Clinical trials: Post Surgical Wound
Pediatric Traumatic Brain Injury
Extradural Hematoma in Pediatrics After Acute Head Injury: Surgical and Clinical Outcome
Acute extradural hematoma (EDH) is a potentially life-threatening neurosurgical emergency in children, commonly resulting from traumatic head injury.
- Trial name
- NCT07696598
- Testing
- evacuation of hematoma
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Critical Illness, Malnutrition
RCT: Early Feeding After PEG Placement
Randomized controlled trial to establish evidence on which to base timing of enteral feeding after bedside PEG placement in ventilated Trauma and Surgical ICU patients.
- Conditions
- Critical Illness, Malnutrition, Gastrostomy, Procedural Sequelae
- Trial name
- PEG (NCT04110613)
- Testing
- noFast: Start tube feeds within 1 hour of procedure
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Carilion Clinic
Acute Kidney Injury, Coronary Artery Disease
Renal Doppler Indices for Predicting Acute Kidney Injury After Isolated CABG
Acute kidney injury can occur after coronary artery bypass grafting (CABG). This prospective, single-center observational study will evaluate whether two measurements obtained from renal Doppler ultrasound-the renal augmented…
- Trial name
- NCT07821983
- Testing
- Renal Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Antisepsis
Effect of Skin Antisepsis After Skin Closure on Wound Infection After Abdominal Surgery for Sepsis: a Preliminary Report
The benefits of pre-incision skin antisepsis is well established. However, the role of skin antisepsis after skin closure in abdominal surgery for sepsis is not well reported.
- Trial name
- NCT05896462
- Testing
- 10% povidone iodine
- Where
- Nigeria
- Volunteers
- 37 people
- Sponsor
- Ikechukwu Bartholomew Ulasi
Early Mobilization, Elbow Stiffnes
Early Mobilisation After Surgery in Patients With Elbow Fracture-dislocation
The purpose with the study is to evalute if early mobilsation after surgery in patients vid elbow frakture-dislocation may lead to better armfunction and reduce common complications as stiffnes in the elbow.
- Conditions
- Early Mobilization, Elbow Stiffnes, Elbow Fracture
- Trial name
- NCT04648488
- Testing
- Experimental early mobilisation, Aktive comparator standrad treatmnet
- Volunteers
- 60 people
- Sponsor
- Region Östergötland
Cardio-pulmonary Bypass, Cardiovascular Surgery
Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After Cardiovascular Surgery
Neurologic Dysfunction is one of the main factors contributing to poor outcomes in cardiac surgery patients, except for heart failure.
- Conditions
- Cardio-pulmonary Bypass, Cardiovascular Surgery, Cerebral Protection, Brain Injury
- Trial name
- NCT06723366
- Testing
- Angong Niuhuang Pill (ANP), Control (Standard treatment)
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Nanjing Medical University
Post-Op Complication, Spine Surgery
Irrisept Solution for Instrumented Spine Surgery
Various spine surgeons perform wound irrigation using saline mixed with vancomycin, relying on mechanical debridement of non-viable tissue, physical disruption of biofilm, and bacteriostatic effect against gram positive flora.
- Conditions
- Post-Op Complication, Spine Surgery, Site Infection, Surgical Site Infection
- Trial name
- NCT06439953
- Testing
- Chlorhexidine gluconate solution, Vancomycin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rhode Island Hospital
ACL - Anterior Cruciate Ligament Rupture
Assessment of Electromyographic Activity in the Quadriceps and Hamstrings of the Operated Limb Versus the Unaffected Limb in Patients Who Have Undergone ACL Surgery, With and Without Post-operative AMI - an Exploratory Study
Traumatic injuries to the knee joint, such as an anterior cruciate ligament tear, can compromise the ability of the muscle at the front of your thigh-known as the quadriceps-to contract voluntarily, despite the anatomical…
- Trial name
- AMIMYO (NCT07659561)
- Testing
- Electromyography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Myocardial Injury After Noncardiac Surgery (MINS), Myocardial Ischemia
Ivabradine for Prevention of Myocardial Injury After Noncardiac Surgery Trial (PREVENT-MINS)
This study is a multicentre, randomized controlled trial of ivabradine versus placebo.
- Trial name
- PREVENT-MINS (NCT05279651)
- Testing
- Ivabradine
- Where
- 26 sites in Poland
- Volunteers
- 2,146 people
- Sponsor
- Jagiellonian University
AKI - Acute Kidney Injury, Cardiac Surgery Associated - Acute Kidney Injury
Post-Marketing Study to Assess the Safety & Efficacy of RenalGuard® Therapy for Prevention CSA-AKI
The goal of this clinical trial is to assess the effect of RenalGuard Therapy in reducing the rates of Acute Kidney Injury (AKI) within 72 hours after cardiac surgery in patients at risk of developing Cardiac Surgery Associated…
- Trial name
- KIDNEY-II (NCT06811805)
- Testing
- RenalGuard Therapy, Standard of Care (SOC)
- Where
- 8 sites in Belgium, Germany and 3 more
- Volunteers
- 300 people
- Sponsor
- CardioRenal Systems, Inc.
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Hepatectomy
Efficacy of Local Anesthesic on Diaphragmatic Function After Upper Abdominal Surgery
Upper abdominal surgery is known to induce such pulmonary complications as pneumonia, atelectasis, pleural effusion. The post operative diaphragmatic dysfunction participates to these complications and lasts for 7 days after…
- Trial name
- CATPAR (NCT02353702)
- Testing
- Sniff test, Infusion of Ropivacaine during 48 hours, Continuous parietal infusion with parietal catheter
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Rouen
Atrial Fibrillation, Ventricular Arrythmias
Effect of Remote Ischemic Preconditioning on Cardiac Function After Cardiac Surgery
The purpose of this study is to evaluate the effects of Remote Ischemic Preconditioning on cardiac function in patients undergoing cardiac surgery compared to control intervention.
- Conditions
- Atrial Fibrillation, Ventricular Arrythmias, Myocardial Injury, Cardiac Function
- Trial name
- NCT00882622
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Germany
- Sponsor
- Patrick Meybohm
Diabetic Ulcers, Venous Leg Ulcer
PMCF Study of Debridement Pad
The design of the study is a clinical trial of Debridement Pad in subjects with superficial, chronic and acute wounds consisting of Diabetic ulcers, Arterial and Venous Leg ulcers, Pressure ulcers, Postoperative wounds healing by…
- Conditions
- Diabetic Ulcers, Venous Leg Ulcer, Arterial Leg Ulcer, Pressure Ulcer
- Trial name
- NCT07255937
- Testing
- Debridement Pad
- Where
- Spain
- Volunteers
- 184 people
- Sponsor
- Advanced Medical Solutions Ltd.
Cardiac Surgical Procedures, Hemodynamics
Structured Hemodynamic Assessment to Guide Care After Cardiac Surgery
This multicenter pilot randomized controlled trial will evaluate whether providing treating physicians with a structured hemodynamic assessment influences care after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures, Hemodynamics, Fluid Therapy, Acute Kidney Injury
- Trial name
- UTF-in-CVICU (NCT07792707)
- Testing
- Expert Report of a Structured Hemodynamic Assessment, Standard Care (in control arm)
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Spine Injury, Trauma
Spine Trauma in the Elderly
Our study aims at investigating short and long-term outcomes following surgery for subaxial spine injuries in the elderly (octogenarian) population.
- Conditions
- Spine Injury, Trauma, Surgery
- Trial name
- NCT06019572
- Testing
- Spine decompression and fixation surgery
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Karolinska Institutet
Post-traumatic Stress Disorder
Adjunctive Biofeedback Intervention for Operation Iraqi Freedom/Operation Enduring Freedom (OIF-OEF) Post Traumatic Stress Disorder (PTSD)
Objective: The aims are to examine the feasibility and acceptability of a handheld biofeedback device as an adjunct treatment for Post Traumatic Stress Disorder (PTSD) and to estimate its clinical effect size.
- Trial name
- ABIOP (NCT00920036)
- Testing
- StressEraser
- Volunteers
- 8 people
- Sponsor
- Central Arkansas Veterans Healthcare System
Surgery, Trauma to the Abdomen
Non Invasive Ventilation in Abdominal Postoperative Period
Acute respiratory failure may occur early in the postoperative course, requiring endotracheal intubation and mechanical ventilation in selected patients, thus increasing morbidity and mortality and prolonging intensive care unit…
- Conditions
- Surgery, Trauma to the Abdomen, Acute Respiratory Failure
- Trial name
- NIVAS (NCT01971892)
- Testing
- Non Invasive ventilation (facial mask and NIV ventilator), Standard oxygen therapy with facial mask
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Appendicitis
Wound Infection Alexis Wound Retractor
The purpose of this study is to determine whether the incidence of surgical site wound infection will be reduced in open appendectomy patients through the use of the Alexis® wound retractor.
- Trial name
- NCT00323453
- Testing
- Open appendectomy using Alexis Wound Retractor followed by standardized wound closure, Open appendectomy with standardized wound closure
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Santa Barbara Cottage Hospital
Liver Transplantation (LT)
Intraoperative Glycemic Variability and Infectious Complications After Liver Transplantation
This study aims to evaluate whether intraoperative glycemic variability (GV) is independently associated with the risk of infectious complications within 30 days after elective liver transplantation.
- Trial name
- SUGAR-LT (NCT07786857)
- Where
- Poland
- Volunteers
- 240 people
- Sponsor
- Medical University of Warsaw
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