Clinical trials: Post Surgical Wound
Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients…
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559215
- Testing
- Exparel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Delirium, Postoperative Cognitive Dysfunction
Biomarkers Associated With Postoperative Cognitive Dysfunction
Loss of cognitive function after major surgery is a significant risk in older people. It can occur acutely in the days after surgery as delirium or in months to years later as a persistent reduction in brain function termed…
- Conditions
- Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- NCT05464355
- Testing
- Intraoperative electroencephalography recording, Neurofilament light chain measurement, Tau protein measurement
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Oxford
Acute Kidney Injury, Congenital Cardiac Disorders
Urine Biomarkers to Predict Acute Kidney Injury After Pediatric Cardiac Surgery
The goal of this prospective cohort study is to evaluate, in pediatric patients after cardiac surgery, the predicting capability of biomarkers for acute kidney injury.
- Trial name
- NCT05637424
- Volunteers
- 101 people
- Sponsor
- University Ghent
Chronic Subdural Hematoma
The Finnish Study of Intraoperative Irrigation Versus Drain Alone After Evacuation of Chronic Subdural Hematoma (FINISH)
FINISH-trial is a prospective, randomized, controlled, parallel group non-inferiority trial comparing single burr-hole evacuation of chronic subdural hematoma (CSDH) with intraoperative irrigation (IR) and evacuation of CSDH…
- Trial name
- FINISH (NCT04203550)
- Testing
- Intraoperative irrigation, No irrigation
- Where
- Finland
- Volunteers
- 587 people
- Sponsor
- Helsinki University Central Hospital
Myocardial Injury, Myocardial Infarction
Implementation of a Clinical Screening and Response System for Cardiac Complications After Noncardiac Surgery
The investigators aim to show the feasibility and medicoeconomic impact of implementing a clinical screening and response system for the early detection of perioperative cardiac complications in high-risk patients.
- Conditions
- Myocardial Injury, Myocardial Infarction, Perioperative Complication
- Trial name
- ImplementPMI (NCT05859620)
- Testing
- Patient assessment and follow-up
- Where
- 5 sites in Austria, Switzerland
- Volunteers
- 900 people
- Sponsor
- University Hospital, Basel, Switzerland
Knee Injuries
Knee Nerve Cryoneurolysis and Impact on Pain After Prosthetic Surgery
Interventional, comparative, randomized, controlled study versus standard treatment, in 3 parallel groups, monocentric, aiming to demonstrate the superiority of preoperative cryoneurolysis versus no procedure, in patients…
- Trial name
- Cryogenou (NCT05059535)
- Testing
- standard pain relievers
- Where
- France
- Volunteers
- 52 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Zygomatic and Lefort II Fractures, Infraorbital Rim Fixation
Post-operative Lower Eyelid Massage for Prevention of the Lower Eyelid Scare Contracture After Subciliary Approach
Patients were randomly allocated to the lower eyelid massage (experimental) or standard care (control) groups. The massage group received post-operative instructions.
- Conditions
- Zygomatic and Lefort II Fractures, Infraorbital Rim Fixation, Subciliary Approach Repair
- Trial name
- RCT (NCT06311318)
- Testing
- lower eyelid massage
- Volunteers
- 59 people
- Sponsor
- Chiang Mai University
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps
Patients undergoing free flap reconstructive surgery at University of California, Davis Medical Center (UCDMC) will be assigned randomly into no intervention group (immediate post operative care in an ICU) or intervention group…
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head and Neck Carcinoma, Trauma
- Trial name
- ICU (NCT03340038)
- Testing
- Non-ICU Specialty ward
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of California, Davis
Robotic Surgical Procedure
LONG TERM FOLLOW UP AFTER PEDIATRIC SINGLE SITE ROBOTIC CHOLECYSTECTOMY
Robotic single-site cholecystectomy (RSSC) was first reported in children the PI from GSH in 2015, demonstrating the feasibility, safety, and short learning curve associated with RSSC.
- Trial name
- NCT07383961
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Good Samaritan Hospital Medical Center, New York
Hip Dysplasia
Stress Analysis of Hip Dysplasia
The main objective of this study is to predict cartilage contact pressures in the hip after periacetabular osteotomy (PAO).
- Trial name
- NCT01575977
- Volunteers
- 12 people
- Sponsor
- University of Utah
Pulmonary Atelectasis, Obesity, Morbid
Effects of Individualized PEEP Guided by Driving Pressure on Postoperative Atelectasis in Patients With Morbid Obesity
Atelectasis is a common complication in patients undergoing surgery under general anesthesia, particularly in obese patients. Postoperative atelectasis could last for more than 24h and contribute to a variety of other…
- Trial name
- NCT06181279
- Testing
- Individualized PEEP group, Fixed PEEP group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Yongtao Sun
Periprosthetic Fractures
Investigation on the Surgical Treatment Effect of Periprosthetic Femur Fracture After Hip Arthroplasty
To Investigate the Surgical Treatment effect of Periprosthetic Femur Fracture After Hip Arthroplasty
- Trial name
- NCT03358186
- Testing
- surgically treated periprosthetic femur fracture
- Volunteers
- 155 people
- Sponsor
- Peking University People's Hospital
Sepsis, Lung Injury
Inhalational Versus Intravenous Anesthesia on Postoperative Lung Injury in Septic Patients Undergoing Surgery
This randomized controlled trial will compare the effects of intraoperative inhalational anesthesia versus intravenous anesthesia on postoperative lung injury in septic patients undergoing surgery.
- Trial name
- NCT07601256
- Testing
- Inhalation Anesthesia, intravenous anesthesia
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
Spine Surgery
Trial of Protein Supplement on Vertebral Fusion in Posterior Spine Fusion Surgery
Receiving protein can affect the bone formation and maintenance by providing a structural matrix of the bone, optimizing the level of IGF-1, increasing intestinal calcium absorption, transferring phosphorous, and improving muscle…
- Trial name
- NCT04091841
- Testing
- protein supplement, Carbo Mass
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University
Chronic Subdural Hematoma
Endovascular Embolization of Chronic Subdural Hematomas After Surgery
Chronic subdural hematomas (CSH) are one of the most frequent pathologies in emergency neurosurgical practice. Standard therapy for symptomatic CSH is surgical drainage.
- Trial name
- ENCLOSURE (NCT05220826)
- Testing
- Post surgical embolization of middle meningeal artery with liquid embolic agents (ethylene vinyl alcohol copolymers as Onix, Squid, Phil or Libro)
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Obese
Pre-operative Diet: Effect of Wound Healing After Bariatric Surgery
This study is a randomised control trial comparing the effects of a pre-operative very low calorie diet (VLCD) on wound healing in the morbidly obese patients undergoing bariatric surgery.
- Trial name
- NCT01950052
- Testing
- Diet group 800 Kcal diet
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College Hospital NHS Trust
AKI - Acute Kidney Injury, Delirium, Postoperative
Metabolomics Analysis of Acute Kidney Injury and Delirium After Cardiac Surgery
Clinical evidence suggests that renal injury leads to changes in the structure of the cerebral cortex in patients, suggesting the existence of the renal brain axis.
- Trial name
- NCT06508593
- Testing
- Serum metabolic profile
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Ketamine, Pecs Block, Topical Wound Instillation , Modefied Radical Mastectomy
Comparative Study of Ketamine Added to Bupivacaine in PECS Block Versus Topical Wound Instillation on Post Operative Analgesia in Modified Radical Mastectomy Surgery
Comparative study of ketamine added to bupivacaine in PECS block versus topical wound instillation on post operative analgesia in modified radical mastectomy surgery
- Trial name
- NCT05410158
- Testing
- Ketamine in PECS block versus topical wound instillation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
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