Clinical trials: Post Stroke
To Healthy Volunteer, Virtual Lesions for Aphasia
Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types
Repetitive transcranial magnetic stimulation induced virtual lesions for aphasia.
- Trial name
- NCT01877161
- Testing
- Repetitive magnetic stimulation to superior temporal gyrus, Repetitive magnetic stimulation to middle temporal gyrus
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Hemorrhagic Stroke, Hemiparesis
Dual Transcranial Direct Current Stimulation (dTDCS)-Enhanced Therapy After Hemorrhagic Strokes and VEGF
This study will evaluate the feasibility of dual tDCS to improve arm motor function in chronic stroke patients. In addition it will collect pilot data on the blood biomarkers associated with treatment effect.
- Trial name
- NCT03857243
- Testing
- dual transcranial direct current stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Stroke
Power Training Post-stroke
Hemiparesis, strictly defined as (muscular) weakness affecting one side of the body, is seen in three-quarters of individuals following stroke.
- Trial name
- NCT01970592
- Testing
- POWER training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
Stroke (795,000/year in the US and 30 million existing stroke survivors in the world) damages brain neural structures that control coordinated upper limb movement.
- Trial name
- NCT02856035
- Testing
- Neural feedback plus FES and motor training
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Cerebrovascular Accident
Spinal Plasticity to Enhance Motor Retraining After Stroke
The objective of this project is to study the effects of an emerging noninvasive neuromodulation strategy in human stroke survivors with movement-related disability.
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT03645122
- Testing
- Paired corticospinal-motoneuronal stimulation (PCMS)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
CVA (Cerebrovascular Accident)
Incline Training to Personalize Motor Control Interventions After Stroke
This study will evaluate the use of incline and decline treadmill training to address specific motor control deficits identified within different post-stroke walking patterns.
- Trial name
- NCT03561246
- Testing
- Incline treadmill walking, Decline treadmill walking, Level Treadmill (Control)
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-stroke Depression
SCED - Wisdom Enhancement for Post-Stroke Depression
One-third of stroke survivors experience post-stroke depression, but there are currently no official guidelines for supporting them.
- Trial name
- WE-PSD (NCT06451965)
- Testing
- Timeline Intervention
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Stroke
Objective Assessment of Upper Extremity Functioning of Stroke Patients Before and After Rehabilitation
The purpose of this study is to evaluate by objective measures the improvement in upper extremity functioning, as reflection of motor learning, in stroke patients in the sub acute phase.
- Trial name
- AssStrFunc (NCT02092662)
- Testing
- stroke, Healthy controls
- Where
- Israel
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Carmeli Eli
Stroke
Improving Rehabilitation by Magnetic Brain Stimulation
We hope to understand the properties of the motor cortex in the brain of people with stroke using non-invasive magnetic stimulation.
- Trial name
- NCT00636701
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cerebral Stroke, Hemiplegia, Spastic
Compensatory Kinematic Movements in Various Directions After Stroke
This is cross-sectional study. By comparing kinematic analysis between stroke and healthy subjects in various directions, this investigation analyzes the compensatory kinematic movement for reaching task in stroke survivors
- Trial name
- NCT05683158
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Perceptual-motor Interaction to Improve Bimanual Coordination After Stroke
Significant difficulty in incorporating the weaker arm in daily activities after stroke is, in part, driven by difficulty in engaging both arms interactively in a coordinated manner.
- Trial name
- Bimanual (NCT03755076)
- Testing
- Perceptual cuing
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Stroke, Sensorimotor Impairment
Learning in Stroke
After a stroke, plasticity occurs in the brain from microscopic to network level with positive but also negative consequences for functional recovery.
- Trial name
- NCT05511467
- Testing
- Visuomotor learning task
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stroke, Healthy Adult
Tracking Post-stroke Walking Improvements From the Clinic Into the Home
The purpose of this proposal is to use novel video-based movement tracking technology to measure gait quality after stroke - in the home.
- Trial name
- NCT05454007
- Testing
- Step length asymmetry training
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke
Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke
Of the ~700,000 persons who suffer a stroke each year, only 50% recover the ability to perform unlimited community walking. One mechanism contributing to locomotor dysfunction post-stroke is an increased metabolic cost of walking…
- Trial name
- NCT00721357
- Testing
- Treadmill walking, Magnetic resonance spectroscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Premotor Cortex: A New Target for Stroke Motor Rehabilitation
The goal of the study is to determine the effect of repetitive transcranial magnetic stimulation (rTMS) over the premotor cortex on training-related improvements in motor performance and associated neural plasticity.
- Trial name
- NCT02565199
- Testing
- rTMS Over Contralateral Hemisphere of Premotor Cortex, rTMS Over Ipsilateral Hemisphere of Premotor Cortex, Control 1: rTMS Timed 400 ms After Movement-related EMG
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Emory University
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Stroke
Understanding Different Parameters in Locomotor Training (a Type of Walking Training) for Person After a Stroke
This is a research study to understand how people who have experienced a stroke walk in order to develop better and more effective types of therapy.
- Trial name
- NCT00712179
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development