Clinical trials: Post Surgical Wound
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Colorectal Surgery, Wound Infections
REDWIL: Reduction of Wound Infections in Laparoscopic Colon Resections by Wound Protectors
Surgical site infection is common in colorectal surgery leading to increased postoperative pain, longer hospital stay, delayed wound healing and increased re-operation rates.
- Trial name
- REDWIL (NCT01049971)
- Testing
- wound protector, no wound protector
- Where
- Germany
- Volunteers
- 109 people
- Sponsor
- Charite University, Berlin, Germany
Acute Kidney Injury (AKI)
Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery
The incidence of acute kidney injury (AKI) postoperatively has been identified to be 21.6% in adults and 18.3% in hospitalized individuals.
- Trial name
- NCT05068167
- Testing
- Kidney function test
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- South Egypt Cancer Institute
Axillary Hidradenitis Suppurativa
Perforator Flaps for Axillary Hidradenitis Suppurativa
Hidradenitis Suppurativa (HS) is a recurrent inflammatory disease (< 2 episode /6 months) with 1%-4% prevalence in Europe. Suppurating lesions are painful and involve one or more regions (axilla, genitofemoral, perineum, gluteal…
- Trial name
- HS-PAX (NCT03784313)
- Testing
- skin repair by axillary perforator flaps, skin repair by secondary wound healing
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Skin Reaction to Mechanical, Thermal and Radiation Stimuli, Skin Sensitisation
Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days
Incisional dressings aim to prevent contamination of an incisional wound and protect against skin irritation. Surgeons use incisional negative pressure wound therapy (iNPWT) to manage incisional wounds.
- Trial name
- HHiNPWT7DC (NCT05559697)
- Testing
- Sponsor incisional negative pressure wound therapy device and dressing, Standard of Care incisional negative pressure wound therapy system
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- DeRoyal Industries, Inc.
Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure
Serum Phosphatemia Predictive Marker for AKI Diagnosis After Cardiac Surgery
Cardiac surgery associated acute kidney injury is an independent factor of morbidity and mortality . Despite its delayed elevation, serum creatinine (Cr) remains the goal standard to diagnose AKI.
- Conditions
- Cardiac Surgery With Cardiopulmonary Bypass, Complete Serum Phosphorus Measure, Complete Serum Creatinine Measure
- Trial name
- PhosphoIRA (NCT02900313)
- Testing
- cardiac surgery
- Where
- France
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Hypoxemia, Postoperative Complications
Sigh Ventilation on Postoperative Hypoxemia in Cardiac Surgery
Postoperative pulmonary complications (PPCs) remain a frequent event after pump-on cardiac surgery and are mostly characterized by postoperative hypoxemia.These complications are significant contributors to prolonged intensive…
- Conditions
- Hypoxemia, Postoperative Complications, Cardiac Disease, Acute Lung Injury
- Trial name
- NCT06248320
- Testing
- Sigh ventilation
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Zhongda Hospital
Postoperative Myocardial Ischemia
Evaluation of a Model for Post-Anesthesia Troponin Increase and Heart Injury EStimation
This study evaluates the preoperative cardiovascular risk, the intraoperative hemodynamic characteristics and the surgical photo-plethysmographic index of patients undergoing general anesthesia for non-cardiac vascular surgery to…
- Trial name
- EMPATHIES (NCT03375476)
- Testing
- collection of cardiovascular risk scores and intraoperative cardiovascular parameters, cardiac troponin assay, Electrocardiogram
- Where
- Italy
- Volunteers
- 117 people
- Sponsor
- ASST Fatebenefratelli Sacco
Low Back Pain, Cervical Pain
Prospective Study of Post Surgical Continued Spinal Pain Patients
Continued spinal pain following spine surgery is reported in up to 50% of patients. Disability and pain following spine surgery occurs.
- Conditions
- Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder
- Trial name
- NCT05401682
- Testing
- Cox chiropractic care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Breast Cancer
Localization of Intercostal Perforating Vessels Reduces Wound Complications From Nipple Sparing Mastectomy
Approximately 100 women scheduled for NSM will be consented pre-operatively to participate in the study. US will be performed after induction of general anesthesia, prior to surgery using Sonosite™ portable US, 5-12mHz transducer…
- Trial name
- NCT02938390
- Testing
- Ultrasound for localizing intercostal perforating vessels
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Amita Health
Cerebral Palsy, Post-operative Pain
The Post-Operative Pain in Cerebral Palsy (POPPIES) Trial
Cerebral palsy is common. It affects approximately 3 per 1000 children. Hip displacement due to muscle tightness (spasticity) occurs in up to half of the more severely affected children, and many of these children require major…
- Trial name
- POPPIES (NCT01437644)
- Testing
- botulinum toxin intramuscular injection
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Gingival Recession, Localized, Postoperative Morbidity
Palatal Wound Healing After Free Gingival Graft Surgery
This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG)…
- Conditions
- Gingival Recession, Localized, Postoperative Morbidity, Palatal Donor Site Wound Healing
- Trial name
- NCT07409571
- Testing
- kollajen membran (Cytoplast™ RTMFOAM™, Osteogenics Biomedical Inc., Texas, ABD), triamcinolone acetonide
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Post-operative Pain
Comparison of Post-operative Complications of Bone Augmentation at Anterior of Maxilla After Periosteal Releasing Incision With Two Techniques Diode Laser and Scalpel
The aim of this study was to investigate if using lasers instead of scalpel for flap advancement in bone augmentation procedures would reduce post-operative swelling and pain.
- Trial name
- NCT02711501
- Testing
- Laser-assisted surgery., conventional surgery by blade
- Where
- 3 sites in Iran
- Volunteers
- 14 people
- Sponsor
- Tehran University of Medical Sciences
Postpartum Period, Depression
Relationship Between Postpartum Mood Disorders and Delivery Experience
The purpose of this study is to evaluate potential risk factors for developing postpartum depression or posttraumatic stress disorder during the first year postpartum in patients who have no preexisting history of PTSD or PPD.
- Conditions
- Postpartum Period, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NCT03004872
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
Myopia, Myopic Astigmatism
Machine Learning Prediction of 1-Year Refractive Error After SMILE
This retrospective single-center observational study is designed to develop and internally validate a multi-output machine learning model for predicting 1-year postoperative refractive prediction error after small incision…
- Conditions
- Myopia, Myopic Astigmatism, Refractive Error - Myopia Axial
- Trial name
- SMILE (NCT07478419)
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Tongji University
Breast Cancer, Chronic Pain
Can Chronic Post-surgical Pain be Reduced by Preserving Intercostobrachial Nerve During Axillary Lymph Node Dissection? : A Randomized Controlled Trial
Intercostobrachial nerve (ICBN) is a cutaneous nerve that provides sensation to the lateral chest, upper medial arm and axilla. It arises from the second intercostal nerve and leave intercostal space at the level of midaxillary…
- Conditions
- Breast Cancer, Chronic Pain, Intercostobrachial Nerve Injury
- Trial name
- PAINE (NCT05198622)
- Testing
- Intercostobrachial Nerve Preserving Axillary Lymph Node Dissection, Intercostobrachial Nerve Sacrificing Axillary Lymph Node Dissection
- Where
- Pakistan
- Volunteers
- 182 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Postoperative Abdominal Wounds, Wound-healing Impairments
Evaluate the Efficacy of the Treatment of Iatrogenic Subcutaneous Abdominal Wounds (ISAW) After Surgery by Application of Negative Pressure Wound Therapy (NPWT) in Comparison to Standard Conventional Wound Therapy (SCWT) of the Clinical Routine
The purpose of this study is to determine whether Negative Pressure Wound Therapy (NPWT) or Standard Conventional Wound Therapy (SCWT) are effective in the treatment of Iatrogenic Subcutaneous Abdominal Wound healing-impairments…
- Trial name
- ISAW (NCT01611207)
- Testing
- Negative Pressure Wound Therapy, Standard Wound Therapy
- Where
- 34 sites in Germany
- Volunteers
- 12 people
- Sponsor
- University of Witten/Herdecke
Surgical Site Infection
Roles of Prophylactic Subcutaneous Drain in Preventing Surgical Site Infection in Surgical Wound After Abdominal Surgery
Surgical site infections (SSI) pose a common challenge in the field of surgery. Current evidence and literature do not provide clear consensus whether the use of subcutaneous drainage will help reduce the incidence of SSI in…
- Trial name
- NCT06063629
- Testing
- Subcutaneous drain, No drain
- Volunteers
- 180 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Acute Kidney Injury, Cardiac Surgery
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery
Cardiac surgery with cardiopulmonary bypass exposes patients to the risk of post-operative acute kidney injury. In the specific setting of cardiac surgery, acute kidney injury is often of multifactorial origindue to particular…
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Sodium/Glucose Cotransporter Inhibitor 2
- Trial name
- SGLT2i-PO-AKI (NCT06432751)
- Testing
- Post Operative Acute Kidney Injury
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Knee Injuries, Joint Surface Knee Lesions
A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee
The purpose of the study is to support market adoption and global market access via collection of long-term effectiveness, safety, and radiographic data.
- Trial name
- NCT06916728
- Testing
- Marketed Product - MP01, Surgical Standard of Care
- Where
- 8 sites in United States, Belgium and 4 more
- Volunteers
- 170 people
- Sponsor
- Smith & Nephew, Inc.
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