Clinical trials: Post Traumatic Stress
PTSD
Effect of tDCS Timing on Safety Memory in PTSD
The primary purpose of this study is to investigate the effects of tDCS timing on extinction memory in PTSD. A total of 90 participants will be randomized equally across one of three groups: 1.
- Trial name
- NCT04152772
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Butler Hospital
Type 1 Diabetes
Prevalence of Post Traumatic Stress Disorder Related to Diabetes Diagnosis or Severe Hypoglycaemia in Adult With Type 1 Diabetes
In France, the adult population living with diabetes in 2016 is estimated at more than 3.3 million patients treated. Type 1 diabetes (T1DM) represents 5.6% of diabetic patients (approximately 185,000 patients).
- Trial name
- NCT05662657
- Testing
- Diagnostic Test: PCL-S Questionnaire
- Where
- 2 sites in France
- Volunteers
- 297 people
- Sponsor
- Hospital St. Joseph, Marseille, France
PTSD
PTSD Treatment for Incarcerated Men and Women: AV
This research will help identify if a PTSD treatment group, called Cognitive Processing Therapy (CPT), that is used in community settings is helpful in reducing PTSD symptoms among people who are incarcerated.
- Trial name
- NCT07283757
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Wisconsin, Madison
Heart Defects, Congenital, Anxiety in Pregnancy
HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis
Babies with single ventricle congenital heart disease (SVCHD) are often diagnosed during pregnancy. While prenatal diagnosis has important clinical benefits, it is often stressful and overwhelming for parents, and many express a…
- Conditions
- Heart Defects, Congenital, Anxiety in Pregnancy, Depression, Postpartum, Trauma, Psychological
- Trial name
- HeartGPS (NCT06175104)
- Testing
- HeartGPS
- Where
- 4 sites in United States, Australia
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Schizophrenia, Bipolar Disorder
Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness
Many individuals with serious mental illness have difficulty accurately interpreting interpersonal cues and effectively engaging in social exchanges.
- Conditions
- Schizophrenia, Bipolar Disorder, Depressive Disorder, Major, Stress Disorder, Post-Traumatic
- Trial name
- NCT05491538
- Testing
- Social Cognition and Interaction Training-Work Edition (SCIT-WE)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
PTSD
Delivery of Self Training and Education for Stressful Situations-Telephone Version
This study will evaluate a telephone-delivered cognitive-behavioral psychotherapy intervention designed for primary care treatment of combat-exposed service members with PTSD.
- Trial name
- DESTRESS-T (NCT01502449)
- Testing
- DESTRESS-T, Optimized Usual Care (OUC)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Uniformed Services University of the Health Sciences
Post Traumatic Stress Disorder, Depression
The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy
Background: The treatment of traumatised refugees is one of the areas within the field of psychiatry with the weakest evidence for the different types of treatment.
- Trial name
- PTF3 (NCT01569685)
- Testing
- Venlafaxine, Sertraline
- Where
- Denmark
- Volunteers
- 207 people
- Sponsor
- Charlotte Sonne
Concussion, Stress Disorders, Post-Traumatic
Concussion and Post Traumatic Stress in Traumatic Brain Injury
Mild brain injury or concussion affects about four million Americans each year. Some people recover completely while others, especially those with multiple concussions, develop chronic headaches, neurodegenerative diseases and…
- Trial name
- CAPIT (NCT02119533)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
PTSD
Intensive Weekend Retreat Multi-Couple Group Therapy for PTSD
The purpose of this study is to test an intensive, multi-couple group version of a couple therapy for PTSD delivered to active duty Service Members or Veterans with PTSD and their romantic partners in a single weekend retreat.
- Trial name
- NCT03158558
- Testing
- Accelerated, Multi-Couple Group CBCT for PTSD
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Penn State University
Post Traumatic Stress Disorder
Simple Cognitive Task After Trauma EKUT RCT
This research study is designed to investigate the effects of a simple cognitive task (a memory cue following by playing the computer game "Tetris") on intrusive memories ("flashbacks") and other symptoms after a traumatic event.
- Trial name
- NCT04185155
- Testing
- Simple cognitive task
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Karolinska Institutet
Post-Traumatic Stress Disorder
The Role of Computerized Training in Post-Traumatic Stress Disorder
The purpose of this study is to determine whether a computerized training, "Cognitive Bias Modification" targetting appraisals (CBM-App), can reduce dysfunctional appraisals of trauma in patients with Post-Traumatic Stress…
- Trial name
- NCT02687555
- Testing
- Cognitive Bias Modification of Appraisals (CBM-App), Peripheral Vision Task (control condition)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Ruhr University of Bochum
Cigarette Smoking, Nicotine Dependence
Treatment of Smoking Among Individuals With PTSD
This study will examine the effect of combining prolonged exposure, a cognitive-behavioral treatment program for post-traumatic stress disorder (PTSD) with medication (varenicline) and counseling treatments for smoking cessation.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
- Trial name
- NCT00937235
- Testing
- Varenicline, Medication Management Counseling, Prolonged Exposure
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Pennsylvania
Stress Disorders, Post Traumatic
Exposure Therapy for Active Duty Soldiers With Post Traumatic Stress Disorder
This study is evaluating the efficacy of virtual realty exposure therapy (VRET)by comparing it to prolonged exposure therapy (PE) and a waitlist (WL) group for the treatment of post traumatic stress disorder (PTSD) in active duty…
- Trial name
- VRPE (NCT01193725)
- Testing
- Prolonged Exposure Therapy (PE), Virtual Reality Exposure Therapy (VRET), Waitlist
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- National Center for Telehealth and Technology
PTSD
Sex/Gender Differences in Risk and Resilience to PTSD; Implication of Oxytocin
The purpose of the study is to use fMRI to investigate amygdala response to fearful faces in men and women with and without PTSD who have experienced childhood trauma.
- Trial name
- NCT01963078
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Megan Moran-Santa Maria
Post-traumatic Stress Disorder, Hypertension
TMS for PTSD and Blood Pressure
In this randomized clinical trial, we will test the short and longer term effects of repetitive transcranial magnetic stimulation (TMS) on blood pressure among reproductive aged female participants with elevated symptoms of…
- Trial name
- NCT05512143
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lifespan
Fear, GAD
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments.
- Conditions
- Fear, GAD, Emotional Memory, PTSD
- Trial name
- NCT05120635
- Testing
- Deep Brain Stimulation, Virtual and augmented reality tasks
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Anxiety Depression, Post Traumatic Stress Disorder
Neuropsychological Sequelae and Long COVID-19 Fatigue
An association of fatigue with post-viral neuropsychological disturbs has been reported. Among patients hospitalized with COVID-19 there is an increased incidence of anxiety and depression symptoms.
- Conditions
- Anxiety Depression, Post Traumatic Stress Disorder, Mental Fatigue, COVID-19
- Trial name
- PostCoV2Psy (NCT05323318)
- Testing
- Neuropsychological Sequelae
- Where
- 6 sites in Portugal
- Volunteers
- 200 people
- Sponsor
- Centro Hospitalar Universitario do Algarve
Stress Disorders, Post-Traumatic
A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
This randomized, double-blind, placebo-controlled trial of doxazosin will assess doxazosin's effectiveness for PTSD nightmares, subjective sleep quality, and non-nightmare PTSD symptoms in adult men and women veterans with full…
- Trial name
- NCT03339258
- Testing
- Doxazosin Mesylate, Extended Release
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
PTSD
Monoamine Transporters Genotypes: Risk of PTSD and Related Comorbidities
Dr. Wang's merit review is aimed at providing a better understanding of the relationship between SLC6A3/SLC6A4 and the mental health of veterans exposed to high levels of combat stress, specifically focusing on PTSD symptoms…
- Trial name
- MTG (NCT00403455)
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Mindfulness and Present Centered Therapies for PTSD: Efficacy and Mechanisms
This project will study whether a new therapy that includes the practice of forms of meditation is helpful for combat veterans returning from deployments in Iraq or Afghanistan suffering with posttraumatic stress disorder (PTSD).
- Trial name
- NCT01347749
- Testing
- Mindfulness & Compassion Meditation-based Exposure Therapy, Present Centered Therapy for PTSD
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Michigan
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