Clinical trials: Post Thoracotomy Pain
Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain
Intraoperative Cryoanalgesia for Extended Pain Management Following Thoracotomy
The ICE Study study will compare standard therapy (thoracic epidural) versus a novel approach (Cryoanalgesia combined with thoracic epidural) in subjects undergoing unilateral thoracotomy.
- Conditions
- Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain, Post-thoracotomy Pain Syndrome
- Trial name
- ICE (NCT03538340)
- Testing
- Thoracic Epidural, Intercostal Cryoanalgesia
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of Maryland, Baltimore
Post Operative Pain, Pain, Acute
Post-thoracotomy Pain Management With Active External Warming and Ice Application
The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption.
- Conditions
- Post Operative Pain, Pain, Acute, Thoracic Injury
- Trial name
- NCT05299788
- Testing
- Active external warming, Ice application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Pain
Pain Therapy After Elective Cardiac Surgery
The purpose of this study is to determine generation of a target controlled infusion model for the patient controlled analgesia with the strong analgesic, hydromorphone, after planned open heart surgery, during which the strong…
- Trial name
- PKPDHM-001 (NCT01490268)
- Testing
- Sufentanil, Hydromorphone
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Magnesium Sulphate, Post Pulmonary Resection
Magnesium Infusion for Pain Relief After Thoracotomy. A Randomized Controlled Trial.
All patients were premedicated with oral midazolam 5-15 mg. one hour before surgery. General anesthesia with double lumen endobronchial tube was given. Patient was induced by propofol and fentanyl.
- Conditions
- Magnesium Sulphate, Post Pulmonary Resection, Pain
- Trial name
- NCT01261702
- Testing
- magnesium sulphate
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Post Thoracotomy Pain
Analgesic Efficiency of Erector Spinae Plane Block Versus Thoracic Paravertebral Block in Patients Undergoing Lateral Thoracotomy Using Opoid Sparing Anesthesia
AimoftheWork To assess the efficiency of Opoid free anaesthesia with paravertebral block compared to opoid free anaesthesia with erector spinae plane block in patients undergoing Thoracotomy.
- Trial name
- ESPvsTPVB (NCT07437027)
- Testing
- Group A :Thoracic paravertebral block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Post-thoracotomy Pain Syndrome
Persistent Pain Induced by Uniportal Video-assisted Thoracic Surgery
The investigators investigate the prevalence of PTPS in patients receiving with uniportal video-assisted thoracic surgery (VATS), and early identify neuropathic pain as well as treated with neural protective strategy to target…
- Trial name
- NCT05379816
- Testing
- 5% DW perineural injection
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Thoracic Neoplasm, Chronic Pain Post-Procedural
Preoperative Paravertebral Block in Cancer Surgery of the Lung
The investigators aim to determine whether ultrasound-guided preemptive paravertebral blockade (PVB) local anaesthetic (pre-PVB LA), administered in addition to the post-operative PVB (post-PVB) local anaesthetic (LA) infusion…
- Conditions
- Thoracic Neoplasm, Chronic Pain Post-Procedural, Acute Post-thoracotomy Pain, Anesthesia, Local
- Trial name
- ParaSOL (NCT04209868)
- Testing
- Levo-Bupivacaine Hydrochloride (HCl) 0.5 % in 20mL Injection, 0.9% Sodium Chloride 20mL Injection
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Amantadine, Pregabalin
Adding Amantadine to Pregabalin on Occurrence of Post-thoracotomy Pain Syndrome
This study aims to evaluate the additive effect of Amantadine to Pregabaline in the development of post-thoracotomy pain syndrome.
- Conditions
- Amantadine, Pregabalin, Post-thoracotomy Pain Syndrome
- Trial name
- NCT06833203
- Testing
- Amantadine+ Pregabalin, Pregabalin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Acute Postoperative Pain, Thoracotomy Surgery
Intertransverse Process Block for Postoperative Analgesia After Thoracotomy and Lobectomy
This prospective, randomized, triple-blind, placebo-controlled clinical trial will investigate the effectiveness of the intertransverse process block (ITPB) for postoperative analgesia in patients undergoing elective thoracotomy…
- Conditions
- Acute Postoperative Pain, Thoracotomy Surgery, Intertransverse Process Block
- Trial name
- NCT07335250
- Testing
- Intertransverse Process Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Konya City Hospital
Post Operative Pain
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
A double-blind randomized control study to compare the efficacy of dexmedetomidine versus ketamine as an adjuvant in combination with bupivacaine ultrasound-guided ESP block in patients scheduled for cardiothoracic surgeries with…
- Trial name
- NCT05552391
- Testing
- Bupivacaine, Ketamine Hydrochloride, Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kasr El Aini Hospital
Post Operative Pain
Ketamine Improves Post-Thoracotomy Analgesia
Thoracotomy for lung tumor or for minimally invasive direct coronary artery bypass (MIDCAB) surgery, may be associated with debilitating pain. Ketamine was shown to enhance opioid antinociception and prevent opioid resistance.
- Trial name
- NCT00625911
- Testing
- morphine, morphine ketamine
- Where
- Israel
- Volunteers
- 44 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Neuropathic Pain, Thoracotomy
Sensory Perception After Thoracotomy
The study will investigate characteristics of chronic pain after thoracotomy
- Conditions
- Neuropathic Pain, Thoracotomy, Chronic Pain
- Trial name
- NCT00910949
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
THoracotomy
Extrapleural Intercostal Catheter vs. Thoracic Epidural for Thoracotomy Pain
We will compare thoracic epidural anesthesia which is presently used for management of pain after thoracotomy to an intra-operatively placed extrapleural intercostal catheter. The study wil be double blinded and prospective.
- Trial name
- NCT00373633
- Testing
- Thoracic Epidural, Extrapleural Intercostal Catheter
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Virginia Commonwealth University
Pain, Postoperative, Iatrogenic Injury
Effect of Partial Rib Resection On the Control of Post-thoracotomy Pain
The aim of this study is to evaluate the effect of partial rib resection in reducing acute post-thoracotomy pain
- Conditions
- Pain, Postoperative, Iatrogenic Injury, Post-thoracotomy Pain Syndrome
- Trial name
- NCT04990700
- Testing
- Partial rib resection
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Dexmedetomidine, Ketamine
Dexmedetomidine and Ketamine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
The aim of this study is to compare the role of dexmedetomidine and ketamine as an adjuvant in external oblique intercostal plane block for post thoracotomy pain.
- Conditions
- Dexmedetomidine, Ketamine, External Oblique Intercostal Plane Block, Post Thoracotomy Pain
- Trial name
- NCT06331182
- Testing
- Ketamine, Dexmedetomidine, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Dexmedetomidine, Adjuvant
Dexmedetomidine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain
This study aims to evaluate the role of dexmedetomidine as an adjuvant in external oblique intercostal plane block for post-thoracotomy pain.
- Conditions
- Dexmedetomidine, Adjuvant, External Oblique Intercostal Plane Block, Thoracotomy
- Trial name
- NCT06684535
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Nerve Block
Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Intercostal Nerve Block for Chronic Post-thoracotomy Pain
The patients were divided into two groups by random number method: GroupRD1 group and GroupRD2 group were given general anesthesia and intercostal nerve block.The drug for intercostal nerve block was 0.33% ropivacaine +2.333mg…
- Trial name
- NCT05556122
- Testing
- intercostal nerve block, lateral intercostal nerve block, ropivacaine + compound betamethasone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Pain, Postoperative
Comparison of the Efficacy of Erector Spina Plane Block and Thoracic Epidural Analgesia After Thoracotomy
In patients who undergoing lobectomy with thoracotomy incision, the effectiveness of erector spina plane block in post-operative analgesia management is at least as much as thoracic epidural anesthesia.
- Trial name
- ESPBTEAPAIN (NCT05402917)
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mesut Aslan
Chronic Postoperative Pain
Does a Multimodal no-Compression Suture Technique of the Intercostal Space Reduce Chronic Post-Thoracotomy Pain?
Chronic post-thoracotomy pain is a significant adverse outcome of thoracic surgery. transcollation technology evaluated with a prospective randomized trial the effect of a multimodal no-compression suture technique of the…
- Trial name
- NCT02630849
- Testing
- intercostal muscle flap and pericostal no-compression suture, Standard suture technique of the intercostal space
- Volunteers
- 380 people
- Sponsor
- University of Roma La Sapienza
Esketamine, Pain
Esketamine and Butorphanol for Post-Lobectomy Pain
Post-thoracotomy pain syndrome (PTPS) affects respiratory function, hindering sputum clearance and ventilation, and represents a significant complication of thoracic surgery.
- Conditions
- Esketamine, Pain, Post-thoracotomy Pain Syndrome, Thoracic Diseases
- Trial name
- NCT06398834
- Testing
- Esketamine, Butorphanol
- Where
- China
- Volunteers
- 223 people
- Sponsor
- Second People's Hospital of Hefei City