Clinical trials: Post Operative Pain Control, open to volunteers
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post Operative Pain
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by…
- Trial name
- NCT06349772
- Testing
- Zynrelef, Exparel
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Pain, Postoperative
Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial.
- Trial name
- NCT04260854
- Testing
- Bupivacaine Hydrochloride, Saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain After Photorefractive Keratectomy, VAS Will be Used to Assess Pain Postoperative
Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study
The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.
- Trial name
- NCT06752486
- Testing
- Giving post photorefractive keratectomy for pain relief
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Adenotonsillectomy, Postoperative Pain
Preoperative Celecoxib and Acetaminophen Versus Acetaminophen Alone for Pain Control After Pediatric Adenotonsillectomy
This is an open-label randomized study of approximately 500 pediatric patients (2-18 years of age, weighing more than 10 kg) undergoing adenotonsillectomy.
- Trial name
- NCT07870447
- Testing
- Celecoxib, Acetaminophen, Dexamethasone
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- NYU Langone Health
No Condition, Assessment of Healthy Volunteers
Usefulness of Intraosseous Anesthesia for Permanent Tooth Extraction Under GA in Pediatric Dental Treatment
The investigators are doing a study to see if a new way of giving local anesthesia during dental surgery can help children feel better after having a tooth removed under general anesthesia (when they are fully asleep).
- Trial name
- NCT07108439
- Testing
- Administration of intra-osseous local anesthesia before the extraction of a first permanent molar under general anesthesia
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
İnguinal Hernia, Post Operative Pain
Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- NCT07604259
- Testing
- Lateral Quadratus Lumborum Block, Transversalis Fascia Plane Block, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Surgery
Green Light for Post-Operative Wellness
This is an unblinded, parallel group randomized controlled trial to evaluate bright green light as an adjunct therapy after surgery at UPMC Shadyside.
- Trial name
- GLOW (NCT07218289)
- Testing
- Bright Green Light Therapy, Dim White Light Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rebecca E Kotcher, MD
Postoperative Pain
Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery
The goal of this study is to compare whether oral or intravenous acetaminophen works better for pain control in patients undergoing lumbar spine fusion surgery
- Trial name
- NCT07203079
- Testing
- Acetaminophen Oral Tablet, Acetaminophen infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Stanford University
Pilonidal Sinus, Wound Healing
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
This is a single-blinded, multicentre, prospective randomised controlled trial (RCT) comparing post-operative and patient-reported outcomes for patients undergoing application of negative-pressure wound therapy (NPWT) after sinus…
- Trial name
- ENVELOP (NCT06647290)
- Testing
- Negative Pressure Wound Therapy, Standard wound care
- Where
- 10 sites in Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
Rotator Cuff Tear Repair, Interscalene Blocks
Preoperative Versus Postoperative Interscalene Block in Arthroscopic Rotator Cuff Repair
This study is evaluating whether the timing of an interscalene nerve block affects pain control and recovery after arthroscopic rotator cuff repair surgery.
- Conditions
- Rotator Cuff Tear Repair, Interscalene Blocks, Rotator Cuff Tears
- Trial name
- ISB-ARCR (NCT07689448)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istinye University
Postoperative Pain, Acute
Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries.
- Trial name
- K-IVRAg (NCT05543785)
- Testing
- Ketorolac, Control
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Postoperative Pain, Cardiac Surgery
Efficacy of Serratus Posterior Superior Intercostal Plane Block on Post-operative Pain in Cardiac Surgery.
Cardiac surgery, particularly procedures involving median sternotomy, is associated with significant postoperative pain. Acute postoperative pain is severe in cardiac patients undergoing sternotomy, and pain intensity is more…
- Trial name
- NCT07175298
- Testing
- conventional opioid-based technique, SPSIPB Group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Pain, Postoperative
Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery
Participants who have a surgical procedure called Posterior Cervical (neck) Spine Surgery will normally need pain medication to relieve post operative pain. This usually includes opioid medications.
- Trial name
- NCT06570577
- Testing
- Inter-semispinalis Plane Block, Opioids
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Pain, Post-operative, Pneumoperitoneum
Does Trendelenburg Positioning During Pulmonary Recruitment Breaths Affect Post-laparoscopy Shoulder Pain
The goal of this clinical trial is to evaluate whether different positioning in the operating room during removal of laparoscopic surgical gas differs in post-surgery shoulder pain.
- Conditions
- Pain, Post-operative, Pneumoperitoneum, Urogynecologic Surgery
- Trial name
- NCT07631728
- Testing
- Pulmonary recruitment maneuver, Trendelenburg position
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankita Gupta
Post Operative Pain, Anesthesia
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
Comparison of post-operative pain after total shoulder surgery. The Principle Investigator will be comparing Exparel single shot block to Interscalene catheter
- Conditions
- Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
- Trial name
- NCT05868330
- Testing
- Interscalene Catheter, Exparel Single Shot Interscalene Block
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
Post Operative Pain
Rhomboid Intercostal Block Versus Retrolaminar Block for Postoperative Analgesia After Thoracoscopic Sympathectomy
Background: Although thoracoscopic sympathectomy is made via small incisions, it is associated with severe postoperative pain. Both Rhomboid intercostal block (RIB) and Retrolaminar block (RLB) are recent techniques used for pain…
- Trial name
- NCT06653803
- Testing
- Rhomboid Intercostal Block (RIB), Retrolaminar Block (RLB)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Pain, Acute Post-Operative, Dexmedetomidine
Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological Surgery
The aim of this study is to investigate and compare the effects of a continuous infusion of low-dose esmolol and dexmedetomidine versus placebo on intraoperative and postoperative opioid consumption and analgesic efficacy in…
- Conditions
- Pain, Acute Post-Operative, Dexmedetomidine, Analgesia, Esmolol
- Trial name
- NCT07846722
- Testing
- Esmolol hydrochloride, Dexmedetomidine, Normal (0.9%) saline
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Vasiliki Samartzi
Spine Surgery
The MDK Study: Using a Combination of Methadone-dexmedetomidine-ketamine for Postoperative Pain Control in Patients Undergoing Complex Spine Surgeries.
This study will investigate whether a combination of three anesthetic medications will reduce intraoperative and postoperative pain in patients undergoing complex spine surgery, and whether it will reduce the use of opioid pain…
- Trial name
- NCT07365800
- Testing
- Methadone-dexmedetomidine-ketamine combination
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- University of Missouri-Columbia