Clinical trials: Post Pulmonary Resection
Thoracic Surgery
Ultrasound-Guided Serratus Anterior Plane Block for Additional Pain Relief After Lung Surgery
The purpose of this study is to see if an anesthesia technique called serratus anterior plane block may provide additional pain relief for the chest wall after lung surgery.
- Trial name
- NCT04238455
- Testing
- Serratus anterior plane block
- Where
- 6 sites in United States
- Volunteers
- 93 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pneumothorax
Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax
Sunnybrook Health Sciences Center annually provides assistance to approximately 600 cardiac surgeries and 1500 trauma patients, many of whom require chest tubes to prevent blood and fluids from accumulating in the pleural…
- Trial name
- LUSvsCXR (NCT06022081)
- Testing
- Lung ultrasound to detect pneumothorax.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Malignant Mesothelioma
Cisplatin, Interferon Alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00003263
- Testing
- recombinant interferon alfa, cisplatin, surgical procedure
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Fox Chase Cancer Center
Lung Cancer (NSCLC)
Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection
This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection.
- Trial name
- NCT07841249
- Testing
- Lobectomy, Sublobar Resection
- Where
- China
- Volunteers
- 604 people
- Sponsor
- Tongji Hospital
Lung Cancer
Lung cAncer Robotic Comparative Study
To compare outcomes of minimally invasive surgical techniques for the treatment of early-stage non-small cell lung cancer.
- Trial name
- LARCS (NCT06038227)
- Testing
- Robotic Assisted Thoracic Surgery, Video Assisted Thoracic Surgery
- Where
- 13 sites in Denmark, France and 5 more
- Volunteers
- 600 people
- Sponsor
- Intuitive Surgical
Thoracic Surgery
Assessment in Patients After Thoracic Surgery
Lung cancer is the leading cause of death in men and the second in women with a 5 year survival in Europe of less than 15%. One of the methods most used for its treatment is pulmonary resection.
- Trial name
- NCT03300622
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Pulmonary Nodule, Pneumothorax
Safety And Recovery Of Tubeless Strategy In Uniportal VATS Wedge Resection
Brief Summary The goal of this clinical trial is to evaluate the safety and recovery outcomes of different tubeless strategies in adult patients undergoing uniportal video-assisted thoracoscopic (VATS) wedge resection who are…
- Conditions
- Pulmonary Nodule, Pneumothorax, Postoperative Complications
- Trial name
- NCT07395349
- Testing
- Conventional Chest Tube Drainage, Single Intraoperative Aspiration Tubeless, Double Intraoperative Aspiration Tubeless
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Venous Thrombosis, Pulmonary Embolism
Extended Out-of-hospital Low-molecular-weight Heparin Prophylaxis Against DVT and PE in Patients Undergoing Major Lung Resection
Postoperative venous thromboembolism (VTE) is a significant health-care problem, resulting in significant morbidity, mortality and resource utilization. The true incidence is unknown, and may range from 1% to 15%.
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Lung Neoplasms
- Trial name
- NCT02258958
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- McMaster University
Lung Function
Lung Function After Robot-assisted Radical Prostate Ectomy
The aim of our study is to investigate if the use of the AirSeal insufflation system impairs the lung function of patients less than a conventional system in patients undergoing robot-assisted laparoscopic radical prostatectomy…
- Trial name
- NCT02066246
- Testing
- AirSeal, Olympus UHI-3
- Where
- 2 sites in Germany
- Volunteers
- 192 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Carcinoma, Non-Small-Cell Lung, Quality of Life
QOL After SURGERY and ADJUVANT Treatment
The goal of this prospective, observational study is to measure and analyze the effect of adjuvant treatment over the quality of life and recovery of patients undergoing pulmonary resection because of non-small cells lung cancer…
- Trial name
- NCT06115239
- Testing
- Questionnaires
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of Salamanca
Atrial Fibrillation, Neuropathic Pain
Atrial Fibrillation and Neuropathic Pain After Thoracotomy and Continuous Application of Magnesium Sulphate.
Atrial fibrillation and chronic neuropathic pain are adverse events occurring after posterolateral thoracotomy for lung resection. The continuous application of magnesium sulphate may have a prophylactic effect.
- Trial name
- NCT02008747
- Testing
- Magnesium sulphate
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Postoperative Sleep Disturbances, Chronic Post-surgical Pain
Effectiveness of Perioperative Percutaneous Acupuncture on Postoperative Sleep Disturbances and Chronic Pain in Patients Undergoing Video-Assisted Thoracoscopic Lung Cancer Resection: A Prospective, Randomized, Single-Blind, Superiority Controlled Trial
This study evaluates whether acupuncture at specific body points before and after surgery can improve sleep quality and reduce long-term postoperative pain in patients undergoing video-assisted thoracoscopic lung cancer…
- Trial name
- PASA-VATS (NCT07662733)
- Testing
- Percutaneous Acupoint Acupuncture
- Where
- 2 sites in China
- Volunteers
- 316 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Recurrence Tumor, Opioid Use, Unspecified
Analgesia aNd caNcer recUrrence Lung cAncer Resection
The choice of analgesia after cancer surgery may play a role in the onset of recurrence, particularly opioids seem to play a role in the immune system by promoting cancer cell proliferation and migration.
- Conditions
- Recurrence Tumor, Opioid Use, Unspecified, Analgesia, Thoracic Surgery
- Trial name
- NCT04656769
- Testing
- Peridural analgesia
- Where
- Italy
- Volunteers
- 382 people
- Sponsor
- University of Turin, Italy
Magnesium Sulphate, Post Pulmonary Resection
Magnesium Infusion for Pain Relief After Thoracotomy. A Randomized Controlled Trial.
All patients were premedicated with oral midazolam 5-15 mg. one hour before surgery. General anesthesia with double lumen endobronchial tube was given. Patient was induced by propofol and fentanyl.
- Conditions
- Magnesium Sulphate, Post Pulmonary Resection, Pain
- Trial name
- NCT01261702
- Testing
- magnesium sulphate
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Lung Neoplasms, Pulmonary Surgical Procedures
Staple-line Reinforcement for Prevention of Pulmonary Air Leakage
The aim of this study is to compare the efficacy of FORESEAL with stapling alone or associated with tissue sealant or glue in terms of air leakage duration after lung resection for cancer.
- Conditions
- Lung Neoplasms, Pulmonary Surgical Procedures, Surgical Staplers, Tissue Adhesives
- Trial name
- SPIRAL (NCT00925444)
- Testing
- FOREseal, Stapling
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Respiratory Failure
Lung Aeration After Flexible Bronchoscopy in Intubated Critically Ill Patients
In patients suffering from acute respiratory failure, ineffective cough and the consequent retention of secretions are common clinical problems, which often lead to the need for tracheostomy for the sole purpose of aspiration of…
- Trial name
- NCT05200494
- Testing
- Recruiting Maneuver
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University Magna Graecia
Pain, Decreased Lung Function
ThOracoscopic Wedge Resection Treated With Chest Tube Removal Intraoperatively
Chest tubes are used routinely although preliminary studies demonstrate the feasibility and safety of intraoperative chest drain removal. Previous studies are however either retrospective or mainly concerning benign disease.
- Conditions
- Pain, Decreased Lung Function, Delayed Discharge
- Trial name
- TOTTI (NCT02829736)
- Testing
- Intraoperative sealing test, Standard post-operative chest tube, Intraoperative chest tube removal
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hepatocellular Carcinoma, Renal Cell Carcinoma
Safety Study of Cord Blood-derived Cytokine-induced Killer Cells in Patients With Solid Tumor After Radical Resection
Cytokine-induced killer (CIK) cells are a heterogeneous subset of ex-vivo expanded T lymphocytes which present a mixed T-NK phenotype and are endowed with a major histocompatibility complex-unrestricted antitumor activity.
- Conditions
- Hepatocellular Carcinoma, Renal Cell Carcinoma, Lung Cancer
- Trial name
- NCT01914263
- Testing
- cytokine induced killer cell
- Where
- 3 sites in China
- Volunteers
- 40 people
- Sponsor
- Alliancells-PuRui Biocience Co., Ltd.
Pulmonary Resection, Right Ventricular Function
Effects of Pulmonary Resection on Right Ventricular Function
Lung resection is associated with high postoperative morbidity and mortality and leads to a significant long-term decrease in functional capacity, particularly due to cardiorespiratory complications.
- Conditions
- Pulmonary Resection, Right Ventricular Function, Echocardiography, Cardiothoracic Anesthesia
- Trial name
- NCT07042893
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Çağrı Özdemir