Clinical trials: Post Pulmonary Resection
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Lung Non-Small Cell Carcinoma
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment
This phase II trial compares the effect of intensity-modulated post-operative radiation therapy (I²-PORT) followed by standard of care therapy (chemotherapy or immunotherapy) to standard of care therapy alone in treating patients…
- Trial name
- NCT07293247
- Testing
- Chemotherapy, Immunotherapy, Intensity-Modulated Radiation Therapy
- Where
- 111 sites in United States
- Volunteers
- 164 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Persistent Cough, Pneumonectomy
Analysis of Factors and Treatment Related to Chronic Cough After Pulmonary Resection
Surgical resection is the primary treatment for pulmonary tumors. Surgeons has been frequently concerned about effectiveness, safety, and minimal invasive techniques.
- Conditions
- Persistent Cough, Pneumonectomy, Lung Neoplasms
- Trial name
- NCT05586035
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Lung Cancer
Post-Market Study of Transbronchial Cryo-assisted RFA During Robotic Bronchoscopy With Subsequent Surgical Resection
The purpose of this study is to confirm the procedural feasibility and device usability of the HybridTherm® system during bronchoscopic cryo-assisted radiofrequency ablation (RFA) performed prior to scheduled surgical resection…
- Trial name
- CRONOS-CH (NCT07398027)
- Testing
- HybridTherm® System
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Carolin Steinack
Carcinoma, Non-Small-Cell Lung
Comprehensive Geriatric Assessment and Complications Following Lung Resection for Lung Cancer
schema : Prospective prognostic study The main objective is to study the value of the Comprehensive Geriatric Assessment in predicting the risk of post operative complications after lung resection for cancer.
- Trial name
- OPERAGE (NCT01956331)
- Where
- 25 sites in France
- Volunteers
- 302 people
- Sponsor
- Groupe Francais De Pneumo-Cancerologie
Arrhythmia
Does Atorvastatin Prevent Post Operative Atrial Fibrillation After Pulmonary Resection: A Randomized Clinical Study
The purpose of this study is to determine if atorvastatin (Lipitor) reduces the occurence of abnormal heart rhythm (atrial arrhythmia) following non cardiac thoracic surgery.
- Trial name
- NCT00756886
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
PONV
Comparison Between Opioid-Free Anaesthesia Versus Opioid Based Anesthesia in Reduction Postoperative Nausea and Vomiting (PONV)After Thoracoscopic Lung Resection.
The invistigators hypothesized that a protocolized OFA technique would lower the occurance of PONV in patients undergoing thoracoscopic lung surgery compared to standard opioid-based anaesthesia.
- Trial name
- NCT07806162
- Testing
- Opioid Free Anaesthesia, conventential opioid-based anaesthesia (OBA,
- Volunteers
- 120 people
- Sponsor
- Sohag University
Non-small Cell Lung Cancer
Radiation Therapy in Treating Patients With Non Small Cell Lung Cancer That Has Been Completely Removed by Surgery
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Trial name
- LUNG ART (NCT00410683)
- Testing
- clinical observation, adjuvant therapy, 3-dimensional conformal radiation therapy
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Brain Metastases, Adult, Non Small Cell Lung Cancer
SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)
This study aims to evaluate the efficacy of silibinin in preventing recurrence in the brain after complete resection of a brain metastasis (BM) from non-small-cell lung cancer (NSCLC) or breast cancer (BC).
- Conditions
- Brain Metastases, Adult, Non Small Cell Lung Cancer, Breast Cancer
- Trial name
- SILMET (NCT05689619)
- Testing
- Silibinin
- Where
- 6 sites in Italy
- Volunteers
- 70 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Prolonged Air Leak, Lung Resection
Effectiveness Novel Tissue Sealant, Prevention Prolonged Air Leak (PAL) After Lung Resection
The effectiveness of tissue sealants to prevent Prolonged Air Leak (PAL) after lung resection procedures remains unproved. The investigators hypothesize that one of the main reasons for that is the heterogeneity of previously…
- Trial name
- NCT02491671
- Testing
- Hemopatch, standard preventive measures
- Where
- 6 sites in Spain
- Volunteers
- 260 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Non-small Cell Lung Cancer Stage Ⅱ, Non-small Cell Lung Cancer Stage ⅢA
Clinical Observation of S1 Capsule for Stage Ⅱ-ⅢA Non-small Cell Lung Cancer After Complete Resection
The purpose of this study is to evaluate S1 capsule plus Cisplatin as adjuvant treatment in stageⅡ and Ⅲa non-small cell lung cancer.
- Trial name
- S1VSNP (NCT02223611)
- Testing
- S1 capsule, Vinorelbine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hebei Medical University Fourth Hospital
Lung Cancer
Risk Factors for Postoperative Cough in Patients Undergoing Thoracoscopic Lung Resection
Lung cancer, as the main cause of cancer-related deaths in both males and females, is a great risk to human health. Pulmonary resection is the most applicable to early-stage lung cancer diagnoses and considered the best curative…
- Trial name
- NCT06476249
- Testing
- without
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Hematology department of the 920th hospital
Postoperative Pain, Lung Cancer
Postoperative Pain Management on Patients Undergoing Lung Tumor Resection
Multimodal analgesia (MMA) is an essential part of Enhanced Recovery After Surgery (ERAS) protocol. The principle of MMA is to manage pain with analgesics of multiple classes acting on distinct target sites through different…
- Conditions
- Postoperative Pain, Lung Cancer, Lung Tumor
- Trial name
- NCT06397807
- Testing
- Dinalbuphine sebacate, Analgesic injectables, Enteral analgesics
- Volunteers
- 400 people
- Sponsor
- China Medical University Hospital
Lung Cancer, Nonsmall Cell
Pulmonary Function After Arterial Sleeve Lobectomy
Lung cancer is the leading cause of cancer death worldwide. Despite the evolution of medical and multimodal treatments, surgical treatment remains the curative management in the localized cancer.
- Trial name
- NCT04981938
- Testing
- Lobectomy with pulmonary artery reconstruction
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional Universitaire Montpellier
Carcinoma, Non-Small-Cell Lung
Chemotherapy of NSCLC With or Without Icotinib
Epidermal growth factor receptor (EGFR) mutations occur in up to 50% of Asian patients with non-small cell lung cancer (NSCLC). Treatment of advanced NSCLC patients with EGFR-tyrosine kinase inhibitors (EGFR-TKI) confers a…
- Trial name
- NCT02430974
- Testing
- Icotinib
- Volunteers
- 50 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Lobectomy, Segmentectomy
Evaluating the Association of Force Feedback With Outcomes After Lung Resection Using the da Vinci Multiport System
The purpose of this research is to study patient outcomes based on the use of Force Feedback instruments during robotic-assisted lung resection.
- Conditions
- Lobectomy, Segmentectomy, Force Measurement
- Trial name
- NCT07660900
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Ohio State University
Postoperative Cognitive Dysfunction, Acute Postoperative Pain
Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients
To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.
- Conditions
- Postoperative Cognitive Dysfunction, Acute Postoperative Pain, Chronic Postsurgical Pain
- Trial name
- NCT05364216
- Testing
- Measurement of cognitive function, Thoracic paravertebral block, The assessment of cognitive function
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Non-small Cell Lung Cancer
The Recurrence Gene Profiles of Adjuvant Osimertinib Therapy in Resected Non-Small-Cell Lung Cancer
This study was a multicenter, real-world observational study aimed at characterizing the genomic landscape of recurrence in patients with EGFR-sensitizing mutation-positive early-stage (clinical stage IB-IIIA) non-small cell lung…
- Trial name
- RAISE (NCT06477055)
- Where
- 2 sites in China
- Volunteers
- 43 people
- Sponsor
- Hunan Province Tumor Hospital
Colon Cancer
Colon Cancer Prognosis After Radical Surgery
1. Radical surgery. It is supposed to improve prognosis of colon cancer. A surrogate measure of achievement of radical surgery is the number of lymph nodes removed with the specimen. 2. Markers.
- Trial name
- NCT00963352
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Haraldsplass Deaconess Hospital