Clinical trials: Post Traumatic Stress
PTSD
Cannabidiol and Prolonged Exposure
The trial will include a randomized control trial to evaluate the efficacy of using Cannabidiol (CBD), a non-intoxicating cannabinoid, as an adjunctive to Prolonged Exposure therapy (PE).
- Trial name
- CBD-PE (NCT03518801)
- Testing
- Prolonged Exposure, Cannabidiol
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Lymphoma, Posttraumatic Stress Disorder
Longitudinal Survey Analysis in Lymphoma Survivors
Posttraumatic Stress Disorder (PTSD) is a well-documented phenomenon that occurs in cancer survivors. PTSD is known to cause problems with anxiety, depression, and quality of life.
- Conditions
- Lymphoma, Posttraumatic Stress Disorder, Posttraumatic Growth, Coping
- Trial name
- CLEAR Stress (NCT01469754)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Child Abuse, Sexual, Post-Traumatic Stress Disorder
Body-Oriented Therapy for Sexual Abuse Recovery
The purpose of this study is to examine and compare the effects of two body therapy approaches in women who have experienced child sexual abuse.
- Conditions
- Child Abuse, Sexual, Post-Traumatic Stress Disorder, Dissociation
- Trial name
- NCT00097305
- Testing
- Body-Oriented Therapy, Standardized Massage Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Posttraumatic Stress Disorder
Client-directed Cognitive Processing Therapy
This study will take place over approximately 6 months and includes 3 assessment appointments (where information will be gathered, but no direct treatment provided) and 12 treatment sessions of cognitive processing therapy if…
- Trial name
- CPT (NCT02684994)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Indianapolis
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder
Assessing and Enhancing Social Support
Posttraumatic stress disorder (PTSD) is a common and impairing problem among Veterans, many of whom first seek treatment in primary care settings. PTSD is linked to reduced quality of life and increased rates of suicide.
- Trial name
- NCT05187156
- Testing
- Behavioral Activation and Social Engagement, Treatment as usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post Traumatic, Substance-Related Disorders
Cognitive Therapy for PTSD in Addiction Treatment
The purpose of this phase of the study is to assess the feasibility of a cognitive behavioral therapy for post-traumatic stress disorder (PTSD) in persons receiving outpatient services at an addiction treatment program.
- Trial name
- NCT00685451
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- 3 sites in United States
- Volunteers
- 49 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
PTSD, Stroke
Methylphenidate for Ptsd and Stroke Veterans
Veterans with post-traumatic stress disorder (PTSD) have an increased risk of developing ischemic stroke. Veterans enduring PTSD face difficulties in managing their PTSD severity after suffering from a stroke.
- Trial name
- NCT04885257
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Posttraumatic Stress Disorder
Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests
Post-traumatic stress disorder (PTSD) affects many individuals who experience a traumatic event. There are a variety of treatment options for PTSD, including psychotherapy (talk therapy) options, as well as medications, such as…
- Trial name
- PREDICT (NCT03539614)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder (MDD, Anxiety Disorder, Generalized
Serotonin Variants & Gut Microbiota in Mental Health
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway (including serotonergic system, methylation cycle, intestinal barrier integrity, and inflammatory response…
- Conditions
- Major Depressive Disorder (MDD, Anxiety Disorder, Generalized, Stress Disorders, Post-Traumatic, Panic Disorder
- Trial name
- NCT07634458
- Testing
- SNP Genotyping and Gut Metagenomics
- Volunteers
- 30 people
- Sponsor
- Neurobiologix
PTSD, Post-Traumatic Stress Disorder
Characterization of the Use of Antipsychotics in PTSD During the Past Seven Years
The primary objective is to examine the percentage of patients with PTSD who were prescribed an antipsychotic over the past seven years in the VA Network 7 (AL, GA, SC) and compare the percentage on an annual basis.
- Trial name
- NCT00230893
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Stress Disorders, Post-Traumatic
Trial to Evaluate Efficacy of Magnetic Resonant Therapy (MRT) in PTSD
The purpose of this study is to establish the efficacy of Magnetic Resonant Therapy in treating Post Traumatic Stress Disorder in Veterans.
- Trial name
- NCT02268084
- Testing
- Magnetic EEG/ECG-guided Resonance Therapy
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Wave Neuroscience
Post Traumatic Stress Disorder
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD
This study is evaluating the safety and efficacy of TSND-201 in adults with PTSD. Eligible participants will enter a 4-week Treatment Period where they will be randomized 1:1:1 to receive one of two doses of TSND-201 or placebo…
- Trial name
- EMPOWER-2 (NCT07836647)
- Testing
- TSND-201
- Where
- 6 sites in United States
- Volunteers
- 300 people
- Sponsor
- Transcend Therapeutics
Insomnia, Depression - Major Depressive Disorder
Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI)
The goal of this pilot clinical trial is to evaluate the effectiveness and delivery method of a CBTI self-managed digital mobile application in service members. The main questions it aims to answer are: RQ1.
- Conditions
- Insomnia, Depression - Major Depressive Disorder, PTSD
- Trial name
- NCT07335276
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 144 people
- Sponsor
- Madigan Army Medical Center
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
Posttraumatic Stress Disorder
Telemental Health and Cognitive Processing Therapy for Rural Combat Veterans With Posttraumatic Stress Disorder
The immediate objective of this project was to evaluate the clinical effectiveness of a telemental health modality (video-teleconferencing) for providing an evidence-based group intervention (Cognitive Processing Therapy; CPT) to…
- Trial name
- CPTVTEL (NCT00879255)
- Testing
- Cognitive Processing Therapy Group Videoteleconference, Cognitive Processing Therapy Group In-Person
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Post-Traumatic, Marijuana Abuse
Applying Mixed Methods to Identify Links Between PTSD Symptoms, Cannabis Use, and Functional Behaviors With Personalized Feedback Intervention Development
Many Veterans live with posttraumatic stress disorder (PTSD) and use cannabis to manage distress, despite limited supportive evidence.
- Trial name
- NCT07721285
- Testing
- Personalized Feedback Session (PFS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Neuroprotective/Neurotrophic Effect of Lexapro® in Patients With Posttraumatic Stress Disorder
The objectives of the current study are 1. to evaluate the efficacy of escitalopram in treatment for post-traumatic stress disorder, 2.
- Trial name
- NCT01008098
- Testing
- escitalopram (lexapro)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Seoul National University Hospital
IBS - Irritable Bowel Syndrome, Constipation
Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders
The purpose of this study is study bowel symptoms, quality of life, and personal factors that may affect your health. In Aim 1 of this study participants will be invited to complete 6 survey-based questionnaires online.
- Trial name
- PTSD (NCT04060121)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Indiana University
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