Clinical trials: Post Trauma Nightmares
Stress Disorders, Post-Traumatic, Sleep Disorders
Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance
The purposes of this study are: to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees…
- Trial name
- NCT00202449
- Testing
- prazosin, paroxetine
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Nightmares, Insomnia
Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life
Exposure to trauma, especially when it manifests as Posttraumatic Stress Disorder (PTSD), results in numerous negative consequences for patients, families, and society.
- Conditions
- Nightmares, Insomnia, Posttraumatic Stress Disorder
- Trial name
- NCT01009112
- Testing
- PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Diego
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Stress Disorder, Post-Traumatic
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
The purpose of this study is to determine whether prazosin will reduce the incidence of nightmares, sleep disturbance, and overall symptoms in combat trauma-exposed individuals with PTSD.
- Trial name
- NCT00108420
- Testing
- Prazosin
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Post-Traumatic
A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
This randomized, double-blind, placebo-controlled trial of doxazosin will assess doxazosin's effectiveness for PTSD nightmares, subjective sleep quality, and non-nightmare PTSD symptoms in adult men and women veterans with full…
- Trial name
- NCT03339258
- Testing
- Doxazosin Mesylate, Extended Release
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Posttraumatic Stress Disorder
Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests
Post-traumatic stress disorder (PTSD) affects many individuals who experience a traumatic event. There are a variety of treatment options for PTSD, including psychotherapy (talk therapy) options, as well as medications, such as…
- Trial name
- PREDICT (NCT03539614)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Nightmares, REM-Sleep Type, PTSD
Mental Imagery and Targeted Memory Reactivation in PTSD
With this protocol, investigators examine whether targeted memory reactivation (TMR), a technique used to strengthen memories, can accelerate remission of traumatic nightmares and post-traumatic stress disorder (PTSD)…
- Trial name
- NCT05933109
- Testing
- Imagery Rehearsal Therapy and Targeted memory reactivation during REM sleep, Imagery Rehearsal Therapy
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Geneva
Post Traumatic Stress Disorder, Anxiety
The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.
We hypothesize that prevention of Sleep Disordered Breathing among PTSD patients with nasal CPAP will result improve their anxiety, insomnia and alcohol craving (among those who use alcohol to control their symptoms).
- Conditions
- Post Traumatic Stress Disorder, Anxiety, Nightmares, Unrefreshed Sleep
- Trial name
- PTSD (NCT01512771)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northport Veterans Affairs Medical Center
Nightmares, PTSD
Integrating Sleep, Nightmare and PTSD Treatments
The purpose of the proposed pilot study is to extend previous findings regarding the efficacy of a brief treatment for chronic posttrauma nightmares and sleep problems by integrating this treatment with evidence-based treatment…
- Trial name
- CPTERRT (NCT02236390)
- Testing
- Exposure, Relaxation, and Rescripting Therapy, Cognitive Processing Therapy - Cognitive
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Tulsa
Posttraumatic Stress Disorder, Insomnia
An Efficient Treatment for Posttraumatic Injury for Firefighters
The goal of this two-arm pilot randomized controlled trial is to test a behavioral intervention that integrates three evidence-based cognitive behavioral interventions (written exposure therapy; WET, cognitive behavioral therapy…
- Conditions
- Posttraumatic Stress Disorder, Insomnia, Nightmare
- Trial name
- NCT05950035
- Testing
- Written Exposure Therapy (WET), Cognitive Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Palo Alto Veterans Institute for Research
Stress Disorders, Post-Traumatic, Sleep Disorders
Imagery Rescripting for Posttraumatic Nightmares in Rural Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) Veterans With Posttraumatic Stress Disorder (PTSD)
Many service members returning from Iraq and Afghanistan have difficulties adjusting back to civilian life. Research shows that symptoms of posttraumatic stress disorder (PTSD) are particularly high in returning Operation…
- Trial name
- NCT00837382
- Testing
- MEDVAMC Nightmare Treatment, Telepsychiatry Nightmare Treatment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- US Department of Veterans Affairs
Insomnia, PTSD - Post Traumatic Stress Disorder
Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD
This study is a two-arm individually randomized group treatment clinical trial evaluating behavioral therapies for insomnia, nightmares, and PTSD.
- Conditions
- Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
- Trial name
- NCT07069517
- Testing
- Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Palo Alto Veterans Institute for Research
Insomnia, Nightmares
Initial Study of Insomnia/Nightmare Group Treatment for Posttraumatic Stress Disorder (PTSD)
Many combat Veterans suffer from posttraumatic stress disorder (PTSD), an anxiety disorder that develops after an extremely stressful event or events. PTSD is associated with problems falling asleep or staying asleep.
- Conditions
- Insomnia, Nightmares, Posttraumatic Stress Disorder
- Trial name
- NCT01314612
- Testing
- Cognitive-Behavioral Insomnia and Nightmare Group
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Trauma, Insomnia
Treatment of Comorbid Sleep Disorders and Post Traumatic Stress Disorder (PTSD)
The primary objective of the current study is to determine if providing cognitive-behavioral therapy of Insomnia and nightmares (CBTin) and Cognitive Processing Therapy of PTSD (CPT) results in greater PTSD and sleep symptom…
- Conditions
- Trauma, Insomnia, Nightmares
- Trial name
- NCT02773693
- Testing
- Cognitive Processing Therapy-Cognitive Only (CPT), Cognitive Behavioral Therapy of Insomnia and Nightmares (CBTin), Continuation Cognitive Processing Therapy-Cognitive Only (CPT)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of North Texas, Denton, TX
PTSD, Military Activity
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members.
- Conditions
- PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder
- Trial name
- NCT05414708
- Testing
- Art Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Walter Reed National Military Medical Center
Posttraumatic Stress Disorder, Cardiovascular Diseases
NightWare and Cardiovascular Health in Adults With PTSD
The purpose of this study is to determine whether NightWare therapeutic intervention improves biomarkers of vascular aging and autonomic function in adults with nightmares related to PTSD.
- Conditions
- Posttraumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT05365607
- Testing
- NightWare
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Stress Disorders, Post-Traumatic, Sleep Disorders
Randomized Clinical Trial of Imagery Rescripting Treatment In Veterans With Trauma-Related Nightmares And Posttraumatic Stress Disorder (PTSD)
Research shows that symptoms of posttraumatic stress disorder (PTSD) are particularly high in veterans, and that trauma-related nightmares and sleep disturbances are common in veterans with PTSD.
- Trial name
- NCT00837109
- Testing
- Veteran Nightmare Treatment, Treatment-as-usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- US Department of Veterans Affairs
PostTraumatic Stress Disorder, Sleep Disorder
NightWare Open Enrollment Study
This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress…
- Conditions
- PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders
- Trial name
- NWOES (NCT03828656)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- NightWare
Posttraumatic Stress Disorder
MGH Trauma-related Nightmares SDI Study
Interested individuals will first complete a telephone screening followed by a series of structured clinical interviews to diagnose PTSD and comorbid psychiatric disorders, confirm initial inclusion criteria, rule out exclusion…
- Trial name
- NM (NCT05195684)
- Testing
- imaginal probe
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
A Transdiagnostic Sleep Health Intervention for Veterans With PTSD
Sleep disturbance is a major problem in Veterans with posttraumatic stress disorder (PTSD). This study will test a version of a sleep treatment that's been shown to be effective in the general population, with some changes to…
- Trial name
- NCT06549049
- Testing
- TranS-C for PTSD, Sleep Psychoeducation Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- VA Office of Research and Development