Clinical trials: Post Operative Pain, Chronic
Erector Spinae Plane Block, Pain Control
Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
Interfascial plane blocks have been developed for analgesia, among which the erector spinae plane (ESP) has gained popularity. The ESP block has been hypothesized to provide truncal analgesia by spread of local anesthetic into…
- Conditions
- Erector Spinae Plane Block, Pain Control, Post-Operative Pain, Chronic
- Trial name
- NCT04995497
- Testing
- Intravenous Administration of Lidocaine Post Cardiac Surgery, Administration of Lidocaine Post Cardiac Surgery via ESP Catheter
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Archit Sharma
Chronic Pain, Failed Back Surgery Syndrome
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
Doctors sometimes treat chronic pain with devices that send mild electrical currents into the spinal cord. This type of treatment is referred to as neurostimulation.
- Conditions
- Chronic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes, Neuropathic Pain
- Trial name
- NCT04732325
- Testing
- Spinal cord stimulation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Michigan
Chronic Rhinosinusitis
Microcurrent Device (TIVIC Health)
The purpose of this study is to investigate whether daily use of a microcurrent neuromodulation device, which applies a small current of electricity to the forehead and maxillary region, will decrease the pain experienced by…
- Trial name
- NCT05198518
- Testing
- Microcurrent TENS device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Ocular Pain
Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)
The study was designed to demonstrate the safety and efficacy of two dose concentrations of SAF312 eye drops (5 mg/mL and 15 mg/mL) in subjects with CICP persisting at least for 4 months after refractive or cataract surgery and…
- Trial name
- NCT04630158
- Testing
- SAF312
- Where
- 28 sites in United States, Japan and 1 more
- Volunteers
- 153 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Pain, Pain, Intractable
An Implantable Spinal Cord Stimulation Pain Management System
There are many treatment options available for the management of chronic pain . Some include, but are not limited to, over-the-counter medications, Non-Steroidal Anti-Inflammatory Drugs, Physical Therapy, Transcutaneous…
- Conditions
- Chronic Pain, Pain, Intractable, Pain, Back Pain
- Trial name
- NCT00205855
- Testing
- Precision SCS
- Where
- 9 sites in United States
- Volunteers
- 65 people
- Sponsor
- Boston Scientific Corporation
Pain, Postoperative, Hip Pain Chronic
PENG Block Versus LP Block for THA Postop Pain
The purpose of this randomized, double blinded, prospective study is to compare the postoperative analgesia provided by the PENG block to that provided by the LPB for patients undergoing primary anterior approach THA.
- Trial name
- NCT05261009
- Testing
- Peri-capsular Nerve Group (PENG), Lumbar Plexus Block (LPB)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Postoperative, Chronic Postoperative Pain
Analgesia in Laparoscopic Cholecystectomy
The investigators hypothesis is that perioperative infusion of 0.75 ropivacaine in patients undergoing laparoscopic cholecystectomy may modify the intensity of postoperative pain or the analgesic consumption during the first 24…
- Trial name
- NCT01388946
- Testing
- Ropivacaine 0.75, Normal saline
- Where
- 2 sites in Greece
- Volunteers
- 110 people
- Sponsor
- University of Athens
Surgery
Lidocaine and Prevention of Chronic Pain
The study seeks to investigate a safe and inexpensive strategy to reduce persistent post-surgical pain that can affect up to 60% of patients undergoing surgical procedures.
- Trial name
- NCT01619852
- Testing
- Group L (lidocaine)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Northwestern University
Chronic Sinusitis
Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery
The purpose of this study is to assess the use of IV acetaminophen (Ofirmev) as a and safe and efficacious agent in reducing post-operative pain; we hypothesize that its use will reduce post-operative pain when compared to a…
- Trial name
- IVAPAP (NCT01608308)
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Postoperative
Effect of Ketamine on Analgesia Post-Cardiac Surgery
Randomized, controlled, double-blind pilot study evaluating the effect of an intraoperative infusion of intravenous Ketamine on the quantity of opioid consumed postoperatively in coronary artery bypass surgery patients receiving…
- Trial name
- NCT02925858
- Testing
- Normal Saline Flush, 0.9% Injectable Solution_#1, Ketamine Hydrochloride
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Jewish General Hospital
Inguinal Hernia, Postoperative Pain
Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal hernia repair is one of the most frequently performed operations in young men. Persistent pain after inguinal surgery represents a significant cause of disability, occurring in between 15%-35% of cases.
- Trial name
- NCT00825344
- Testing
- Etanercept, Saline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Juvenile; Scoliosis, Scoliosis Idiopathic
Digital Health Psychosocial Intervention for Adolescent Spine Surgery Preparation and Recovery
This is a randomized controlled trial to test effectiveness of the SurgeryPal intervention vs. education control to improve acute and chronic pain and health outcomes in youth undergoing major musculoskeletal surgery.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgeryPal (NCT04637802)
- Testing
- CBT (SurgeryPal), Education
- Where
- United States
- Volunteers
- 433 people
- Sponsor
- Seattle Children's Hospital
Pain, Intractable
OPTIONS Spinal Cord Stimulation Programming Parameters
The purpose of this study is to evaluate programming options in spinal cord stimulation for the management of chronic, intractable pain of the trunk and limbs.
- Trial name
- NCT02503787
- Testing
- Spinal Cord Stimulation (SCS)
- Where
- 11 sites in United States
- Volunteers
- 64 people
- Sponsor
- MedtronicNeuro
Chronic Post-Surgical Pain
Pre-op Cognitive Behavior Therapy to Decrease Chronic Post-Surgical Pain in TKA
A significant number of patients develop chronic post-surgical pain (CPSP) following knee replacement surgery. Proposed is the testing of a novel computer-assisted behavioral intervention integrating motivational interviewing in…
- Trial name
- NCT04814992
- Testing
- Computer-Assisted Preoperative CBT Intervention (PAINTrainer)
- Where
- 4 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Post-Amputation Pain, Phantom Limb Pain
Electrical Nerve Block for Amputation Pain
The purpose of the clinical trial is to learn whether electrical nerve block via the Altius System is a safe and effective treatment for patients with post-amputation pain.
- Conditions
- Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain, Stump Pain
- Trial name
- NCT02221934
- Testing
- Altius
- Where
- 22 sites in United States
- Volunteers
- 607 people
- Sponsor
- Neuros Medical, Inc.
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05045625
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albany Medical College
Laminectomy, Post-laminectomy Syndrome
Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Traditionally, pain relief through spinal cord stimulation has been associated with the appearance of paresthesia in the affected area.
- Conditions
- Laminectomy, Post-laminectomy Syndrome, Spinal Cord Syndrome, Failed Back Surgery Syndrome
- Trial name
- NCT03702010
- Testing
- spinal cord stimulation conventional, spinal cord stimulation experimental
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Chronic Post Surgical Pain
A Post Market Study to Assess the Spinal Modulation Dorsal Root Ganglion Stimulator System in Chronic Post Surgical Pain
20-SMI-2013 is a post market, observational, questionnaire based study to assess the effectiveness of the commercially available Axium neurostimulator in the management of chronic post surgical pain
- Trial name
- NCT02335229
- Testing
- Axium DRG Neurostimulator
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Abbott Medical Devices
Phantom Limb Pain, Postoperative Pain
Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Limb loss is frequently associated with postamputation pain that can be challenging to treat and often involves opioids. Advances in the field of neuromodulation has led to development of an intentionally reversible percutaneous…
- Conditions
- Phantom Limb Pain, Postoperative Pain, Neuroma, Acute Pain
- Trial name
- NCT03484429
- Testing
- Peripheral nerve stimulation, Standard Medical Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Persistent Postsurgical Pain
Risk Factors and Mechanisms for Persistent Postsurgical Pain After Total Knee Replacement
Osteoarthritis (OA) is the single most common cause of disability in mid and late life. About 27 million people in the United States suffer from this incurable process and 10 million have OA of the knee.
- Trial name
- PPP-TKA (NCT01320150)
- Where
- United States
- Volunteers
- 311 people
- Sponsor
- Rush University Medical Center