Clinical trials: Post Stroke Recovery
Acute Ischaemic Stroke
Combined tDCS+PNS After Acute Stroke
Recent work showed that application of peripheral nerve and cortical stimulation independently can induce 10-15 % improvement in motor performance in patients with chronic stroke.
- Trial name
- NCT01207336
- Testing
- combined transcranial direct current stimulation and electrical peripheral nerve stimulation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cerebrovascular Disorders, Memory
Roflumilast to Treat Cognitive Sequela After Stroke
The aim of the current project is to validate the effects of chronic rolflumilast treatment (12 weeks) on cognitive functions (i.e.
- Conditions
- Cerebrovascular Disorders, Memory, Functional Recovery, Drug Intervention
- Trial name
- ROSTMEMA (NCT04854811)
- Testing
- Roflumilast Oral Tablet
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Maastricht University
Stroke, Inpatients
A Novel Approach to Enhance True Recovery After Stroke
The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies.
- Conditions
- Stroke, Inpatients, Recovery of Function, Observational Study
- Trial name
- NCT05359367
- Testing
- Observational
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Danderyd Hospital
Stroke
Stroke Rehabilitation, Functional Recovery, and Cost-effectiveness
The investigators will determine the client and non-client variables associated with discharge to an inpatient rehabilitation facility vs. skilled nursing facility in individuals' post-stroke.
- Trial name
- NCT04279977
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Stroke
Telerehabilitation and Biomarkers of Recovery After Stroke in Brazil
The purpose of this research study is to provide preliminary evidence of whether telerehabilitation targeting arm movement, when added to usual care, improves arm function and reduces global disability after stroke, compared to…
- Trial name
- TR-BR-1 (NCT07646522)
- Testing
- Telerehabilitation, Usual Care
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Joint Loose Bodies
Different Methods of Physical Therapy for Stroke
It is estimated that worldwide, about 15 million people are affected by vascular accident (CVA) per year, and in Brazil, the stroke is a major cause of death and disability, generating too much economic and social impact by…
- Trial name
- NCT02932631
- Testing
- THERAPY CONTROL AND MOVEMENT OF INDUCTION
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Stroke
Evaluation of Whether Functional Strength Training Can Enhance Recovery of Mobility After Stroke
The purpose of this study is to test the hypothesis that adding functional strength training to UK conventional therapy improves muscle function and walking than either UK conventional therapy alone or increased intensity of UK…
- Trial name
- NCT00322192
- Testing
- Conventional UK Physical therapy, Increased intensity of UK conventional physical therapy, UK conventional physical therapy plus functional strength training
- Where
- 4 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- St George's, University of London
Stroke, Hemiparesis
Electrical Stimulation for Recovery of Ankle Dorsiflexion in Chronic Stroke Survivors
Ankle dorsiflexor weakness (paresis) is one of the most frequently persisting consequences of stroke. The purpose of this exploratory study is to compare two different treatments -- Contralaterally Controlled Neuromuscular…
- Conditions
- Stroke, Hemiparesis, Lower Extremity Paresis
- Trial name
- NCT01029912
- Testing
- Electrical stimulator
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- MetroHealth Medical Center
Hemispatial Neglect
Sleep as a Model to Understand and Manipulate Cortical Activity in Order to Promote Functional Recovery After Stroke
Brain functions are supported by multiple cell types, including neuronal and non-neuronal cells that are connected into complex networks.
- Trial name
- SSS (NCT03090711)
- Testing
- Transcranial Magnetic Stimulation (TMS), Transcranial Alternating Current Stimulation (tACS)
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke
Electroacupuncture and rTMS for Post-Stroke Motor Recovery
This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA.
- Trial name
- NCT07113990
- Testing
- Active EA, Active rTMS
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Jing Tao
Stroke
Locomotor Recovery and Compensation Post-stroke (LRC)
The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke.
- Trial name
- LRC (NCT05081713)
- Testing
- high-intensity training focused on stepping in variable contexts
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Stroke Patients, Stroke
Feasibility of a Physiotherapy Programme, With Integrated telerehabIlitation to Increase Rehabilitation Time and Improve Motor Function
About two thirds of people after stroke have some level of disability. Rehabilitation helps to reduce disability and supports people to return to a meaningful life.
- Trial name
- PRACTISE (NCT06871878)
- Testing
- PRACTISE Physiotherapy Intervention
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Glasgow Caledonian University
Aphasia Non Fluent, Stroke
Sensory-Motor Integration for Speech Rehabilitation in Patients With Post-stroke Aphasia
SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging and engineering sciences) that…
- Trial name
- SEMO (NCT04433351)
- Testing
- Enriched rehabilitation, Simple rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Stroke, Ischemic
Marker for Stroke Recovery
This study aims to develop a neurophysiological marker for post-stroke participants that predicts upper extremity motor recovery in response to a standard upper extremity rehabilitation protocol of task-specific training (TST).
- Trial name
- NCT05256368
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Cerebral Infarction
Study of NeuroAid In Enhancing Recovery After Stroke
TIERS is a phase II to generate detailed preliminary data on the efficacy of NeuroAid in post-stroke recovery, and to assess the utility of the rehabilitation outcome measure instruments used.
- Trial name
- TIERS (NCT00721825)
- Testing
- Neuroaid
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Moleac Pte Ltd.
Stroke
Mirror Therapy After Stroke: A Dosing Study
It has been suggested that augmenting repetitive task practice with the use of box (mirror) therapy (BT) can enhance the benefits of task practice and may provide stroke survivors an opportunity to engage in self-directed…
- Trial name
- NCT02778087
- Testing
- Mirror Box Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Columbia University
Acute Ischemic Stroke, Intracranial Hemorrhage
Hemodynamic in Postreperfusion Period and Functional Recovery in Acute Ischemic Stroke Patients
The investigators are suggtesting that lower goals of systolic blood pressure after intravenous thrombolysis may reduce the risk of hemorrhagic complications and improve functional outcomes after acute ischemic stroke.
- Trial name
- NCT05517109
- Testing
- Hemodynamic goal including lower goal of systolic blood pressure
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Northern State Medical University
Cerebrovascular Accident
Role of the Intact Hemisphere in Recovery of Motor Function After Stroke
The purpose of this study is to better understand the role of the motor part of the brain in the recovery of motor function after stroke. The motor deficits that follow a stroke are compensated for over several months.
- Trial name
- NCT00028184
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Ischemic Stroke
Navigated Transcranial Magnetic Stimulation in Monitoring Stroke Recovery
The past 10 years of research in persons more than 6 months post stroke have shown certain types of rehabilitation can help "re-wire" the brain.
- Trial name
- NCT01005394
- Testing
- Navigated TMS examination
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nexstim Ltd