Clinical trials: Post Traumatic Stress
Chronic Pain, PTSD
Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Gulf War Veterans (a DoD/VA defined service era corresponding to the first Gulf War under operations Desert Storm and Desert Shield 1990-1991), especially those who present with Post-Traumatic Stress Disorder (PTSD), are…
- Trial name
- NCT04236284
- Testing
- Home-based tDCS, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Post-Traumatic Stress Disorder (PTSD)
The PRISM Pilot Trial for Post-Traumatic Stress Disorder
A Prospective, Single-Arm, Open-Label Pilot Trial, to Assess Safety and Effectiveness of Process-Instructed Self neuro-Modulation ("Prism"), as an Adjunct to Standard of Care, in Subjects with Post-Traumatic Stress Disorder (PTSD)
- Trial name
- NCT04891614
- Testing
- PRISM
- Where
- 5 sites in United States, Israel
- Volunteers
- 87 people
- Sponsor
- GrayMatters Health Ltd.
Posttraumatic Stress Disorders, PTSD
Effect of D-cycloserine on Treatment of Posttraumatic Stress Disorder (PTSD) in Youth
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 7-12 year old…
- Trial name
- NCT01157416
- Testing
- D-cycloserine, CBT
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Tulane University School of Medicine
Major Depressive Disorder (MDD), Anxiety Disorders
Retrospective Observational Study of Intensity Effects in Psychedelic-assisted Treatment
This retrospective observational study examines the effects of psychedelic-assisted psychotherapy (PAP) with lysergic acid diethylamide (LSD) or psilocybin in patients with treatment-resistant depressive, anxiety, or addictive…
- Conditions
- Major Depressive Disorder (MDD), Anxiety Disorders, Substance Use Disorder (SUD), PTSD - Post Traumatic Stress Disorder
- Trial name
- NCT07164287
- Testing
- Lysergic Acid Diethylamide (LSD) or psilocybin
- Where
- Switzerland
- Volunteers
- 376 people
- Sponsor
- University Hospital, Geneva
Burnout, Professional, Self Compassion
Better Together Physician Coaching to Mitigate Burnout Amongst Clinicians
Better Together Physician Coaching ("Better Together", or "BT"), a 4-month, web-based positive psychology multimodal coaching program was built to decrease burnout in medical trainees.
- Conditions
- Burnout, Professional, Self Compassion, Flourishing, Imposter Syndrome
- Trial name
- NCT05635448
- Testing
- Better Together Physician Coaching Program, No intervention - waitlist control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sleep, Intrusive Memories
Sleep and Wellbeing Study
Most people will experience a psychologically traumatic event, such as a life-threatening accident, at some point in their life.
- Conditions
- Sleep, Intrusive Memories, Posttraumatic Stress Disorder
- Trial name
- NCT03012685
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Oxford
Posttraumatic Stress Disorder (PTSD)
Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD)
Posttraumatic stress disorder (PTSD) is a major public health problem in this country. It is estimated that at least one out of every seven women in our society have been the victim of childhood sexual abuse at least once before…
- Trial name
- NCT00672776
- Testing
- paroxetine
- Volunteers
- 40 people
- Sponsor
- Emory University
Stress Disorders, Post-Traumatic
A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women
The purpose of the proposed DVA cooperative study is to evaluate the efficacy of exposure therapy for treating PTSD and associated problems in female veterans and active duty military personnel.
- Trial name
- NCT00032617
- Testing
- Prolonged Exposure, Present Centered Therapy
- Where
- 13 sites in United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
TBI, Suicide Prevention
A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans
Risk of Veteran suicide is elevated during the first year of transition from military service to civilian life. Most Veteran suicides occur among Veterans who are not connected to VA healthcare.
- Conditions
- TBI, Suicide Prevention, Veterans, PTSD
- Trial name
- SH-SP (NCT05995678)
- Testing
- STEP-Home-SP, Transition Assistance Program, VA Solid Start
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Well-Being, Psychological, Mood Disturbance
Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms
The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a…
- Conditions
- Well-Being, Psychological, Mood Disturbance, Emotional Regulation, Dissociation
- Trial name
- NCT07217925
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Post Traumatic Stress Disorder, Traumatic Brain Injury
TMS-fNIRS Personalized Dosing
The intent of this study is to establish technical feasibility in a clinical population (PTSD, with or without mild TBI) of personalized TMS-fNIRS technology.
- Trial name
- NCT05916417
- Testing
- TMS-fNIRS over the dl-PFC
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Florida State University
PTSD, Depression
Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children
The goal of this study is to assess Parenting STAIR Modular (PSTAIR-M), a promising and innovative intervention for military-connected mothers (MCM) who have experienced trauma and their young children (ages 2-10).
- Conditions
- PTSD, Depression, Parent-Child Relations
- Trial name
- NCT06262178
- Testing
- Parenting-STAIR Modular (PSTAIR-M)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- New York University
Posttraumatic Stress Disorder, Moral Injury
Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury
Given the prevalence of posttraumatic stress disorder (PTSD) and moral injury in combat Veterans and the limitations to current treatments, novel approaches are needed to target both PTSD and moral injury and directly impact…
- Trial name
- NCT03906240
- Testing
- Moral Elevation intervention
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Stress, Psychological, Post-traumatic Stress
Wellbeing and Stress Among Mobile Phone Dispatched Lay Responders
The aim of this study is to provide detailed information on state of mind, psychological wellbeing and stress for lay responders dispatched to suspected OHCA via a mobile phone application.
- Trial name
- NCT04165668
- Testing
- Exposure: First on scene
- Where
- 2 sites in Sweden
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Post Traumatic Stress Disorder
Biochemical and Physiological Response to Stressogenic Stimuli
Post-traumatic stress disorder (PTSD) is characterized by physiological changes, some of which are thought to be chronic, while others are observed in response to stressogenic stimuli.
- Trial name
- NCT04076215
- Testing
- Stressogenic stimulus, Biobeat smart watch and adhesive biosensor patches.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nadav Goldental
Well Being, Happiness
Laughie Prescription on the Well-being, Happiness, and Posttraumatic Stress Level of Nursing Students Affected by the Earthquake
This study aimed to evaluate the effect of the Laughie Prescription on Well-being, Happiness, and Postraumatic stress levels of nursing students affected by the earthquake in Türkiye.
- Conditions
- Well Being, Happiness, Post Traumatic Stress Disorders
- Trial name
- NCT07157176
- Testing
- Daily 3-Minute Laughter Practice (Laughie Prescription)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Traumatic Brain Injury, Post-Concussive Symptoms
Long-Term Outcomes Following HBOT
This study is designed to better understand the long-term effects of hyperbaric oxygen therapy (HBOT). Our goal is to determine whether improvements after treatment are maintained over time and whether additional benefits appear…
- Conditions
- Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
- Trial name
- NCT07732374
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Summit Hyperbarics and Wellness
Stress Disorder, Post Traumatic
D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD
This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans.
- Trial name
- NCT00356278
- Testing
- D-Cycloserine, Alprazolam, Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Emory University
Psychosocial Problem, Psychological Distress
Evaluating Impacts of CSS for Veterans and Their Families in Ukraine
This cluster-randomized controlled trial (c-RCT) evaluates the effectiveness of a brief, single-session psychosocial workshop, "CETA Short Session" (CSS), for reducing symptoms of distress and functional impairment and increasing…
- Conditions
- Psychosocial Problem, Psychological Distress, Engagement, Patient
- Trial name
- NCT04234815
- Testing
- CETA Short Session (CSS), Psychoeducation and Safety
- Where
- Ukraine
- Volunteers
- 1,193 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
PTSD
Prevention of Combat-related PTSD Using Attention Bias Modification (ABM): A Randomized Controlled Trial
Military deployment to combat zones involves exposure to trauma at a higher than average rate and therefore presents a unique opportunity to study predisposing factors to posttraumatic stress reactions and test strategies…
- Trial name
- NCT01723215
- Testing
- Active ABMT8, Active ABMT4
- Where
- Israel
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
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