Clinical trials: Post Partum Haemorrhage
Post Partum Hemorrhage
Feasibility Clinical Investigation Using the InPress Device for the Treatment of Postpartum Hemorrhage
Feasibility trial of the InPress Device to treat postpartum hemorrhage (PPH).
- Trial name
- NCT04364386
- Testing
- InPress Device
- Where
- 2 sites in Indonesia
- Volunteers
- 10 people
- Sponsor
- Alydia Health
Hemorrhage Postpartum, Fertility Disorders
Fertility After Intrauterine Tamponing Balloon: Where Are we
Today, few data are available on the patient's fertility following intrauterine tamponade balloon (BTIU) used for postpartum hemorrhage (PPH) after vaginal delivery (AVB).
- Trial name
- FERTIBTIU (NCT04133402)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- University Hospital, Lille
Post Partum Haemorrhage in Patients Undergoing Cesarean Section
Evaluation of Melatonin's Effect on Pain and Blood Loss After Cesarean Section
The purpose of this study is to assess the effect of melatonin on pain and amount of blood loss after cesarean delivery one hundred twenty women with singleton term pregnancy undergoing elective or emergency lower segment…
- Trial name
- NCT01572805
- Testing
- melatonin 3mg, melatonin 6mg
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Qazvin University Of Medical Sciences
Postpartum Hemorrhage, Immediate
Minimum Effective Duration of Intrauterine Balloon Tamponade for the Management of Postpartum Hemorrhage
Intrauterine balloon tamponade (IUBT) is recommended worldwide as the second-line therapy to treat postpartum hemorrhage. While much literature demonstrates the effectiveness of this therapy, little is known about how long the…
- Trial name
- NCT04467996
- Testing
- Intrauterine balloon tamponade
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Denver Health and Hospital Authority
Uterine Atony, Postpartum Hemorrhage
Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT
This is a double-blind 3-arm randomized clinical trial to determine whether higher dose oxytocin regimens (compared to the standard regimen) reduce the frequency of uterine atony and postpartum hemorrhage after vaginal delivery.
- Trial name
- NCT00790062
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 1,798 people
- Sponsor
- University of Alabama at Birmingham
Postpartum Hemorrhage
rhuFVIIa in Post-partum Hemorrhage
The aim of this clinical research project is to evaluate the use of the recombinant human activated factor VII (rhFVIIa), given as a salvage therapy, in women with a dramatic postpartum hemorrhage still ongoing after all the…
- Trial name
- NCT00370877
- Testing
- rFVIIa, Standard Care
- Where
- 8 sites in France, Switzerland
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Uterine Atony, Postpartum Hemorrhage
An Evidence Based Protocol for Oxytocin Administration in Vaginal Delivery
The purpose of this study will be to evaluate a standardized, evidence-based protocol versus a conventional approach for the dosing of oxytocin in vaginal delivery.
- Trial name
- NCT02410655
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Postpartum Hemorrhage
Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH
The aim of this study is to compare the effect of low dose of Tranexamic acid (1gm) and Ethamsylate (1gm) after prophylactic oxytocin administration versus placebo with prophylactic oxytocin given in the 2 minutes after child…
- Trial name
- NCT02604719
- Testing
- Tranexamic Acid and Ethamsylate
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ahmed Alanwar
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Preeclampsia Severe
Uterotonics for Severe Preeclampsia
The study compares the effect of Intravenous carbetocin versus combined use of intravenous oxytocin and rectal misoprostol for prevention of postpartum hemorrhage during delivery of women with severe preeclampsia
- Trial name
- NCT04756661
- Testing
- Carbetocin, Oxytocin, Misoprostol
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Assiut University
Placenta Previa
Mostafa Maged Technique to Control and Prevent the Post-Partum Bleeding From the Lower Uterine Segment in Placenta Previa Cases
Post - partum haemorrhage is still a headache to all obstetricians around the whole world . Every obstetrician exerts his own full effort to control bleeding which can occur post-partum by applying all maneuvers to preserve the…
- Trial name
- NCT05283122
- Testing
- Mostafa Maged Technique
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Postpartum Haemorrhage (PPH), PPH
EVE TRIAL , ALMA SYSTAM
abnormal bleeding after childbirth. This condition is called abnormal bleeding and becomes a condition known as postpartum hemorrhage (PPH) when worsens.
- Conditions
- Postpartum Haemorrhage (PPH), PPH, Postpartum Hemorrhage (Primary)
- Trial name
- EVE (NCT06646653)
- Testing
- Alma System
- Where
- 2 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- ResQ Medical Ltd
Cesarean Section Complications
Topical Tranexamic Acid for the Prevention of Postpartum Hemorrhage in Women With Twin Pregnancy
twin pregnant women requesting cesarean section, the effectiveness and safety of temporary uterine packing coupled with topical tranexamic acid as an adjuvant for decreasing blood loss during delivery were compared to placebo.
- Trial name
- NCT05072873
- Testing
- Topical tranexamic acid, normal saline
- Volunteers
- 150 people
- Sponsor
- Aswan University Hospital
Delayed and Secondary Postpartum Hemorrhage
Immediate vs Delayed Postpartum Implanon-NXT
This prospective observational cohort study aims to compare immediate postpartum insertion (within 72 hours after delivery) versus delayed insertion (4-6 weeks postpartum) of the etonogestrel subdermal implant (Implanon-NXT®️)…
- Trial name
- NCT07626502
- Testing
- Etonogestrel subdermal implant (Implanon-NXT®)
- Volunteers
- 90 people
- Sponsor
- Assiut University
Delivery
Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Delivered Vaginally With at Least 2 Risk Factors for Atonic PPH: A Randomised Controlled Trial
250 women will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Carbetocin 100 µgm (Pabal® Ferring, UK) and group 2 will receive oxytocin 5IU (Syntocinon®, Novartis…
- Trial name
- PPH (NCT02304042)
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Primary Postpartum Hemorrhage, Administration of Sulprostone
Vacuum Device for Hemostasis in Obstetrics and Gynecology
Postpartum hemorrhage (PPH), is the leading cause of maternal mortality and is responsible for approximately 25% of maternal mortality deaths.It is defined as blood loss in excess of 500 ml following vaginal childbirth.
- Conditions
- Primary Postpartum Hemorrhage, Administration of Sulprostone, Vaginal Childbirth
- Trial name
- HEMOGYN2 (NCT02816203)
- Testing
- Hemostatic Intra-Uterine suction cup
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Postpartum Hemorrhage
The Foley's Catheter Balloon to the Bleeding From Placenta Previa
Post-partum haemorrhage due to placenta previa is usually from the placental bed at the lower uterine segment and it occurs after the placenta separation.
- Trial name
- NCT02640885
- Testing
- Foley's cather ballon
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Postpartum Hemorrhage
Prevention of Postpartum Haemorrhage With Sublingual Misoprostol or Oxytocin
Sublingual misoprostol produces rapid peak concentration and is more effective than oral misoprostol for prevention of excessive postpartum bleeding.
- Trial name
- NCT01373359
- Testing
- Misoprostol, Oxytocin
- Where
- India
- Volunteers
- 652 people
- Sponsor
- Jawaharlal Nehru Medical College
Post Partum Hemorrhage
Use of TXA to Prevent Postpartum Hemorrhage
Postpartum hemorrhage (PPH) occurs in up to one in ten deliveries worldwide and is the leading cause of maternal morbidity and mortality.
- Trial name
- TAPPH-1 (NCT03069859)
- Testing
- TXA (1g)
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Sunnybrook Health Sciences Centre
Coagulation Defect; Puerperal, Post Partum Hemorrhage
Bedside Assessment of Coagulation in Post-partum Hemorrhage by Thromboelastography (TEG ®6S)
Postpartum hemorrhage (PPH) is one of the leading causes of maternal deaths. Its prognosis is directly influenced by the early diagnosis and treatment of the associated coagulopathy.
- Conditions
- Coagulation Defect; Puerperal, Post Partum Hemorrhage, Blood Protein Disorders, Pregnancy Hemorrhage
- Trial name
- HPPTEG6S (NCT03592303)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris