Clinical trials: Post Surgical Wound
Acute Kidney Injury After Adult Cardiac Surgery
The Effect of High Single Dose of Dexamethasone in Prevention of Post-operative Acute Kidney Injury in Cardiac Surgeries Requiring Cardiopulmonary Bypass
The aim of the current study is to assess the effect of intra operative single high dose dexamethasone (1 mg/kg) in decreasing the incidence of post-operative acute kidney injury after cardiac surgeries with cardiopulmonary bypass
- Trial name
- NCT06783634
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Benign Biliary Stricture, Biliary Stricture
Kaffes Stent in the Management of Post-surgical Biliary Strictures
Post-surgical biliary strictures are common especially after cholecystectomy. Standard treatment involves the performance of multiple procedures over a 1 year period at least using several plastic stents to achieve permanent…
- Conditions
- Benign Biliary Stricture, Biliary Stricture, Cholangitis, Bile Duct Stricture
- Trial name
- NCT03716232
- Testing
- Metallic stent, Multiple plastic stents
- Where
- 3 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Ankle Fracture, Postoperative Treatment
Cast or Functional Ankle Orthosis After Ankle Fracture Surgery
The goal of this randomized clinical trial was to compare the effect of 6-week casting versus 2-week casting followed by 4-week ankle bracing in adult patients with surgically treated ankle fractures.
- Trial name
- NCT06559111
- Testing
- 2-week casting followed by 4-week bracing, 6-week casting
- Volunteers
- 134 people
- Sponsor
- Töölö Hospital
Atrial Fibrillation, Myocardium; Injury
Statin Therapy In Cardiac Surgery
The purpose of STICS trial (Statin Therapy In Cardiac Surgery) is to test whether perioperative treatment with Rosuvastatin 20 mg once daily prevents post-operative atrial fibrillation and reduces perioperative irreversible…
- Trial name
- STICS (NCT01573143)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 1,922 people
- Sponsor
- University of Oxford
Acute Kidney Injury, Immune Deficiency
Immunoparalysis in Acute Kidney Injury After Cardiac Surgery
Infection and sepsis are common after acute kidney injury (AKI) and increase mortality. In this study, the investigators will determine whether patients with acute kidney injury after cardiac surgery have immunosuppression as…
- Trial name
- NCT03922958
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Rectal Cancer, Retention, Urinary
Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early, Mid or Late Urinary Catheter Removal in Patients With Rectal Resection
DESIGN: Randomized, open-label and parallel clinical trial, assigned to early, mid, or late withdrawal of urinary catheter with a 1: 1: 1 allocation ratio.
- Conditions
- Rectal Cancer, Retention, Urinary, Urinary Tract Infections, Surgical Site Infection
- Trial name
- RAOREC (NCT04751149)
- Testing
- Removal of Urinary Catheter
- Where
- Spain
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia
Knee Injuries
Effects of Intraarticular IL1-Ra on Pain and Inflammatory Mediators After Knee Arhroscopy
This project investigates the relation between acute pain and local inflammation. Pain reported by the patients for knee arthroscopy are compared with local changes in inflammatory mediators by using microdialysis technique.
- Trial name
- NCT01997138
- Testing
- Anakinra 100 mg in 2 ml saline IA
- Where
- Norway
- Sponsor
- Oslo University Hospital
Hydrocephalus, Ventriculoperitoneal Shunt
Clinical Observation of V-P Shunt and Application of "Three-step Disinfection" to Reduce Post-operative Infection Rate
A randomized, single blind, parallel controlled, multicenter clinical study was performed in which patients who had undergone a cerebrospinal fluid to peritoneal shunt that met the criteria were divided into two groups (test and…
- Trial name
- NCT04785248
- Testing
- Three-step disinfection
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Baiyun Liu
Ankle Fracture
Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)
This study is a randomized controlled trial assessing pain control in ankle fractures repaired with open reduction and internal fixation.
- Trial name
- NCT02480621
- Testing
- Liposomal Bupivacaine with Bupivacaine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Jamaica Hospital Medical Center
Surgical Wound Healing, Botulinum Toxin, Type A
Botulinum Toxin Type A for Wound Healing After Laparoscopic Colectomy
This study aims to evaluate the efficacy and safety of botulinum toxin type A (BTX-A) injection as an adjunct to surgical wound healing in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07795463
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Distal Radius Fracture
Effects of Action Observation Therapy and Motor Imagery Administered During Immobilization Period After Surgical Fixation of Distal Radius
The goal of this trial is to verify the effectiveness of Motor Imagery and Action Observation Training in subjects undergoing surgery for distal radius fracture fixation.
- Trial name
- NCT05867199
- Testing
- Motor Imagery and Action Observation Training
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Clinico Humanitas
Surgery, Critical Illness
Sedation Optimisation Strategy (S.O.S.) Ventilation
Use of sedatives and analgesics is common in mechanically ventilated patients hospitalized in Intensive Care Unit (ICU). That is called " sedation " and aimed to reduce both pain and anxiety and also to allow an effective and…
- Conditions
- Surgery, Critical Illness, Mechanical Ventilation Complication, Organ Dysfunction Syndrome
- Trial name
- NCT01486121
- Testing
- Therapy strategy
- Where
- 3 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Montpellier
Hip Fracture Surgery, Cardiovascular Prevention
Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention
A third of patients undergoing surgery for a hip fracture develop a myocardial injury (i.e., an elevated troponin measurement), and these patients are at substantial risk of death and morbidity.
- Conditions
- Hip Fracture Surgery, Cardiovascular Prevention, Venous Thromboembolism (VTE)
- Trial name
- HIPSTER-Pilot (NCT07228663)
- Testing
- rivaroxaban and ASA, Low-molecular weight heparin, Fondaparinux
- Where
- 3 sites in Canada, Italy
- Volunteers
- 100 people
- Sponsor
- McMaster University
Rotator Cuff Tears
Hydrotherapy Versus Classical Rehabilitation After Surgical Rotator Cuff Repair
Postoperative rehabilitation following rotator cuff repair is important to promote tendon healing, restore strength, and recover normal function.
- Trial name
- NCT05106842
- Testing
- Hydrotherapy, Land-based Therapy
- Where
- Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- La Tour Hospital
Hip Replacement
Surgical Adhesive Drapes for Prevention and Healing of Wound Infections After Total Hip Arthroplasty
The purpose of this study is to support the rational use of iodophor-impregnated surgical adhesive drapes for preventing wound infections after total hip arthroplasty.
- Trial name
- NCT02707302
- Testing
- Iodophor-impregnated adhesive drapes group, Iodophor-free adhesive drapes group
- Volunteers
- 120 people
- Sponsor
- Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Diaphragm Injury, Phrenic Nerve Paralysis
Measurement of Diaphragmatic Dysfunction After Thoracic Surgery
This study aims to measure diaphragmatic dysfunction with ultrasonography and nerve stimulation of the phrenicus nerve, in patients undergoing thoracic surgery for lung and esophageal cancer, and correlate measures of…
- Conditions
- Diaphragm Injury, Phrenic Nerve Paralysis, Thoracic Cancer, Postoperative Complications
- Trial name
- NCT04507594
- Testing
- Lung lobectomy OR esophagus cancer resection
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aarhus University Hospital
Major Puerperal Infection, Postpartum, Wound Complications
Negative Pressure Wound Therapy After Cesarean Delivery
This study is aimed at determining whether or not the use of a wound suction device placed on the cesarean incision instead of a standard sterile dressing will decrease the prevalence of wound complications and wound infections…
- Conditions
- Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation
- Trial name
- NCT01637870
- Testing
- Prevena negative pressure wound system
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Abbey Hardy-Fairbanks
Mastectomy, Breast Reconstruction
CiNPWT Using in Mastectomy Wound Care After DIEP Flaps for Breast Reconstruction
Background: Closed-incision negative pressure wound therapy (ciNPWT) is effective in reducing postoperative complications, yet its use in free flap breast reconstruction mastectomy wound remains controversial due to concerns that…
- Conditions
- Mastectomy, Breast Reconstruction, Closed-Incision Negative Pressure Therapy
- Trial name
- NCT07546968
- Testing
- Closed-Incision Negative Pressure Wound Therapy (CiNPWT)
- Where
- Taiwan
- Volunteers
- 253 people
- Sponsor
- Chiayi Christian Hospital
Peritoneal Surface Malignancy, Postoperative Adhesion
SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery
This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery…
- Conditions
- Peritoneal Surface Malignancy, Postoperative Adhesion, Bowel Obstruction, Wound Complications
- Trial name
- NCT07241091
- Testing
- High-Purity Type-I Collagen Scaffold, Standard Peritonectomy Closure
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Hip Fractures
Patient-Centered Education After Hip Fracture Surgery
This randomized controlled trial aims to evaluate the effect of a structured patient-centered educational program on postoperative outcomes among patients undergoing hip fracture surgery.
- Trial name
- PCE-HFS (NCT07739225)
- Testing
- Structured Patient-Centered Educational Program.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
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