Clinical trials: Post Surgical Wound
Myocardial Injury After Non-cardiac Surgery, Urologic Cancer
Prediction of Myocardial Injury After Non-Cardiac Surgery in Urologic Cancer Patients
This prospective multicenter observational study aims to evaluate the predictive value of artificial intelligence-based analysis of preoperative 12-lead electrocardiography for myocardial injury after non-cardiac surgery (MINS)…
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Urologic Cancer, Major Adverse Cardiovascular Events (MACE)
- Trial name
- URO-MINS (NCT07634666)
- Testing
- No intervention assigned
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Korea University Anam Hospital
Complication of Coronary Artery Bypass Graft, Surgical Wound Infection
Effectiveness of Triclosan Coated Sutures in Preventing Leg Wound Infection After Coronary Artery Bypass Surgery
The purpose of this study is to assess whether triclosan-coated sutures reduces wound infections compared to regular non-coated sutures, after saphenous vein harvesting in CABG patients.
- Trial name
- NCT01457859
- Testing
- Triclosan, Conventional non-coated surgical sutures
- Where
- Israel
- Volunteers
- 410 people
- Sponsor
- Rambam Health Care Campus
Surgical Site Infection; Cardiac Surgery; Advanced Dressing; Postoperative Care
Does Occlusive Hydrocolloid Silver-containing Wound Dressing After Sternotomy Reduce Surgical Side Infection After Cardiac Surgery?
Wound healing disorders are a major problem in cardiac surgery. They prolong the inpatient stay and are associated with a high health and, above all, psychological burden for patients.
- Trial name
- OHSCWD (NCT06508879)
- Testing
- Aquacel Ag Surgical®, Standard Care (sterile gauze and adhesive tape)
- Where
- Germany
- Volunteers
- 352 people
- Sponsor
- University Medical Center Mainz
Healthy, Inflammation
Etanercept (Enbrel) to Treat Pain and Swelling After Third Molar Extraction
This study will evaluate the effects of the anti-inflammatory drug etanercept (Enbrel) on relieving pain and swelling after oral surgery.
- Trial name
- NCT00006070
- Testing
- etanercept (Enbrel)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Frozen Shoulder, Rotator Cuff Tears
Preoperative Psychological Risk Factors for the Retractable Capsulitis of the Shoulder After Shoulder Rotator Cuff Repair Surgery
The main objective of our study is to determine whether preoperative anxiety, depression and kinesiophobia are risk factors for retractile capsulitis after arthroscopic rotator cuff repair to best support these patients.
- Trial name
- NCT04044196
- Testing
- Rotator cuff repair
- Where
- 2 sites in France
- Volunteers
- 77 people
- Sponsor
- Hospital Ambroise Paré Paris
Surgical Incision
A Comparison Between Two Post-operative Dressings
Surgical site infections are one of the leading causes of post-operative morbidity and mortality worldwide. The ideal post-operative dressing is impermeable and remains intact preventing contamination of the incision with…
- Trial name
- DrySee (NCT04888624)
- Testing
- DrySee® dressing with moisture detection, Tegaderm® + Pad transparent film dressing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SerenaGroup, Inc.
Acute Abdomen, Abdominal Trauma
Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Emergency Laparotomy
The goal of this clinical trial is to test the safety and effectiveness of the ERAS protocols compared to a conventional care protocols in patients who received emergency laparotomy.
- Conditions
- Acute Abdomen, Abdominal Trauma, Emergency Surgery
- Trial name
- ERAS (NCT06182488)
- Testing
- ERAS protocols, Conventional protocols
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University
Surgical Site Infection
Surgical Site Infection After Episiotomy Repair Related to Routine Use of Antibiotic Prophylaxis in Low-Risk Population
Bacterial infections occurring during labor, childbirth, and the puerperium may be associated with considerable maternal and perinatal morbidity and mortality.
- Trial name
- NCT06154720
- Testing
- Antibiotics
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Impaired Wound Healing, Factor XIII Deficiency
Wound Healing Abnormalities in Major Abdominal Surgery
This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery.
- Trial name
- INWOUND (NCT00735579)
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Klinikum St. Georg gGmbH
Pertrochanteric Fracture
Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery
This is a phase I, randomized, single-blind, placebo-controlled, single-center study of the effects of surgical site injection on pain and narcotic utilization in participants who undergo surgery for lower extremity fractures.
- Trial name
- NCT03693404
- Testing
- Marcaine, Duramorph , ketorolac, Bupivacaine (Marcaine), General Anesthetics
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- NYU Langone Health
Colorectal Cancer, Neoadjuvant Chemotherapy
Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer
Colorectal cancer is the fourth most common cancer in China. Up to 30% of patients with colorectal cancer present with an emergency obstruction of the large bowel at the time of diagnosis, and 70% of all malignant obstruction…
- Conditions
- Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction
- Trial name
- NACSOC (NCT02972541)
- Testing
- Stenting with neoadjuvant chemotherapy, Stenting with immediate Surgery
- Where
- 32 sites in China
- Volunteers
- 248 people
- Sponsor
- Beijing Chao Yang Hospital
Infections, Surgery
Study Looking at the Effect of Silverlon on Post Operative Wound Infections
This clinical study is a prospective, randomized, controlled trial of patients undergoing elective colorectal surgical procedures that receive an abdominal skin incision of at least 6 cm.
- Trial name
- NCT01143883
- Testing
- Silverlon, Standard of Care Dressing
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Jorge Marcet
Acute Kidney Injury
Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery
This is a prospective randomized clinical trial designed to determine the effect of intraoperative dexmedetomidine administration on renal function after coronary artery bypass graft surgery.
- Trial name
- NCT06378827
- Testing
- Dexmedetomidine
- Where
- Serbia
- Volunteers
- 100 people
- Sponsor
- University of Novi Sad
Child Health, Bypass Graft Occlusion
Long-term Outcome in Pediatric Surgical Bypass Grafting After Traumatic Injury and Tumor Resection
Introduction: Vascular bypass surgery in children differs significantly from adults. It is a rarely performed procedure in the setting of trauma and tumor surgery to facilitate limb salvage.
- Trial name
- NCT04455373
- Testing
- pediatric vascular bypass grafting
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Acute Kidney Injury
Early Prediction of Acute Kidney Injury in High Risk Patients After Non-cardiac Surgery
Acute kidney injury (AKI) is a common complication after non-cardiac surgery with adverse short and long term morbidity and mortality.
- Trial name
- NCT03880110
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University First Hospital
Head and Neck Cancer
Pre- and Postoperative Nutrition in Head and Neck Cancer Patients
The purpose of the project is to investigate the effect of wound healing of a combined pre- and postoperative oral supplement, consisting of zinc, vitamin C, arginine and multivitamin, as a supplement for adequate nutrition in…
- Trial name
- NCT03531190
- Testing
- Nutritional supplement (Protein + MIX), Nutritional supplement (Protein)
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Copenhagen
Acute Renal Failure, Acute Kidney Injury
Pre-operative Short-term Administration of a Formula Diet Containing a Non-milk-derived Protein Source for Prevention of Acute Kidney Injury After Cardiac Surgery
Cardiac surgery is associated with a high risk of postoperative AKI with significant morbidity and mortality. To date, no preventive or therapeutic measures exist to prevent this.
- Trial name
- UNICORN (NCT03715868)
- Testing
- Non-milked derived protein source formula diet
- Where
- Germany
- Volunteers
- 117 people
- Sponsor
- University of Cologne
Orthopedic Surgery
Pain Relief After Forefoot Surgery
The aim to test whether continues local anaesthetic infusion via tibial catheter or wound catheter will improve pain relief following forefoot surgery In this sequential prospective randomised, controlled clinical trial,75…
- Trial name
- NCT01019005
- Testing
- Catheter
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust