Clinical trials: Post Operative Pain Control, open to volunteers
Pain, Postoperative
Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery
Participants who have a surgical procedure called Posterior Cervical (neck) Spine Surgery will normally need pain medication to relieve post operative pain. This usually includes opioid medications.
- Trial name
- NCT06570577
- Testing
- Inter-semispinalis Plane Block, Opioids
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Postoperative Pain Control, Coronary Artery Disease
Serratus Anterior Plane Block for Recovery After Minimally Invasive CABG
Coronary artery bypass surgery is an important treatment method for severe coronary heart disease. Among them, minimally invasive bypass surgery, although having less trauma, requires a small incision on the left chest.
- Trial name
- NCT07877532
- Testing
- Ultrasound-guided Serratus Anterior Plane Block with Ropivacaine, Ultrasound-guided Serratus Anterior Plane Block with Normal Saline
- Volunteers
- 168 people
- Sponsor
- Chinese PLA General Hospital
Fractures, Closed, Humeral Fractures
Regional Blocks for Lateral Condyle Fractures
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning.
- Conditions
- Fractures, Closed, Humeral Fractures, Pain
- Trial name
- NCT03796572
- Testing
- Ropivacaine, Puncture Wound and Dressing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Vasectomy, NSAIDs
Post-Vasectomy Pain Study
This is a prospective four-armed unblinded randomized controlled trial to assess four different potential post-operative treatment options for men who undergo a vasectomy.
- Conditions
- Vasectomy, NSAIDs, Post-operative Care
- Trial name
- NCT07824258
- Testing
- Acetaminophen, ibuprofen, oxycodone
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Post Operative Pain
A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves
This is a retrospective and prospective, multicenter, observational patient registry to record outcomes from patients undergoing cryoablation of the intercostal nerves (cryoanalgesia) for post-operative pain management.
- Trial name
- REDUCE (NCT05110989)
- Testing
- AtriCure Cryo Nerve Block (cryoNB) Device Family
- Where
- 11 sites in United States, Austria and 3 more
- Volunteers
- 5,000 people
- Sponsor
- AtriCure, Inc.
Acute Pain, Postoperative Pain
Study of QL Analgesic Response and Extent
A total of 14-18 healthy volunteers will be included. There will be three different procedure days, separated by at least one week. On each visit, the subjects will receive a QL block, according to the randomization process.
- Conditions
- Acute Pain, Postoperative Pain, Regional Anesthesia Block
- Trial name
- SQUARE (NCT07566312)
- Testing
- Quadratus Lumborum with 1.5% Lidocaine
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Hemorrhoids
Ketamine for Post-operative Analgesia in Hemorrhoidectomy
This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids.
- Trial name
- NCT04248205
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Post-operative Pain, Vital Pulp Therapy
Compare the Impact of Sodium Hypochlorite and Saline Irrigation Protocols With and Without Cryotherapy on Post-operative Pain Following Pulpotomy in Permanent Mandibular Molar Teeth.
The aim of the present study will compare the impact of sodium hypochlorite and saline irrigation protocols with and without cryotherapy on post-operative pain following pulpotomy in permanent mandibular molar teeth.Will the use…
- Trial name
- NaOCl/VPT/MTA (NCT07764666)
- Testing
- VPT /pulpotomy, VPT/complete pulpotomy, vital pulp therapy /complete pulpotomy
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Abdelrahman Refaat Khalaf Ahmed
Post Operative Pain, Opioid Use
Serratus vs ESP Block for Postoperative Pain in Unilateral Breast Surgery
This prospective, randomized, assessor-blinded trial compares serratus posterior superior intercostal plane block (SPSIPB) and erector spinae plane block (ESPB) for postoperative analgesia in unilateral breast surgery.
- Trial name
- NCT07541040
- Testing
- Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Engin Çetin
Chronic Shoulder Pain
Exparel for Total Shoulder Pain
Total shoulder surgery (arthroplasty) is a widely successful method of treating shoulder arthritis. Although the goal of the procedure is pain relief, post-operative pain is unavoidable.
- Trial name
- ETSP (NCT03739021)
- Testing
- Exparel, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Post Operative Pain
Post Operative Infusion Pump Pain Study
This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period..
- Trial name
- NCT07349810
- Testing
- Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Hemorrhoids, Postoperative Pain
Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy Pain
Hemorrhoid surgery is often followed by significant pain during the first few days after the operation. Pudendal nerve block is a pain-control technique that can help reduce discomfort after surgery.
- Conditions
- Hemorrhoids, Postoperative Pain, Pudendal Nerve Block
- Trial name
- NCT07889869
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Landmark-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain
QLESP Block for Pain Control in Robotic Partial Nephrectomy
The goal of this clinical trial is to learn if an ultrasound-guided nerve block called QLESP works to reduce pain and the need for strong pain medicines after robotic kidney surgery in adults.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain, Nerve Block
- Trial name
- NCT07704970
- Testing
- ropivacaine (local infiltration), ropivacaine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Pain
Role of Alprazolam in Management of Post Endodontic Pain After Single Visit Root Canal Treatment. To Compare Mean Pain Score Between Two Group of Participants Undergoing Post Operative Pain Management After Single Visit Root Canal Treatment: NSAIDs Alone and a Combination of NSAIDs and Alprazolam.
To compare mean pain score between two group of participants undergoing post operative pain management after single visit root canal treatment: one group receiving NSAIDs alone and the other receiving a combination of NSAIDs and…
- Trial name
- NCT07275710
- Testing
- Brufen and alprazolam, Brufen
- Where
- 2 sites in Pakistan
- Volunteers
- 110 people
- Sponsor
- Armed Forces Post Graduate Medical Institute (AFPGMI), Rawalpindi
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Post Operative Pain
Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides
General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique.
- Trial name
- NCT07357233
- Testing
- Manual-less, Conventional technique
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Post Operative Analgesia
Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery
The aim of this study to compare the analgesic effects of intraarticular dexmedetomidine added to bupivacaine with those of bupivacaine alone after knee arthroscopy
- Trial name
- DEXMED (NCT06665438)
- Testing
- Bupivacaine 0.25%, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Post Operative Pain, Laparoscopic Hysterectomy
Preoperative Acetazolamide
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain.
- Conditions
- Post Operative Pain, Laparoscopic Hysterectomy, Referred Pain
- Trial name
- NCT07101250
- Testing
- Acetazolamide 500 MG Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Prisma Health-Upstate
Pain, Postoperative
Pain Management Study
This study aims to better understand the role that narcotic vs. non-narcotic multimodal pain management play in patients' pain following bariatric surgery (Laproscopic Surgery and Robotic Assisted Surgery).
- Trial name
- NCT05231460
- Testing
- Active Comparator: narcotic regimen with TAP block, Active Comparator: narcotic regimen with no TAP block, non-narcotic regimen with TAP block
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- University of Arizona