Clinical trials: Post Operative Pain
Chronic Post-surgical Pain
Duloxetine to Prevent Chronic Postsurgical Pain After Inguinal Hernia Repair in Patients at High Risk
The clinical trial will be conducted in 14 Spanish hospitals. It is estimated, based on our previous studies, that 2855 patients scheduled for elective inguinal hernia surgery will have to be assessed to detect patients with ≥…
- Trial name
- GENDOLCAT3 (NCT06606067)
- Testing
- Duloxetine
- Where
- Spain
- Volunteers
- 294 people
- Sponsor
- Parc de Salut Mar
Postoperative Pain
The Effect of Quran of Post Operative Pain
Postoperative pain management is crucial for surgical patients. Management of postoperative pain entails reducing painful symptoms, improving the quality of recovery and resuming normal daily living activities.
- Trial name
- NCT02589834
- Testing
- Quran group
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Assiut University
Postsurgical Pain
Study of CA-008 (Vocacapsaicin) in Total Knee Arthroplasty
This is a two-part, Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study of CA-008 (vocacapsaicin) vs. placebo injected/instilled during an elective TKA.
- Trial name
- NCT03731364
- Testing
- CA-008
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Concentric Analgesics
Pain
Etoricoxib With Flavoxate for Reducing Morphine Requirement After Transurethral Prostatectomy (TURP)
The purpose of this study is to determine whether etoricoxib, flavoxate, both are effective in the treatment postoperative pain after TURP.
- Trial name
- NCT00440739
- Testing
- etoricoxib, flavoxate, etoricoxib, flavoxate
- Where
- Thailand
- Volunteers
- 128 people
- Sponsor
- Mahidol University
Adenoid Hypertrophy
A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients
This proposed study will assess analgesic efficacy of a multi-modal, non-opioid analgesic regimen for providing surgical analgesia in pediatric patients undergoing adenoidectomy and to assess recovery characteristics in the…
- Trial name
- NCT03714919
- Testing
- Dextromethorphan, Acetaminophen, Dexmedetomidine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Arlyne Thung
Chronic Pain Following Surgical Procedure for Cancer
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group)…
- Trial name
- NCT04700592
- Testing
- Gabapentin versus Ketamine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Pain and Cognitive Dysfunction Management in Hip Surgery
Prospective Comparative Study Between Ultrasound-guided Quadratus Lumborum Block Versus Fascia Iliaca Compartment Block for Postoperative Pain and Cognitive Dysfunction Management in Patient Undergoing Hip Surgery
Hip fractures are more common in older people due to osteoporosis. It is estimated that around six million patients worldwide will suffer hip fractures annually by 2050 as the population ages [1].
- Trial name
- NCT06407544
- Testing
- peripheral nerve block, PCA device as rescue medication with IV morphine 1mg if VAS more than 4
- Volunteers
- 60 people
- Sponsor
- Sohag University
Crown Lengthening, Pain Postoperative
Aesthetic Crown Lengthening: Laser Impact on Pain Perception and Perceptions on Self-esteem and Quality of Life
Gummy smile is a condition that promotes a disharmonious smile, altering confidence and decreasing self-esteem of many patients. Luckily, this problem in most cases is easily solved by aesthetic crown lengthening surgery.
- Conditions
- Crown Lengthening, Pain Postoperative, Self Concept
- Trial name
- NCT06830434
- Testing
- Crown lengthening surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain
Ultrasound Guided TAP Block for Postoperative Analgesia After Abdominal Surgery.
Transversus abdominis plane (TAP) block is a novel type of peripheral nerve block that involves innervations of the anterolateral abdominal wall derived from T6-L1.It provides adequate post-operative pain relieve following the…
- Trial name
- TAB (NCT02976597)
- Testing
- Bupivacaine 0.25% 20ml on each side Sonar guided TAB, Morphine 10mg, Morphine 15mg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Postoperative Pain, Preoperative Sleep Quality
The Effect of Sleep Quality Before Breast Surgery on Postoperative Pain
This study aimed to investigate the relationship between preoperative sleep quality and postoperative pain in patients undergoing mastectomy or breast-conserving surgery under general anesthesia.
- Trial name
- NCT07892924
- Testing
- Sleep Quality and Postoperative Pain Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Sports Physical Therapy
PNF and BFR Affect on Pain, ROM & Functional Outcome in Post-op ACL
A randomized controlled trial investigated the effects of Hold Relax Technique (HRT) with and without Blood Flow Restriction (BFR) on pain, range of motion (ROM), and functional disability in patients with post-operative ACL…
- Trial name
- NCT06943079
- Testing
- Effect of Hold Relax technique with Blood Flow Restriction technique on functional outcome, Effect of Hold Relax technique without Blood Flow Restriction technique on functional outcomes
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Postoperative Pain, Topical Anaesthesia
Topical Lidocaine After Arthroscopy on Knee
More than half of the patients suffer from intensive pain 1-2 days after arthroscopy in the knee. Walking function and physical activities are affected by this intensive pain although local anaesthetic is given in the joint and…
- Trial name
- NCT02460627
- Testing
- Lidocaine adhesive tape, Adhesive tape
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Postoperative Pain
A Phase 2 Study to Evaluate Pregabalin and Acetaminophen Compared to Acetaminophen and Placebo in Subjects Undergoing Bunionectomy
A Phase 2, Randomized, Double-Blind, Placebo- and Comparator-Controlled Trial to Evaluate the Safety and Efficacy of Combination Pregabalin and Acetaminophen Compared to Acetaminophen and Placebo in Subjects Undergoing…
- Trial name
- NCT04495283
- Testing
- Pregabalin, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Pulp Necroses
Laser Activated Irrigation Versus Passive Ultrasonic Irrigation
assessment of bacterial reduction and post-operative pain following Laser activated irrigation using sodium hypochlorite and a 980 nm diode laser device as an adjunct to conventional root canal treatment, and comparing it with…
- Trial name
- NCT04035083
- Testing
- Laser activated irrigation, Passive ultrasonic irrigation
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgery, Pain Postoperative
Efficacy of Rectal Sheath Analgesia After Midline Laparotomy
Midline laparotomy is commonly used in emergency and elective cancer surgery and patients need effective and safe pain treatment after this type of surgery.
- Trial name
- Rektus-puu (NCT02869841)
- Testing
- Levobupivacaine continuous infusion, levobupivacaine bolus dosing, single bolus of levobupivacaine
- Where
- Finland
- Volunteers
- 57 people
- Sponsor
- Kuopio University Hospital
Postoperative Pain
Predictors of Postoperative Pain
This is a retrospective chart review using TriHealth Electronic Privacy Identification Center (EPIC) and previously developed databases for TriHealth Institutional Review Board (IRB) approved research studies within the Division…
- Trial name
- NCT02996994
- Volunteers
- 364 people
- Sponsor
- TriHealth Inc.
Knee Osteoarthritis
Ambulatory Continuous Adductor Canal Block to Facilitate Same Day Discharge Following Total Knee Arthroplasty: A Pilot Study
Patients scheduled to undergo total knee arthroplasty will receive motor sparing knee blocks with continuous adductor canal block along with multimodal analgesia started pre-operatively and continued into the postoperative…
- Trial name
- NCT02228759
- Testing
- Adductor canal block
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Narcotic Use, Renal Transplant Donor of Left Kidney
Postoperative Pain Protocol Limiting Narcotics for Laparoscopic Hand-assisted Donor Nephrectomy
Kidney donors represent healthy patients and their anticipated postoperative course should be uncomplicated and brief. This study looks to optimize the perioperative pain regimen of laparoscopic donor nephrectomy patients by…
- Trial name
- NCT06458842
- Testing
- Ketamine
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stony Brook University