Clinical trials: Post Traumatic Stress
Posttraumatic Stress Disorder (PTSD)
Mindfulness-based Stress Reduction for PTSD in Road Traffic Accident Victims: A Randomized Controlled Trial
The goals of the study are to investigate the effects of mindfulness-based stress reduction (MBSR) on PTSD among road traffic accident victims.
- Trial name
- NCT07521020
- Testing
- mindfulness-based stress reduction
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Universiti Sains Malaysia
Generalized Anxiety Disorder, Social Anxiety Disorder
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression
This early-stage trial aims to examine the feasibility, tolerability, and safety of Floatation-REST (Reduced Environmental Stimulation Therapy) or an active comparison condition in 75 participants with clinical anxiety and…
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03899090
- Testing
- Float pool, Float chair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Anxiety, Post-Traumatic Stress Disorder
Exercise, Mood and Stress Study
Multiple studies indicate that exercise is effective in treating depressed mood and reducing anxiety sensitivity. As depressive symptoms and anxiety sensitivity are elevated in individuals with anxiety and depressive disorders…
- Conditions
- Anxiety, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT02887027
- Testing
- Exercise4Mood Intervention
- Volunteers
- 4 people
- Sponsor
- Boston University Charles River Campus
Obstructive Sleep Apnea
A Randomized Cross Over Trial of Two Treatments for Sleep Apnea in Veterans With Post-Traumatic Stress Disorder
Sleep disturbances are cardinal features of Veterans with post traumatic stress disorder (PTSD). In particular, obstructive sleep apnea is reported to occur more frequently in patients with PTSD compared to those without PTSD and…
- Trial name
- NCT01569022
- Testing
- CPAP, MAD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder
Trauma Treatment in Norwegian Child Advocacy Centers
Norwegian child and advocacy centers´ core activities include both forensic services (e.g., forensic interviews) and follow-up services (e.g., treatment), aiming to coordinate the different services involved in each case to…
- Trial name
- NCT05314829
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Depression, Anxiety
Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Disorder, Stress
- Trial name
- Blueprint 2 (NCT06538246)
- Testing
- Blueprint, Education program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Duke University
Influenza, Pneumonia, Viral
Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study
Influenza A (H1N1) v2009 infection was responsible throughout the world of viral pneumonia and severe pulmonary edema requiring rescue therapeutics such as extracorporeal oxygenation.
- Conditions
- Influenza, Pneumonia, Viral, Pulmonary Fibrosis, Quality of Life
- Trial name
- RESPIFLU (NCT01271842)
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
PTSD and Trauma-related Symptoms
LIFU Mechanisms for PTSD in Healthcare Workers
The goal of this clinical trial is to evaluate whether low-intensity focused ultrasound (LIFU) of the ventral anterior cingulate cortex (vACC) can normalize dysfunctional brain activation patterns and behaviors in frontline…
- Trial name
- NCT07164105
- Testing
- Low intensity focused ultrasound
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Posttraumatic Stress Disorder
Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing
PTSD occurs in as many as 17% of US military Veterans and is associated with a host of negative, long-term consequences to the individual, their families, and society at large.
- Trial name
- NCT04241094
- Testing
- Loved one assisted treatment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
PTSD (Childbirth-Related), Psychological Wellbeing
Feasibility and Efficacy of GTEP for Birth Trauma
This clinical study aims to evaluate the feasibility and initial efficacy of Group Traumatic Episode Protocol (GTEP) for reducing trauma symptoms (measured by the PCL-5 and City BiTS) for individuals following a traumatic…
- Conditions
- PTSD (Childbirth-Related), Psychological Wellbeing, Bonding
- Trial name
- NCT07246356
- Testing
- Group Traumatic Episode Protocol (GTEP)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Birmingham
Pregnancy Early, PTSD
PTSD Screening in Pregnant Black Women
This study will compare the effectiveness of two active screening interventions in improving post-traumatic stress disorder (PTSD) symptoms, maternal perinatal care utilization, satisfaction utilization of mental healthcare…
- Trial name
- NCT06522022
- Testing
- Culturally Responsive SBIRT for OB, Brief Screening for PTSD
- Where
- 2 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Emory University
Gunshot Entry Wound
Predictors of Treatment Failure Among Patients With Gunshot Wounds and Post-traumatic Stress Disorder
The 82.1% treatment failure of post-traumatic stress disorder(PTSD), associated with gunshot wounds, is related to high incidence of chronic pain syndrome as well as resistance to the PTSD treatment.
- Trial name
- NCT04689022
- Testing
- Mississippi Scale for Combat-Related PTSD (M-PTSD), visual analogue scale (VAS), Douleur Neuropathique 4 questions (DN4)
- Volunteers
- 218 people
- Sponsor
- Vasyl' Horoshko
Post Traumatic Stress Disorder, Intensive Care Psychiatric Disorder
Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial
Primary objective is to evaluate the feasibility of delivering an online early Eye Movement Desensitisation Reprocessing (EMDR) Recent Traumatic Events Protocol (R-TEP) to patients who have survived Covid-19 related critical…
- Conditions
- Post Traumatic Stress Disorder, Intensive Care Psychiatric Disorder, Anxiety Disorders, Depression
- Trial name
- Cov-EMERALD (NCT04455360)
- Testing
- Eye Movement Desensitisation and Reprocessing Recent traumatic Event Protocol
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Posttraumatic Stress Disorder
Evaluating Safety and Efficacy of Cannabis in Participants With Chronic Posttraumatic Stress Disorder
The purpose of this study is to evaluate the safety and efficacy of vaporized cannabis in participants with chronic, treatment-resistant posttraumatic stress disorder.
- Trial name
- NCT02517424
- Testing
- High THC/Low CBD Cannabis, High THC/High CBD Cannabis, Low THC/Low CBD Cannabis
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Tilray
Post Traumatic Stress Disorder
Efficacy of Internet-delivered Cognitive-behavior Therapy for PTSD
The goal of this clinical trial is to compare therapist-guided internet delivered prolonged exposure to an active control condition( therapist-guided internet delivered cognitive behavioral therapy containing relaxation…
- Trial name
- NCT05934162
- Testing
- Therapist-supported internet-delivered prolonged exposure, Therapist-supported internet-delivered CBT
- Where
- Sweden
- Volunteers
- 286 people
- Sponsor
- Karolinska Institutet
Posttraumatic Stress Disorder
Effects of Delta9-tetrahydrocannabinol (THC) on Retention of Memory for Fear Extinction Learning in PTSD: R33 Study
The goal of this study is to look at how a type of drug called cannabinoids are related to the processing of fear signals, the experience of emotions and fear, and the pattern of activity in the brain that is involved in these…
- Trial name
- NCT04080427
- Testing
- Dronabinol 7.5 milligram oral capsule
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Wayne State University
Stress Disorders, Post-Traumatic
Meditation Interventions for Treatment of PTSD in Veterans
Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder which results in serious impairments in interpersonal, occupational and social functioning.
- Trial name
- VMP (NCT01548742)
- Testing
- Mindfulness-Based Stress Reduction (MBSR), Present-Centered Group Therapy (PCGT)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder, PTSD
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
A Phase 2, Open-Label Study to explore the efficacy, safety, and tolerability of psilocybin-assisted therapy in women with sexual assault-related Posttraumatic Stress Disorder (PTSD).
- Trial name
- SUN004 (NCT06902974)
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Sunstone Medical
Childbirth Problems, Post Traumatic Stress Disorder
Eye Movement Desensitization and Reprocessing vs Supportive Expressive Dynamic Psychotherapy for Childbirth Trauma
There is increasing evidence that about 30% of women evaluate their childbirth as traumatic and that women could develop post-traumatic stress disorder (PTSD) in response to events of birth.
- Trial name
- NCT03972410
- Testing
- EMDR, SEDP
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
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