Clinical trials: Post Surgical Wound
Knee Injuries, Pain, Postoperative
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
The purpose of this study is to look at pain management with opioids versus non-opioids after knee arthroscopy. This study will determine 1) whether the most commonly used non-narcotic medications provide pain relief comparable…
- Conditions
- Knee Injuries, Pain, Postoperative, Opioid Use
- Trial name
- NCT03858231
- Testing
- Norco 5Mg-325Mg Tablet, Ibuprofen 600 mg, Acetaminophen 325Mg Tab
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Sanford Health
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Nerve Injury, Pain Management
Study of Nerve Injuries and Physical Exercise
This study will explore if combining exercise with sensory training can help improve sensory function and reduce pain after an injury to the nerves in the arm and hand.
- Conditions
- Nerve Injury, Pain Management, Sensorial Disturbance
- Trial name
- SNIPE (NCT06846788)
- Testing
- Physical exercise
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Karolinska Institutet
Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer
The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients
The investigators want to study whether the use of painting art therapy has an influence on the quality of life, the complication rate and the general outcome of major abdominal surgery.
- Conditions
- Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer, Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT04524260
- Testing
- perioperative painting art therapy (LOM® solution centered art therapy), perioperative painting art therapy (LOM® solution centered art therapy) - control
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Cartilage Lesion
A Talus Implant in Patients Between 20-60 Years of Age Followed up for a Minimum of 2 Years After Surgery
The project will investigate safety, feasibility and efficiency when using Episurf Episeal talus implant in patients with osteochondral ankle injuries.
- Trial name
- NCT06932380
- Testing
- Talus prosthesis
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Vestre Viken Hospital Trust
Acute Kidney Injuries, Kidney Injuries, Acute
Short Term Spironolactone for Prevention of Acute Kidney Injury After Cardiac Surgery
Our aim is to test whether short term perioperative administration of oral spironolactone could reduce incidence of postoperative acute kidney injury (AKI) in cardiac surgical patients.
- Conditions
- Acute Kidney Injuries, Kidney Injuries, Acute, Kidney Injury, Acute, Acute Renal Injury
- Trial name
- NCT02417896
- Testing
- Spironolactone
- Where
- 2 sites in Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Acute Kidney Injury
Changes in Gene Expression and Prognosis of Blood Immune Cells After Cardiopulmonary Bypass Surgery
The goal of this observational study is to learn about the changes in gene expression in blood immune cells in after cardiac surgery with cardiopulmonary bypass.The main question it aims to answer is: What specific gene…
- Trial name
- NCT05871203
- Testing
- Gene sequencing
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Transversalis Fascia Plane Block, Gynecologic Surgical Procedures
Efficacy of US-guided TFPB in Open Gynecologic Surgery
Transversalis fascia plane block (TFPB) has been studied and has shown to be very effective in controlling postoperative pain after caesarean section but has not been studied in open gynecologic surgery with transverse incision.
- Trial name
- NCT06847022
- Testing
- US-guided transversalis fascia plane block
- Where
- Thailand
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Flexor Tendon Injury
Virtual Reality Combined With Active Mobilization Post Flexor Tendon Repair
The purpose of this study is to evaluate the efficacy of combining IVR-based rehabilitation with a controlled early active mobilization protocol on functional outcomes, digit range of motion, grip strength, pinch strength and…
- Trial name
- NCT07875452
- Testing
- active mobilization, active mobilization plus IVR-based rehabilitation.
- Where
- 2 sites in Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Ankle Fractures
The Therapeutic Effect of Dau-Di-Wu-Gong in Patient With Ankle Fracture
Ankle fracture is one of most common bone fracture in Taiwan, although ankle fracture can be treated by surgical operation, local edema, pain and wound poor healing always is noted, according to the investigator's knowledge, no…
- Trial name
- NCT03805347
- Testing
- Helminthostachys zeylanica(L.)Hook, Starch
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Changhua Christian Hospital
Oral Cancer
Defining Mechanisms of Surgical Site Infection After Oral Cancer Surgery
The study design is an observational cohort study of patients undergoing standard of care oral cavity reconstruction. An observational study is required to prospectively evaluate microbial and antibiotic mechanisms underlying…
- Trial name
- NCT06681935
- Testing
- Oral Cavity Reconstruction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Wound Healing, Acute Skin Wounds
Study of LUT017 Gel to Improve Healing of Skin Wounds After Removal of Benign Lesions in Healthy Adults
This is a Phase 1 research study evaluating the safety and potential benefits of a topical gel called LUT017 in helping skin wounds heal after minor skin procedures.
- Trial name
- NCT07463378
- Testing
- LUT017,Topical BRAF inhibitor
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Antoni Ribas
Post-surgical Oral Wounds, Oral Cavity Surgery
Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity.
The PR-DENT study is an interventional, single-center, controlled clinical investigation aimed at evaluating the clinical performance and safety of a Class III medical device based on linear hyaluronic acid for the treatment of…
- Conditions
- Post-surgical Oral Wounds, Oral Cavity Surgery, Wound Healing/Regeneration, Dental Extraction Sites
- Trial name
- PR-DENT (NCT07421934)
- Testing
- Intervention: Linear Hyaluronic Acid (Gumblast), Control: Standard Surgical Procedure
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- The Wave Innovation Group s.r.l.
Peripheral Nerve Injury
Enhancement of Functional Recovery After Peripheral Nerve Injury With Tacrolimus
Tacrolimus (FK506) is an immunosuppressive medication that promotes organ allograft survival. It has also been shown to enhance nerve regeneration and muscle reinnervation in animals but these properties have not previously been…
- Trial name
- NCT00950391
- Testing
- Tacrolimus
- Sponsor
- Washington University School of Medicine
Kidney Failure, Acute, Acute Kidney Insufficiency
Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery
This study proposes to investigate whether treatment with minocycline pre-operatively in patients with mild to moderate chronic kidney disease undergoing cardiac surgery will reduce the occurence of kidney injury.
- Trial name
- NCT00556491
- Testing
- minocycline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Tarek M. El-Achkar
Burns
Oxycodone (10, 20 mg) in a Postoperative Dressing
The study mainly focuses on pain management using 10- or 20mg oxycodone burn wound dressing at Poznan University of Medical Sciences.
- Trial name
- NCT06142591
- Testing
- Oxycodone 10mg, Oxycodone 20mg
- Volunteers
- 20 people
- Sponsor
- Poznan University of Medical Sciences
Hip Osteoarthritis, Avascular Necrosis
Insignia™ Hip Stem Outcomes Study
The objective of this study is to evaluate the safety and effectiveness of the Insignia™ Hip Stem for global market access and post-market clinical follow-up up to 10 years postoperative.
- Conditions
- Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
- Trial name
- NCT05144191
- Testing
- Insignia uncemented Hip Stem
- Where
- 11 sites in United States
- Volunteers
- 313 people
- Sponsor
- Stryker Orthopaedics
Surgery--Complications, Cardiac Valve Disease
Prevention of Acute Kidney Injury by N-Acetylcystein in Patients Undergone Cardiac Valve Replacement
This is a randomized clinical trial, double-blind, placebo-controlled study with the goal to assess the influence of using N-AcetylCysteyn (NAC) for prevention of AKI (Acute Kidney Injury) in post operatory of valve replacement…
- Conditions
- Surgery--Complications, Cardiac Valve Disease, Acute Kidney Injury, Oxygen Radical Damage
- Trial name
- NCT03440268
- Testing
- N Acetyl Cysteine
- Where
- Brazil
- Volunteers
- 154 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetic Foot Ulcer, Pressure Injury
A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System
The purpose of this study is to determine if use of the Medela Invia Motion NPWT system supports acceptable progress towards the goal of therapy when treating patients with a variety of wound types during the evaluation period.
- Conditions
- Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound
- Trial name
- NCT04593693
- Testing
- Invia Motion Endure NPWT system
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medela AG
Atrial Fibrillation
ALDOsterone for Prediction of Post-Operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is a major and frequent complication occurring after cardiac surgery, contributing to prolonged intensive care and hospital stays and is associated with several cardiovascular…
- Trial name
- ALDO-POAF (NCT02814903)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
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