Clinical trials: Post Traumatic Stress
Psychoeducation on Trauma Reactions, Psychoeducation on Safety Behaviors and How to Fade Them
Online Psychoeducation for the Prevention of PTSD
Research on decreasing safety behaviors in therapy has been restricted to treatments for other anxiety disorders and has not included PTSD.
- Conditions
- Psychoeducation on Trauma Reactions, Psychoeducation on Safety Behaviors and How to Fade Them, Monitoring-only Control
- Trial name
- NCT03496714
- Testing
- Psychoeducation on trauma reactions, Psychoeducation on safety behaviors
- Sponsor
- University of Texas at Austin
Mental Health, Cognition
Bio-Experiential Spaces for Mental Health in Healthworkers
Recharge Rooms are immersive, biophilic private spaces designed to ameliorate trauma, anxiety, and stress. They feature multisensory input that is inspired by nature, as has previously been found to confer physiological benefits.
- Conditions
- Mental Health, Cognition, Anxiety
- Trial name
- NCT05227352
- Testing
- Biophilic design experience
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
PTSD - Post Traumatic Stress Disorder
Reported Experience Measurement on Reducing Patient Discomfort in Intensive Care
Hospitalisation in intensive care is always traumatic and can lead to a long rehabilitation process, slowed down by symptoms of anxiety and/or depression, and/or post-traumatic stress disorder (PTSD).
- Trial name
- PREMREA (NCT07525284)
- Testing
- PREMREA program
- Where
- France
- Volunteers
- 1,242 people
- Sponsor
- Almaviva Sante
Posttraumatic Stress Disorder (PTSD)
Cognition and Psychotherapy in PTSD
Posttraumatic stress disorder (PTSD) is prevalent among combat Veterans and is a substantial public health burden. Several psychotherapies, including cognitive processing therapy (CPT) and prolonged exposure therapy, have been…
- Trial name
- NCT03641924
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
A Randomized Controlled Trial of Metacognitive Therapy and EMDR for Posttraumatic Stress Disorder
Posttraumatic stress disorder (PTSD) is a frequently occurring and often debilitating anxiety disorder resulting from exposure to trauma.
- Trial name
- NCT01955590
- Testing
- Metacognitive therapy, EMDR, Treatment as usual
- Where
- Norway
- Volunteers
- 96 people
- Sponsor
- Norwegian University of Science and Technology
Trauma-related Mental Health Symptoms
Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans
The current proposal aims to refine and examine an intervention called Calm Moms. Calm Moms is a web-based treatment program designed to reduce anxiety, stress, and low mood symptoms among pregnant Veterans with a history of…
- Trial name
- NCT06906185
- Testing
- Calm Moms-V, Care As Usual
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Efficacy Mechanism of N-acetylcysteine in Patients With Posttraumatic Stress Disorder
It has been suggested that N-acetylcysteine exerts neuroprotective effects by regulating neurotransmitters and cell signaling pathways.
- Trial name
- NCT01664260
- Testing
- N-acetylcysteine
- Where
- South Korea
- Sponsor
- Ewha Womans University
Posttraumatic Stress Disorders
PTSD Symptom Reduction by Propranolol Given After Trauma Memory Activation
This study is a randomized, double-blind, placebo-controlled clinical trial of propranolol combined with trauma memory reactivation, to determination if this approach is effective in treating PTSD symptoms.
- Trial name
- NCT00645450
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Post-traumatic Stress Disorder
Telerehabilitation for OIF/OEF Returnees With Combat-Related Traumatic Brain Injury
The scientific objective of this program is to meet the rehabilitation needs of combat wounded Veterans with mild to moderate Traumatic Brain Injury (TBI) via telerehabilitation and determine the effect of this modality of care…
- Trial name
- NCT00676182
- Testing
- Telerehabilitation
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Depression, Anxiety, PTSD
Psychedelics and Wellness Study (PAWS)
The Psychedelics and Wellness Study (PAWS), is an anonymous online survey investigating the interrelationship between psychedelics and wellness.
- Trial name
- PAWS (NCT04040582)
- Where
- United States
- Volunteers
- 3,234 people, healthy volunteers welcome
- Sponsor
- WILD 5 Wellness
Post-Traumatic Stress Disorders
Immune and Endocrine Function in Post-Traumatic Stress Disorder
This is a study investigating immune function and relationships to the hypothalamic-pituitary-adrenal (HPA) axis in Post-traumatic stress disorder (PTSD) compared to controls without PTSD.
- Trial name
- NCT00100490
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
PTSD, Depression
Violence Prevention for Adolescent Girls With Prior Maltreatment
The purpose of the study is to adapt and test an evidence-based trauma treatment program for adolescent girls with histories of child maltreatment.
- Conditions
- PTSD, Depression, Aggression, Victimization
- Trial name
- GAIN (NCT02765048)
- Testing
- GAIN Program
- Where
- 3 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depressive Episode, Posttraumatic Stress Disorder
Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation
The purpose of this study is to determine whether transcranial magnetic stimulation (TMS) is effective in the treatment of suicidal thinking in individuals with a depressive episode and either posttraumatic stress disorder…
- Conditions
- Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
- Trial name
- NCT01212848
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Posttraumatic Stress Disorder (PTSD)
Trajectories of Psychopathology in Response to NET
Narrative Exposure Therapy (NET) has been proven to be effective in the treatment of Posttraumatic Stress Disorder (PTSD) and trauma-related depression in more than a dozen controlled clinical trials.
- Trial name
- TOP-NET (NCT02852616)
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Posttraumatic Stress Disorder
Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD
The purpose of this clinical trial is to learn if MDMA-assisted therapy is safe and effective in people with PTSD. The main question it aims to answer is: Do two open-label sessions of MDMA-assisted therapy reduce PTSD symptoms?…
- Trial name
- NUMCAP1 (NCT04968938)
- Testing
- midomafetamine, Therapy
- Sponsor
- Resilient Pharmaceuticals
PTSD, Cognitive Impairment
(Neuro)Cognitive Remediation for Adults With OSIs
(Neuro)Cognitive remediation (CR) is an intervention for people experiencing cognitive impairments that interfere with their daily functioning.
- Conditions
- PTSD, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT06813378
- Testing
- (Neuro)Cognitive Remediation
- Volunteers
- 20 people
- Sponsor
- Nova Scotia Health Authority
Post-Traumatic Stress Disorder
Therapeutic Effects of the Processing of Positive Memories Technique on Posttrauma Health
The current study will examine daily-level impacts of a technique addressing positive memory retrieval on thoughts, feelings, and health among individuals with trauma experiences.
- Trial name
- PPMT (NCT06680193)
- Testing
- Processing of Positive Memories Technique
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Texas, Denton, TX
Trauma, Psychological, Learning Disability
Narrative Exposure Therapy for Adults With an Intellectual Disability
The goal of this naturalistic single case series design is to investigate if an adapted Narrative Exposure Therapy protocol can be effective, is feasible, and acceptable for adults with a mile learning disability.
- Conditions
- Trauma, Psychological, Learning Disability, PTSD, Intellectual Disability, Mild
- Trial name
- NCT06934109
- Testing
- Narrative Exposure Therapy (NET)
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Nottingham
Nightmares, REM-Sleep Type, PTSD
Mental Imagery and Targeted Memory Reactivation in PTSD
With this protocol, investigators examine whether targeted memory reactivation (TMR), a technique used to strengthen memories, can accelerate remission of traumatic nightmares and post-traumatic stress disorder (PTSD)…
- Trial name
- NCT05933109
- Testing
- Imagery Rehearsal Therapy and Targeted memory reactivation during REM sleep, Imagery Rehearsal Therapy
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Geneva
Stress Disorders, Posttraumatic, Depression
Re-Engineering Systems for the Primary Care Treatment for PTSD
The study is an evaluation of a systemic intervention to enhance the delivery of care according to practice guidelines for posttraumatic stress disorder (PTSD).
- Trial name
- RESPECT-PTSD (NCT00373698)
- Testing
- Three Component Model of Collaborative Care
- Where
- 4 sites in United States
- Volunteers
- 195 people
- Sponsor
- US Department of Veterans Affairs