Clinical trials: Post Surgical Wound
Acute Kidney Injury
Arterial Stiffness and AKI Post-CABG
Acute Kidney Injury is a condition where your kidneys suddenly stop working properly and usually occurs if you are already unwell with an illness and can happen after having surgery.
- Trial name
- Heart-AKI (NCT02364427)
- Testing
- Arterial stiffness - Vicorder to measure pulse wave velocity
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- King's College Hospital NHS Trust
Arthroplasty Complications, Amputation
Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings
Negative pressure dressings are currently widely used in wound management. Their use is gradually being extended to surgical scars.
- Conditions
- Arthroplasty Complications, Amputation, Prosthesis-Related Infections
- Trial name
- BERLYTZ (NCT04520841)
- Testing
- Prevena TM, Dry dressing
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Cesarian Scar, Surgical Site Infection (SSI)
Polyurethane Foam Versus Gauze Dressing After Cesarean Delivery in a Standardized Surgical Setting: A Prospective Randomized Controlled Trial
Background: Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and postoperative scar quality remains an important patient-centered outcome.
- Trial name
- CSWD_RCT (NCT07482202)
- Testing
- Polyurethane Foam dressing(Mepilex Border Flex), Conventional Gauze Dressing
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yewon Jung
Sepsis, Trauma Injury
Microbiome Dysfunction in Surgical Intensive Care Unit Survivors
Oral and gastrointestinal microbiome dysfunction has been demonstrated to be a culprit of various systemic dysfunctions in peripheries such as cardiovascular, nervous, endocrine and musculoskeletal systems.
- Trial name
- NCT05357170
- Testing
- Human feces collection
- Where
- United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Florida
Acute Kidney Injury
Preoperative Prediction of Acute Kidney Injury After Cardiac Surgery
Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk are lacking. Renal functional reserve (RFR), the capacity of the intact nephron mass to increase glomerular filtration rate…
- Trial name
- RFR (NCT03092947)
- Testing
- No intervention
- Volunteers
- 110 people
- Sponsor
- University of Giessen
Cognitive Dysfunction
Effects of Dexmedetomidine on Cognitive Outcome and Brain Injury Markers
Dexmedetomidine is a drug with sedative, anxiolytic, and analgesic properties. Benefits of its use covers good sedations without respiratory suppression, reduced circulating catecholamines due to decreased sympathetic…
- Trial name
- NCT03585452
- Testing
- Dexmedetomidine Infusion, Propofol based general anesthesia
- Where
- Poland
- Volunteers
- 23 people
- Sponsor
- Michał Kowalczyk
Colorectal Cancer, Neoadjuvant Chemotherapy
Camrelizumab Combined With Neoadjuvant Chemotherapy After Stent Placement for Left-Sided Obstructive Colonic Cancer
Patients with obstruction are associated with worse oncologic outcomes compared with those having nonobstructive tumors. Conventionally, patients with malignant large bowel obstruction receive emergency surgery, with morbidity…
- Conditions
- Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction
- Trial name
- NACSOC-02 (NCT05202314)
- Testing
- Immunotherapy (Camrelizumab)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Chao Yang Hospital
Spinal Deformity, Trauma
Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients
Surgical site infections (SSI) are not uncommon, especially in specific high-risk groups including spinal deformity and tumor (i.e. metastatic spine surgery) surgery.
- Conditions
- Spinal Deformity, Trauma, Spinal Tumor, Surgical Site Infection
- Trial name
- NCT03839914
- Testing
- Vancomycin powder
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Surgical Site Infection
Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections
Use of 2% chlorhexidine gluconate cloths pre-operatively and daily post-operatively jaw line to toes will decrease surgical site infections (SSI) by 30% when compared to patients who receive routine standard of care (use of…
- Trial name
- NCT02385708
- Testing
- 2% Chlorohexidine Gluconate Standard of Care, 2% Chlorohexidine Gluconate Chin to Toe
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Vanderbilt University
Postoperative Morbidity, Trauma
Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth
The proposed study will test the following hypotheses: 1. Pre-operative daily dual supplementation with Juice Plus+ (fruit \& vegetable) for 11 weeks will result in reduced post-operative morbidity in terms of quality of life…
- Conditions
- Postoperative Morbidity, Trauma, Wound Healing
- Trial name
- FAVOURITE (NCT01145820)
- Testing
- Juice plus
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- University of Birmingham
Acute Kidney Injury
PREdicting RENAL Injury In Patient After Hip Fracture Surgery
To determine whether MALDI, a type of Mass-Spectometry, can use protein pattern detection within urine to predict postoperative (after an operation) kidney damage in adults who have undergone emergency hip fracture surgery?
- Trial name
- PRE-RENAL (NCT03049150)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Skull Base Neoplasms, Cerebrospinal Fluid Leakage
Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery
The purpose of this study is to specifically evaluate the effectiveness of PuraGel, a RADA16 polypeptide hydrogel, in expediting post-operative healing and re-mucosalization of the nasoseptal flap harvest site during endoscopic…
- Conditions
- Skull Base Neoplasms, Cerebrospinal Fluid Leakage, Nasal; Hypertrophy, Mucous Membrane (Septum)
- Trial name
- NCT05898074
- Testing
- Non-Absorbable Packing (Silastic Splint), PuraGel (RADA16) Hydrogel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Postoperative Wound Infection
Evaluation of the Effect of Preoperative Symbiotic Bowel Conditioning on Surgical Site Infection After Elective Colorectal Surgery
The objective of the study is to investigate whether peri-operative symbiotic treatment could reduce the risk of postoperative infections in patients undergoing elective colorectal surgery.
- Trial name
- NCT01413659
- Testing
- Symbiotic
- Volunteers
- 150 people
- Sponsor
- Mashhad University of Medical Sciences
Anterior Cruciate Ligament Injuries, ACL
Laval University Rouge et or Post ACL Surgery Program Effectiveness
The main objective is to compare the effectiveness of two readaptation programs post anterior cruciate ligament surgery. Laval University Rouge et or program is to be compared with the intervention guide from the CHU.
- Trial name
- NCT04137003
- Testing
- Rouge et Or Program, CHU intervention guide
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Chemical Rectus Sheath Block, Chronic Pain
Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries
The aim of this study is to evaluate peri-operative analgesia efficacy of ultrasound guided transversalis fascia plane block in cancer patients undergoing inguinal lymph node dissection
- Conditions
- Chemical Rectus Sheath Block, Chronic Pain, Abdominal Midline Incision, Cancer Surgeries
- Trial name
- NCT07855380
- Testing
- Saline 0.9%, Transversalis fascia plane block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Surgery--Complications, Tibia Fracture
Immediate Mobilization After Plate Osteosynthesis of Proximal Tibial Fractures - A Cohort Study
The purpose of this study is to investigate if immediate mobilization with weight bearing as tolerated following surgery with plates and screws after a fracture of the shinbone near the knee is possible without increased risk.
- Conditions
- Surgery--Complications, Tibia Fracture, Early Ambulation
- Trial name
- IMOP (NCT03314623)
- Testing
- Weight bearing as tolerated
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Slagelse Hospital
Surgical Site Infection, Length of Stay
Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy
Post-operative wound complications in abdominal surgery have a major impact on patient outcomes and the real impact of Closed incision negative pressure therapy (CINVt) is not clear in the literature moreover concerning its…
- Conditions
- Surgical Site Infection, Length of Stay, Seroma, Hematoma
- Trial name
- CiPNT/SSI (NCT04496180)
- Testing
- Closed incision negative pressure therapy versus standard dressing after emergency abdominal laparotomies
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Posttraumatic Stress Disorder
Compassion Meditation for PTSD
The goal of this project is to refine an existing compassion meditation protocol for individuals with posttraumatic stress disorder (PTSD), to examine the safety and feasibility of this approach and to collect data to make…
- Trial name
- NCT02372396
- Testing
- Compassion Meditation (CM), Relaxation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Veterans Medical Research Foundation
Surgical Site Infection (SSI)
Effect of Early vs Late Water Exposure After Cutaneous Surgery
This randomized controlled trial aims to compare the effect of early versus delayed water exposure after cutaneous surgeries on the incidence of surgical site infections.
- Trial name
- NCT07580274
- Testing
- Care as usual
- Volunteers
- 82 people
- Sponsor
- Pak Emirates Military Hospital
Infection, Surgical Site
Negative Pressure Therapy After Infected Mesh Removal.
Chronic mesh infection mesh is a complication with leads to a long hospital stays, reoperation and admissions through emergency department.
- Trial name
- ICROMA (NCT05247086)
- Testing
- Negative pressure therapy
- Volunteers
- 94 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
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