hospital of Jilin University
Obesity
Identification of Factors Predictive of the Efficacy of Endoscopic Endoscopic Sleeve Gastroplasty
Endoscopic sleeve gastroplasty and bypass are currently available for weight loss in obese patients who have failed nutritional management. Despite very low risks, these techniques remain invasive.
- Trial name
- PREDISLEGE (NCT06153056)
- Testing
- Bloed-, ontlasting- en speekselmonsters
- Where
- France
- Volunteers
- 205 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris