Clinical trials: Post Surgical Wound
Abdominal Cancer
The Analgesic Efficacy of Ultrasound Guided Transversus Abdominal Plane Block After Abdominal Cancer Surgeries
Effective postoperative pain control results in decreased cardiac and pulmonary complications, patient satisfaction and early mobilization.
- Trial name
- TAP (NCT03165383)
- Testing
- Bupivacaine (Transversus Abdominis Plane Block), Intravenous Patient Controlled Analgesia (PCA) Morphine
- Volunteers
- 60 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Ankle Disease, Ankle Injuries
Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Effect of Perineural Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries, Foot Injury, Foot Diseases
- Trial name
- NCT06086418
- Testing
- 0.9 % Sodium Chloride, 0.1mg/kg Dexamethasone, 0.05mg/kg Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Hip Fracture, Blood Loss
Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures
Hip fractures are associated with a large hidden blood loss. That is, the total blood loss associated with hip fracture surgery is much greater than that observed intra operatively.
- Trial name
- NCT02297061
- Testing
- Thrombelastography analysis (TEG)
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Hvidovre University Hospital
Wound Heal
Vacuum Sealing Drainage (VSD) in Promoting Wound Healing and Reducing Complications in Post-Infected Obstetric and Gynecological Surgical Sites
This study aims to evaluate the efficacy of VSD in promoting wound healing and reducing complications, such as re-infection, prolonged hospitalization, and need for further surgical interventions, in obstetric and gynecological…
- Trial name
- NCT07525674
- Testing
- Conventional Wound Care Group, Vacuum Sealing Drainage (VSD) Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Systemic Inflammatory Response Syndrome (SIRS), Postoperative Vasodilation Syndrome
Prediction of Inflammatory Response and Hypotensive Syndrome After Cardiac Surgery by Preoperative Copeptin Level
The purpose of this study is to find a preoperative biomarker before cardiac surgery with cardiopulmonary bypass related to severe postoperative inflammatory response and circulatory complications.
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Postoperative Vasodilation Syndrome, Stress Response, Cardiac Surgery Prognosis
- Trial name
- MicorSIRS (NCT03288610)
- Testing
- Preoperative copeptin level
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Primary Osteoarthritis, Post-traumatic Osteoarthritis of Hip Nos
Observational Study Evaluating Outcomes of Hip Arthroplasty Using Tornier Dual Mobility Acetabular Cup
The purpose of this study is to demonstrate the performance and reliability of Tornier "Dual Mobility Cup" used during primary total hip replacement or hip replacement revision surgery at least 24 months post-insertion.
- Conditions
- Primary Osteoarthritis, Post-traumatic Osteoarthritis of Hip Nos, Femur Head Necrosis, Femur Neck Fracture
- Trial name
- NCT02062450
- Testing
- Primary surgery with Dual Mobility Cup, Revision surgery with Dual Mobility Cup
- Volunteers
- 379 people
- Sponsor
- Stryker Trauma and Extremities
Fluid Balance, Input and Output
Fluid Balance and Clinical Outcomes
This study is about investigating the relationship of postoperative fluid balance, inflammation and acute kidney injury. This is a non-interventional study (no drug administration).
- Conditions
- Fluid Balance, Input and Output, Inflammatory Mediators, Acute Kidney Injury
- Trial name
- NCT01168583
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Florida
Thrombus, Embolus
A PMCF Study Confirm the Performance and Safety of the TufTex Over-the-Wire (OTW) Embolectomy Catheters
A PMCF study to confirm the performance and safety of the LeMaitre® TufTex Over-the-Wire Embolectomy Catheter
- Conditions
- Thrombus, Embolus, Occlusion; Vessel
- Trial name
- OTW (NCT05386342)
- Testing
- TufTex Over-the-Wire Embolectomy Catheter
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 112 people
- Sponsor
- LeMaitre Vascular
Combat Related Symptoms, Combat Trauma
DRONE-WOUND Study: Severe Infection After Drone-Related Combat Trauma
Drone-related combat injuries have become one of the most devastating mechanisms of injury in modern warfare. These injuries often cause extensive tissue devitalization, contamination, open fractures, vascular injuries, and…
- Conditions
- Combat Related Symptoms, Combat Trauma, Infection, Infection Complication
- Trial name
- DRONE-WOUND (NCT07706608)
- Where
- Ukraine
- Volunteers
- 500 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Surgical Site Infection
Effect of a Combination of Bundles on Surgical-site Infection After Elective Colorectal Surgery
A prospective randomized clinical trial will be performed. Patients will be randomized in 2 groups. The experimental group will undergo the combined application of intraperitoneal irrigation with clindamycin and gentamicin…
- Trial name
- NCT03081962
- Testing
- Bundle, Standard care
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospital General Universitario Elche
Hip Fracture, Elderly Patients
Hope Theory-Based Nursing Intervention After Hip Fracture Surgery
This is a randomized controlled trial to evaluate the effectiveness of a Snyder Hope Theory-based nursing intervention on elderly patients following hip fracture surgery.
- Conditions
- Hip Fracture, Elderly Patients, Postoperative Recovery, Nursing Interventions
- Trial name
- NCT07400770
- Testing
- Snyder Hope Theory-based Nursing Intervention, Standard Postoperative Care
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Institute of Orthopaedic Surgery, Taizhou No.3 People's Hospital
Post-Surgical Complication, Periodontal Inflammation
Analysis of Early Healing of Sutures in Periodontal Surgery
The main objective is to analyze post-surgical periodontal healing after conventional periodontal surgery where an absorbable suture coated with clorhexidine (Novosyn Clorhexidine) versus conventional sutures without…
- Conditions
- Post-Surgical Complication, Periodontal Inflammation, Surgical Site Infection
- Trial name
- Sutures (NCT06201377)
- Testing
- Periodontal Access Surgery+ Suture with chlorhexidine, Periodontal Access Surgery+ Suture without chlorhexidine
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ana María García de la Fuente
Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD)
Assessment of Plasma and NGAL for the Early Prediction of Acute Kidney Injury After Cardiac Surgery in Adults Study
The study aims to recruit 156 (54 Acute Kidney Injury (AKI);102 non-AKI) patients undergoing Cardio pulmonary bypass (CPB) surgery, including those with Chronic Kidney Disease (CKD) and multiple co-morbidities.
- Conditions
- Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD), End Stage Renal Disease (ESRD), Estimated Glomerular Filtration Rate (eGFR)
- Trial name
- NGAL (NCT02733328)
- Testing
- CPB Surgery
- Where
- United Kingdom
- Volunteers
- 405 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Shock, Septic, Hyperlactatemia
Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery
The MostCare system, thanks to the Pressure Recording Analytical Method (PRAM; Vygon, Padua, Italy), provides new hemodynamic parameters of the cardiovascular system.
- Conditions
- Shock, Septic, Hyperlactatemia, Oliguria, Aortic Aneurysm, Abdominal
- Trial name
- RELASTANCE (NCT04388267)
- Testing
- Fluid challenge
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Central Hospital, Nancy, France
Acute Renal Failure
Brief Title:Effect of a Preoperative Calorie Restriction on Renal Function After Cardiac Surgery
The aim of this study is to assess the effect of a diet prior to cardiac surgery on the common postoperative decline of renal function. Until now, there is no known drug or procedure to preserve the kidneys from this impairment.
- Trial name
- CR_KCH (NCT01534364)
- Testing
- calorie restriction
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University of Cologne
Pain Management, Postoperative Pain
Psilocybin After Trauma Surgery for Pain
The goal of this clinical trial is to evaluate whether a single dose of psilocybin is feasible and safe for adults with opioid use disorder (OUD) who are recovering from trauma surgery.
- Trial name
- NCT07406828
- Testing
- Psilocybin (Usona Institute), Postoperative analgesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Trent Emerick
Wound Healing After MMS Surgery, BCC - Basal Cell Carcinoma
Effectiveness and Safety of X A-DERM™ Microsurfaced Acellular Dermal Matrix for Wound Healing After MOHS Surgery
The goal of this single-arm clinical trial is to learn about the effectiveness and safety of the X A-DERM™ mADM in promoting wound healing and improving scar formation after MMS surgery for removing BCC, SCC, or MIS lesions on…
- Conditions
- Wound Healing After MMS Surgery, BCC - Basal Cell Carcinoma, SCC - Squamous Cell Carcinoma, Melanoma In Situ
- Trial name
- NCT06919809
- Testing
- A microsurfaced ADM (acellular dermal matrix)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- McGuire Institute
Anterior Talofibular Ligament Injury
To Evaluate the Effectiveness of the Use of a Novel Crosslinking Hyaluronan Hydrogel on the Prevention of the Adhesion Occurrence After Anterior Talofibular Ligament Repair Surgery
The goal of this clinical trial is to evaluate the effectiveness of the use of a novel crosslinking hyaluronan hydrogel on the prevention of the adhesion occurrence after anterior talofibular ligament repair surgery.
- Trial name
- NCT06826898
- Testing
- DEFEHERE Absorbable Adhesion Barrier
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Talent Cro Inc.
Cataract, Surgical Injury
Eye Surface Properties After Using Dexamethasone Drops With and Without Preservatives in Patients After Cataract Surgery
The goal of this interventional, real world data study is to evaluate the impact of preservatives on the post-cataract ocular surface. The main question is to learn about an effect of preservatives on the eye surface.
- Conditions
- Cataract, Surgical Injury, Healing Wound
- Trial name
- EyeSurface (NCT05753787)
- Testing
- preservative-free solution of standard post-cataract eye drops
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Spektrum Center of Clinical Ophthalmology
Acute Kidney Injury
Preoperative Level of Hemoglobin A1c and Acute Kindey Injury After Coronary Artery Bypass Grafting Surgery
Background: The development of acute kidney injury (AKI) is an important indicator of clinical outcomes after cardiac surgery. Elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients…
- Trial name
- NCT05390281
- Testing
- increase in serum creatinine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
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