Clinical trials: Post Surgical Wound
Venous Thromboembolism, Embolism and Thrombosis
Factor IX Inhibition in Thrombosis Prevention (The FIXIT Trial)
The purpose of this study is to determine whether TTP889 prevents venous thromboembolism following surgery to repair hip fracture.
- Conditions
- Venous Thromboembolism, Embolism and Thrombosis, Hip Fractures
- Trial name
- NCT00119457
- Testing
- TTP889
- Where
- 21 sites in Czechia, Denmark and 2 more
- Volunteers
- 300 people
- Sponsor
- vTv Therapeutics
Ascorbic Acid, Neurosurgical Procedures
Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery
The goal of this clinical trial is to investigate the effect of perioperative administration of vitamin C on postoperative pulmonary complications, with the aim of providing a safe and effective medication regimen for the…
- Conditions
- Ascorbic Acid, Neurosurgical Procedures, Humans, Ventilator-Induced Lung Injury
- Trial name
- NCT06421688
- Testing
- Ascorbic acid, Saline
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Qianfoshan Hospital
Myocardial Injury After Non-cardiac Surgery, Abdomen, Acute
Troponin I Level and Mortality in Acute Abdominal Surgery
The goal of this prospective cohort study is to estimate the incidence of myocardial injury after non-cardiac surgery (MINS) in patients undergoing acute high-risk abdominal surgery.
- Trial name
- NCT05933837
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Nordsjaellands Hospital
Cartilage Defects of the Knee
Long-term Safety and Efficacy of CartiFill After Microfracture Surgery in Knee Cartilage Defects
The purpose of this clinical trial is to evaluate the safety and efficacy of CartiFill implanted at the site of knee joint cartilage defect in a 6-year, long-term, follow-up investigation.
- Trial name
- NCT07621172
- Testing
- CartiFill, Microfracture
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Cellontech Co., Ltd.
Surgical Site Infection
Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
We are investigating outcome of antibiotic coated vicryl versus non coated vicryl in terms of rate of surgical site infection and lebgth of hospital stay in children after lalaprotomy for perforated viscera.
- Trial name
- NCT06129773
- Testing
- antibiotic coated vicryl used for fascial closure
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Muhammad Adeel Ashiq
Hip Fractures
Why Still in Hospital After Hip Fracture Surgery?
At our institution, hip fracture patients are admitted and treated according to a fast track patient pathway. The aim of this study is to identify areas of this patient pathway that can be improved.
- Trial name
- NCT03265275
- Testing
- Fast track patient pathway
- Where
- Norway
- Volunteers
- 182 people
- Sponsor
- University Hospital, Akershus
Arthroplasty, Knee Replacement, Wound Healing
Zip® Surgical Skin Closure Device vs. Staples for Skin Closure in Subjects Having Undergone Bilateral Knee Arthroplasty
Study designed to compare the Zip Surgical Skin Closure device vs. conventional staples for wound closure following bi lateral knee replacement surgery.
- Trial name
- NCT02460172
- Testing
- Zip Surgical Skin Closure, Steel Staples
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ZipLine Medical Inc.
Wound of Skin
Efficacy of Prophylactic Negative Pressure Wound Therapy (NPWT)
The role of prophylactic negative pressure wound therapy (NPWT) is promising in reducing wound-related complications. However, the prophylactic use of NPWT in reducing wound complications in patients who underwent conventional…
- Trial name
- EFESO (NCT05727995)
- Testing
- PICO7, usual care dressing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Sternal Wound Infection
Topical Vancomycin Over Sternal Edge in Cardiac Surgery
This is a single-blind 1:1 randomized controlled trial based on the hypothesis that topical application of vancomycin paste over sternum edge is safe and can reduce sternal wound infection after elective cardiac surgery.
- Trial name
- NCT04500275
- Testing
- Vancomycin Hydrochloride, Normal Saline
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Cheng-Kung University Hospital
Pneumothorax
Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax
Sunnybrook Health Sciences Center annually provides assistance to approximately 600 cardiac surgeries and 1500 trauma patients, many of whom require chest tubes to prevent blood and fluids from accumulating in the pleural…
- Trial name
- LUSvsCXR (NCT06022081)
- Testing
- Lung ultrasound to detect pneumothorax.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Delirium
A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Hip Fracture Repair Surgery
The purpose of this study is to evaluate the efficacy and safety of perioperative use of dexmedetomidine in the prevention of postoperative delirium in subjects undergoing surgery for fractured hip with general anesthesia.
- Trial name
- NCT00460473
- Testing
- Dexmedetomidine
- Where
- 30 sites in United States
- Volunteers
- 52 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Wound Healing Delayed
Microcurrent Therapy and Low-Level Laser Therapy on Wound Healing
The study aiming to compare between the Microcurrent and Low-Level Laser Therapy on wound healing
- Trial name
- NCT05326022
- Testing
- Microcurrent therapy, Low Level Laser Therapy, Medical therapy
- Volunteers
- 90 people
- Sponsor
- Nehad Ahmed Youness Abo-zaid
Acute Kidney Injury, Cardiac
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery: a Retrospective Monocentric Cohort Study
Cardiac surgery with cardiopulmonary bypass exposes patients to the risk of post-operative acute kidney injury. In the specific setting of cardiac surgery, acute kidney injury is often of multifactorial origindue to particular…
- Conditions
- Acute Kidney Injury, Cardiac, Surgery
- Trial name
- SGLT2i (NCT06453161)
- Testing
- Post-operative acute kidney injury
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Infection
Analysis of the Incidence of Post-Operative Wound Infections After Spine Surgery
Post-operative wound infections can prolong hospital stays, increase rates of readmission to the intensive care unit, and increase the costs of treatment significantly.
- Trial name
- NCT02891486
- Testing
- Spinal surgery
- Where
- 2 sites in United States
- Volunteers
- 6,959 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hemorrhoids
Effect of Red and Blue Light Irradiation on Wound Healing After Hemorrhoid Surgery
The subjects of this study were patients who took mixed haemorrhoidectomy during the period of December 2024 - December 2025 . The haemorrhoidectomy patients were randomly divided into routine group, red light group and red and…
- Trial name
- NCT07121686
- Testing
- Red light exposure, Red-blue light exposure
- Where
- China
- Volunteers
- 315 people
- Sponsor
- The Affiliated Hospital of Putian University
Liver Transplantation, Surgical Site Infection
Surgical Site Infections After Liver Transplantation Based on Perioperative Antibiotics
This study will be to prospectively determine differences in Surgical Site Infection (SSI) if a prolonged course of post-operative antibiotics are used following liver transplantation.
- Trial name
- NCT02717273
- Testing
- standard, extended, liver transplant
- Volunteers
- 102 people
- Sponsor
- University of Virginia
Appendicitis
Role of Wound Irrigation After Appendectomy
Surgical site infection is a common problem after open appendectomy. Irrigation of the surgical wound by topical antibiotics has been devised as a measure to reduce the incidence of wound infection.
- Trial name
- NCT03773224
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 179 people
- Sponsor
- Mansoura University
Pain, Postoperative, Gingival Diseases
Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery
When harvesting autogenous free grafts to treat periodontal conditions (e.g., lack of attached keratinized tissue, ridge defects, and other mucogingival deformities), the hard palate is the preferred donor site.
- Trial name
- NCT04957342
- Testing
- amnion-chorion membrane, Sutures
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Intra-operative Complications, Post Operative Complications
Single Incision Pelvic Floor Mesh Implants
Objectives: To evaluate whether the use of single incision un-anchored small mesh implants is feasible, safe and effective for women with moderate pelvic organ prolapse.
- Trial name
- NCT01909700
- Testing
- Single Incision Mesh
- Where
- Israel
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Perianal Abscess, Perianal Fistula
Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial
Most perianal abscesses (PA) result from an infection originating in anal crypts that extend into anal glands in the intersphincteric plane.
- Trial name
- PARFAIT (NCT04549311)
- Testing
- Antibiotic 1 arm (amoxicillin + clavulanic acid), Antibiotic 2 arm (ciprofloxacin + metronidazole)
- Where
- 3 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
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